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个人简介

招生专业 071008-发育生物学 071009-细胞生物学 071007-遗传学 招生方向 植物发育生物学 植物细胞生物学 植物分子遗传学 教育背景 1990-01--1994-04 荷兰Wageningen University 博士 1980-09--1989-12 兰州大学 学士、硕士、在职博士 工作经历 1987,7--1990,1 兰州大学生物系 助教 工作简历 2003-03~现在, 遗传发育所, 研究员、副所长、所长、国重主任 2000-08~2003-02,新加坡淡马锡生命科学实验室, 实验室主任, PI 1996-08~2000-08,新加坡分子农业研究所, Research fellow 1996-01~1996-07,纽约冷泉港实验室, 博士后 1994-05~1995-12,Wageningen University, 博士后 1987-08~1990-12,兰州大学, 助教/硕士 教授课程 发育生物学 奖励信息 (1) 中国科学院优秀教师奖, 部委级, 2018 (2) 中国科学院优秀教师奖, 部委级, 2016 (3) 2016年度生命科学领域十大进展, , 其他, 2016 (4) 全国优秀科技工作者, 国家级, 2016 (5) 科学中国人(2015)年度人物, , 其他, 2015 (6) 被子植物有性生殖的分子机理研究, 二等奖, 国家级, 2013 (7) 中国科学院“宝洁优秀研究生导师, , 部委级, 2008 (8) 国际植物有性生殖研究会杰出服务奖, 其他, 2008 (9) 新世纪百千万人才工程国家级人才人选, , 部委级, 2007 (10) 优秀研究生指导教师奖, , 部委级, 2007 专利成果 ( 1 ) 利用玉米Lc基因培育抗棉铃虫植物的方法, 发明, 2012, 第 1 作者, 专利号: 2010 1 0173444.7 ( 2 ) 一种逆境诱导表达Ghi10424启动子及其应用, 发明, 2018, 第 1 作者, 专利号: 201510059715.9 发表著作 (1) Chapter 2,Handbook of Seed Science and Technology, The Haworth Press Inc, 2006-09, 第 1 作者 (2) Chapters 7 & 8, Plant Embryogenesis, in Methods in Molecular Biology 427., Humana Press, 2008-09, 第 3 作者 (3) Chapter 13 Pollen Germination and Tube Growth. in Plant Developmental Biology-Biotechnological Perspectives, Springer, 2010-09, 第 2 作者 (4) 郑国锠细胞生物学, Zheng Guochang Cell Biology, 科学出版社, 2015-03, 第 1 作者 (5) Chapters 14 & 15, Plant Germline Development: Methods and Protocols, in Methods in Molecular Biology, Springer, 2017-10, 第 3 作者 科研项目 ( 1 ) 植物生殖发育生物学创新群体, 主持, 国家级, 2010-01--2016-12 ( 2 ) 被子植物胚囊信号调控与花粉管响应的分子机制, 主持, 国家级, 2014-01--2018-12 ( 3 ) 雌雄配子体识别的分子遗传机理, 主持, 国家级, 2013-01--2017-12 ( 4 ) 共生识别与固氮蛋白质机器, 参与, 国家级, 2017-06--2020-07 ( 5 ) 重要性状功能基因克隆及验证, 主持, 国家级, 2008-12--2016-06 ( 6 ) 双受精的分子机制, 主持, 国家级, 2020-01--2024-12 参与会议 (1)Fertilization and zygote development in Arabidopsis 2018全国发育生物学大会 2018-10-14 (2)被子植物花粉管导向机制研究 2018年中国植物学会全国代表大会 2018-10-10 (3)Pollen tube guaidance: The interplay betweent the male and female gametophyte. 2018年国际农业生物技大会(ABIC) 2018-09-15 (4)AGL80 acts as a trancritpional repressor in the central cell 2018-06-11 (5)植物合子发育的分子机制 2018全国细胞生物学大会 2018-04-10 (6)Pollen tube guaidance: The interplay betweent the male and female gametophyte. 全国植物生物学大会 2017-10-12 (7)Pollen tube guaidance: The interplay betweent the male and female gametophyte. 全国细胞生物学会 2017-09-26 (8)Pollen tube guidance in flowering plants--The interplay between the male and female gametophytes 2017-05-22 (9)The role of peroxisome biogenesis in pollen tube growth Yang Weicai 2014-07-13 (10)POD1, a novel ER protein, controls the pollen tube response to female cues in Arabidopsis Yang Weicai 2012-02-13 (11)Female gametophyte development in Arabidopsis: The role of RNA biogenesis. Yang Weicai 2010-08-02

研究领域

植物有性生殖包括生殖器官形成、孢子发生、配子体发育、雌雄配子体间的相互识别、受精和胚胎发育等过程,其结果是种子和果实形成。氮素是植物生长和产量形成的基础,生物固氮是维持大气氮平衡的重要因素,豆科植物共生固氮对农业生产和土壤改良非常重要,人们梦寐以求的目标是让水稻、小麦等非豆科植物也能固氮,但前提是充分认识共生固氮的机制。这些研究不仅对于人类认识自然具有深远的科学意义,而且对农业生产也具有重要的现实意义。本实验室重点开展以下四个方面的研究: 1)胚囊发育的遗传调控; 2)花粉管与胚囊间相互识别的分子基础; 3)受精及受精卵发育的分子机制; 4) 大豆共生固氮的分子细胞生物学机制。

