个人简介
PhD State University of New York (1998)
研究领域
Cell Biology; Endocytosis; Exocytosis; Ophthalmology; Physiology; Presynaptic Terminals; Retinal Bipolar Cells
近期论文
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Synaptic ribbons influence the size and frequency of miniature-like evoked postsynaptic currents
Mehta, B., Snellman, J., Chen, S., Li, W. and Zenisek, D. (2013) Synaptic ribbons influence the size and frequency of miniature-like evoked postsynaptic currents. Neuron, 77:516-527 PMCID: PMC3569740
Acute destruction of the synaptic ribbon reveals a role for the ribbon in vesicle priming.
Snellman, J., Mehta, B., Babai, N., Bartoletti, T.M., Francis, A., Akmentin, W., Matthews, G., Thoreson, W. and Zenisek, D. (2011) Nat Neurosci. 2011 Jul 24;14(9):1135-41. doi: 10.1038/nn.2870.
Imaging exocytosis in retinal bipolar cells using TIRF microscopy
Joselevitch C. and Zenisek D. Imaging exocytosis in retinal bipolar cells using TIRF microscopy. Journal of Visualized Experiments 9(28).
Development of new peptide-based tools for studying synaptic ribbon function
Francis, A., Mehta, B. and Zenisek, D. Development of new peptide-based tools for studying synaptic ribbon function. Journal of Neurophysiology, 2011, 166(2): 1028-1037.
Real-time visualization of complexin during single exocytic events
An SJ, Grabner CP and Zenisek D. Real-time visualization of complexin during single exocytic events. Nature Neuroscience 13(5): 577-583. 2010.
Coupling between clathrin-coated pit invagination, cortactin recruitment and membrane scission observed in live cells
Merrifield CJ, Perrais D, Zenisek D. Coupling between clathrin-coated pit invagination, cortactin recruitment and membrane scission observed in live cells. Cell, 121:593-606, 2005.
Recent progress toward understanding the synaptic ribbon
Prescott ED and Zenisek D. Recent progress toward understanding the synaptic ribbon. Curr Opin Neurobiol, 15:431-6, 2005.
Lv C, Stewart WJ, Akanyeti O, Frederick C, Zhu J, Santos-Sacchi J, Sheets L, Liao JC, Zenisek D: Synaptic Ribbons Require Ribeye for Electron Density, Proper Synaptic Localization, and Recruitment of Calcium Channels. Cell Rep. 2016 Jun 21; 2016 Jun 9. PMID: 27292637
Arif Pavel M, Lv C, Ng C, Yang L, Kashyap P, Lam C, Valentino V, Fung HY, Campbell T, Møller SG, Zenisek D, Holtzman NG, Yu Y: Function and regulation of TRPP2 ion channel revealed by a gain-of-function mutant. Proc Natl Acad Sci U S A. 2016 Apr 26; 2016 Apr 11. PMID: 27071085
Graffe M, Zenisek D, Taraska JW: A marginal band of microtubules transports and organizes mitochondria in retinal bipolar synaptic terminals. J Gen Physiol. 2015 Jul. PMID: 26123197
Lv C, Zenisek D: Big minis from hair cells: mechanism and function. Neuron. 2014 Sep 17. PMID: 25233300
Mehta B, Ke JB, Zhang L, Baden AD, Markowitz AL, Nayak S, Briggman KL, Zenisek D, Singer JH: Global Ca2+ signaling drives ribbon-independent synaptic transmission at rod bipolar cell synapses. J Neurosci. 2014 Apr 30. PMID: 24790194
Grabner CP, Zenisek D: Amperometric resolution of a prespike stammer and evoked phases of fast release from retinal bipolar cells. J Neurosci. 2013 May 8. PMID: 23658155
Mehta B, Snellman J, Chen S, Li W, Zenisek D: Synaptic ribbons influence the size and frequency of miniature-like evoked postsynaptic currents. Neuron. 2013 Feb 6. PMID: 23395377
Lv C, Gould TJ, Bewersdorf J, Zenisek D: High-resolution optical imaging of zebrafish larval ribbon synapse protein RIBEYE, RIM2, and CaV 1.4 by stimulation emission depletion microscopy. Microsc Microanal. 2012 Aug; 2012 Jul 26. PMID: 22832038
Francis AA, Mehta B, Zenisek D: Development of new peptide-based tools for studying synaptic ribbon function. J Neurophysiol. 2011 Aug; 2011 Jun 8. PMID: 21653726
Snellman J, Mehta B, Babai N, Bartoletti TM, Akmentin W, Francis A, Matthews G, Thoreson W, Zenisek D: Acute destruction of the synaptic ribbon reveals a role for the ribbon in vesicle priming. Nat Neurosci. 2011 Jul 24; 2011 Jul 24. PMID: 21785435
Xu HP, Furman M, Mineur YS, Chen H, King SL, Zenisek D, Zhou ZJ, