Zhang, Heping - Yale University - Biological & Biomedical Sciences

个人简介

Dr. Zhang published over 250 research articles and monographs in theory and applications of statistical methods and in several areas of biomedical research including epidemiology, genetics, child and women health, mental health, substance use, and reproductive medicine. He directed a training program in mental health research that was funded by the NIMH. He directs the Collaborative Center for Statistics in Science that coordinates the Reproductive Medicine Network to evaluate treatment effectiveness for infertility. He is a fellow of the American Statistical Association and a fellow of the Institute of Mathematical Statistics. He was named the 2008 Myrto Lefokopoulou distinguished lecturer by Harvard School of Public Health and a Medallion Lecturer by the Institute of Mathematical Statistics. In 2011, he received the Royan International Award on Reproductive Health. PhD Stanford University (1991)

研究领域

Child Psychiatry; Epidemiology; Infertility; Mental Health; Pregnancy; Psychiatry; Computational Biology; Statistics; Genomics; Biostatistics

近期论文

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Generalized Score Test of Homogeneity for Mixed Effects Models Zhang, H.P. and Zhu, H.T. Generalized Score Test of Homogeneity for Mixed Effects Models. Annals of Statistics 34: 1545-1569, 2006. Detection of Genes for Ordinal Traits in Nuclear Families and a Unified Approach for Association Studies Zhang, H.P., Wang, X., and Ye, Y. Detection of Genes for Ordinal Traits in Nuclear Families and a Unified Approach for Association Studies. Genetics 172: 693-699, 2006. Analysis of Ordinal Traits for Pedigree Data Zhang, H.P., Feng, R., and Leckman, J. Linkage Analysis of Ordinal Traits for Pedigree Data. Proceedings of the National Academy of Sciences, USA 101: 16739-16744, 2004. Genome Wide Scan of Hoarding in Sibling Pairs both Diagnosed with Gilles de la Tourette Syndrome Zhang, H.P. Leckman, J.F., Pauls, D.L., Tsai, C.-P., Kidd, K.K., Campos, M.R. and The Tourette Syndrome Association International Consortium for Genetics. Genome Wide Scan of Hoarding in Sibling Pairs both Diagnosed with Gilles de la Tourette Syndrome. American Journal of Human Genetics 70: 2002. Tree-based linkage and association analyses of asthma Zhang, H.P., Tsai, C.-P., Yu, C.-Y., and Bonney, G. Tree-based linkage and association analyses of asthma. Genetic Epidemiology 21: S317-S322, 2001. Recursive Partitioning for Tumor Classification with Gene Expression Microarray Data Zhang, H.P., Yu, C-Y, Singer, B. and Xiong, M. Recursive Partitioning for Tumor Classification with Gene Expression Microarray Data. Proceedings of the National Academy of Sciences USA 98: 6730-6735, 2001. Classification Trees for Multiple Binary Responses Zhang, H.P. Classification Trees for Multiple Binary Responses. Journal of the American Statistical Association 93: 180-193, 1998. Bi X, Yang L, Li T, Wang B, Zhu H, Zhang H: Genome-wide mediation analysis of psychiatric and cognitive traits through imaging phenotypes. Hum Brain Mapp. 2017 May 22; 2017 May 22. PMID: 28544218 Engmann L, Jin S, Sun F, Legro RS, Polotsky AJ, Hansen KR, Coutifaris C, Diamond MP, Eisenberg E, Zhang H, Santoro N, Reproductive Medicine Network.: Racial and ethnic differences in the polycystic ovary syndrome metabolic phenotype. Am J Obstet Gynecol. 2017 May; 2017 Jan 16. PMID: 28104402 Diamond MP, Legro RS, Coutifaris C, Alvero R, Robinson RD, Casson PA, Christman GM, Huang H, Hansen KR, Baker V, Usadi R, Seungdamrong A, Bates GW, Rosen RM, Schlaff W, Haisenleder D, Krawetz SA, Barnhart K, Trussell JC, Santoro N, Eisenberg E, Zhang H, Eunice Kennedy Shriver National Institute of Child Health and Human Development Reproductive Medicine Network.: Sexual function in infertile women with polycystic ovary syndrome and unexplained infertility. Am J Obstet Gynecol. 2017 Apr 26; 2017 Apr 26. PMID: 28455078 Xiao F, Niu Y, Hao N, Xu Y, Jin Z, Zhang H: modSaRa: a computationally efficient R package for CNV identification. Bioinformatics. 2017 Apr 26; 2017 Apr 26. PMID: 28453611 Styer AK, Jin S, Liu D, Wang B, Polotsky AJ, Christianson MS, Vitek W, Engmann L, Hansen K, Wild R, Legro RS, Coutifaris C, Alvero R, Robinson RD, Casson P, Christman GM, Christy A, Diamond MP, Eisenberg E, Zhang H, Santoro N, National Institute of Child Health and Human Development Reproductive Medicine Network.: Association of uterine fibroids and pregnancy outcomes after ovarian stimulation-intrauterine insemination for unexplained infertility. Fertil Steril. 2017 Mar; 2017 Jan 12. PMID: 28089575 Wei D, Shi Y, Li J, Wang Z, Zhang L, Sun Y, Zhou H, Xu Y, Wu C, Liu L, Wu Q, Zhuang L, Du Y, Li W, Zhang H, Legro RS, Chen ZJ: Effect of pretreatment with oral contraceptives and progestins on IVF outcomes in women with polycystic ovary syndrome. Hum Reprod. 2017 Feb; 2016 Dec 19. PMID: 27999118 Mehta CM, Gruen JR, Zhang H: A method for integrating neuroimaging into genetic models of learning performance. Genet Epidemiol. 2017 Jan; 2016 Nov 18. PMID: 27859682 Song C, Min X, Zhang H: THE SCREENING AND RANKING ALGORITHM FOR CHANGE-POINTS DETECTION IN MULTIPLE SAMPLES. Ann Appl Stat. 2016 Dec; 2017 Jan 5. PMID: 28090239 Xiao F, Cai G, Zhang H: Segregation Analysis Suggests That a Genetic Reason May Contribute to "the Dress" Colour Perception. PLoS One. 2016; 2016 Oct 21. PMID: 27768729 Santoro N, Eisenberg E, Trussell JC, Craig LB, Gracia C, Huang H, Alvero R, Casson P, Christman G, Coutifaris C, Diamond M, Jin S, Legro RS, Robinson RD, Schlaff WD, Zhang H, Reproductive Medicine Network Investigators.: Fertility-related quality of life from two RCT cohorts with infertility: unexplained infertility and polycystic ovary syndrome. Hum Reprod. 2016 Oct; 2016 Jul 7. PMID: 27402910 Han G, Schell MJ, Zhang H, Zelterman D, Pusztai L, Adelson K, Hatzis C: Testing violations of the exponential assumption in cancer clinical trials with survival endpoints. Biometrics. 2016 Sep 26; 2016 Sep 26. PMID: 27669414 Mumford SL, Legro RS, Diamond MP, Coutifaris C, Steiner AZ, Schlaff WD, Alvero R, Christman GM, Casson PR, Huang H, Santoro N, Eisenberg E, Zhang H, Cedars MI: Baseline AMH Level Associated With Ovulation Following Ovulation Induction in Women With Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2016 Sep; 2016 May 26. PMID: 27228369