近期论文

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1. Jun Tang, J., Jia, P., Xin, P., Chu, J., Shi, D.*, and Yang, W.* (2020). AtTRM61/AtTRM6 complex is a bona fide tRNA N1-methyladenosine methyltransferase in Arabidopsis. Journal of Experimental Botany eraa100. doi: 10.1093/jxb/eraa100. 2. Zhang, M.X., Zhu, S.S., Xu, Y.C., Guo, Y.L., Yang, W.C.*, and Li, H.J.* (2020). Transcriptional repression specifies the central cell for double fertilization. PNAS doi/10.1073/pnas.1909465117. 3. Meng, J. G., Liang, L., Jia, P.F., Wang, Y.C., Li, H.J.*, and Yang, W.C.* (2020). Integration of ovular signals and exocytosis of a Ca2+ channel by MLOs in pollen tube guidance. Nature Plants 6: 143–153. 4. Zhao, P., Wang, F., Li, N., Shi, D.Q., and Yang, W.C. (2020). Pentatricopeptide repeat protein MID1 modulates nad2 intron 1 splicing and Arabidopsis development. Scientific Reports DOI: 10.1038/s41598-020-58495-5. 5. Wu, H.M., Xie, D.J., Tang, Z.S., Shi, D.Q., and Yang, W.C. (2020). PINOID regulates floral organ development by modulating auxin transport and interacts with MADS16 in rice. Plant Biotechnology Journal DOI: 10.1111/pbi.13340. 6. Shi, C., Luo, P., Du, Y.T., Chen, H., Huang, X., Cheng, T.H., Luo, A., Li, H.J., Yang, W.C., Zhao, P., and Sun, M.X. (2019). Maternal control of suspensor programmed cell death via gibberellin signaling. Nature Communications 10: 3484. 7. Long, Y., Xie, D., Zhao, Y., Shi, D.*, and Yang, W.C.* (2019). BICELLULAR POLLEN 1 is a modulator of DNA replication and pollen development in Arabidopsis. New Phytologist 222: 588–603 8. Meng, J.G., Zhang, M.X., Yang, W.C.*, and Li, H.J.* (2019). TICKET attracts pollen tubes and mediates reproductive isolation between relative species in Brassicaceae. SCIENCE CHINA Life Sciences 62:1413-1419 9. Li, Y., Li., H.J., Morgan, C., Bomblies, K., Yang, W., and Qi, B. (2019). Both male and female gametogenesis require a fully functional protein S-acyl transferase 21 in Arabidopsis thaliana. Plant Journal 100:754-767. 10. Jia, P.F., Xue, Y., Li, H.J., and Yang, W.C. (2019). LOT regulates TGN biogenesis and Golgi structure in plants. Plant Signaling & Behavior 14(3): e1573100. 11. Jia, P.F., Xue, Y., Li, H.J., and Yang, W.C. (2018). Golgi-localized LOT regulates trans-Golgi network biogenesis and pollen tube growth. PNAS 115: 12307-12312 12. Li, H.J.* and Yang, W.C.* (2018). Ligands switch model for pollen-tube integrity and burst. Trend Plant Sci 23: 369-372. 13. van Velzena, R., Holmer, R., Bua, F., Rutten, L., van Zeijl, A., Liu, W., Santuari, L., Cao, Q., Sharma, T., Shen, D., Roswanjaya, Y., Wardhani, T.A.K., Kalhor, M.S., Jansen, J., van den Hoogen, J., Güngör, B., Hartog, M., Hontelez, J., Verver, J., Yang, W.C., Schijlen, E., Repin, R., Schilthuizen, M., Schranz, M.E., Heidstra, R., Miyata, K., Fedorova, E., Kohlen, W., Bisseling, T., Smit, S., and Geurts, R. (2018). Comparative genomics of the nonlegume Parasponia reveals insights into evolution of nitrogen-fixing rhizobium symbioses. PNAS 115: E4700-E4709. 14. Li, H.J.*, Meng, J.G., and Yang, W.C.* (2018). Multilayered signaling pathways for pollen tube growth and guidance. Plant Reproduction 31, 31-41. 15. Sun, M.X., Yang, W.C., and Higashiyama, T. (2018). Special issue on plant reproduction research in Asia. Plant Reproduction 31:1-2. 16. Higashiyama, T.*, and Yang, W.C.* (2017). Gametophytic pollen tube guidance: Attractant peptides, gametic controls, and receptors. Plant Physiology 173(1):112-121. 17. Jia, P.F., Li, H.J., and Yang, W.C. (2017). Analysis of peroxisome biogenesis in pollen by confocal microscopy and transmission electron microscopy. In Plant Germline Development: Methods and Protocols (Ed. Anja Schmidt), PP. 173-180. Methods in Plant Molecular Biology 1669. Springer protocols. 18. Jia, P.F., Li, H.J., and Yang, W.C. (2017). 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2018-11-30-2023-07-31,中国遗传学会, 秘书长、副理事长 2013-07-31-2019-07-31,Plant Reproduction, 编委 2011-07-31-2020-07-31,Scientific Reports, 编委 2010-07-31-2019-07-31,Journal of Genetics and Genomics, 副主编 2009-12-01-2014-11-30,北京市细胞生物学会 , 副理事长 2008-12-31-2014-11-29,国家自然科学基金委杰出青年基金评审委员会, 委员 2008-08-01-2014-08-30,《植物学报》, 副主编 2008-07-31-2016-07-29,Journal of Integrative Plant Biology, 副主编 2008-07-30-2018-11-26,中国遗传学会理事, 理事 2007-09-01-2011-08-31,中国细胞生物学会理事 , 理事 2007-08-01-2020-06-29,Molecular Plant, 编委 2006-08-01-2010-07-31,Cell Research, 编委 2006-01-01-2010-12-30,国家自然科学基金委生命科学部专家评审组, 成员 2005-12-31-2016-05-31,Multinational Arabidopsis Steering Committee, 中国区代表

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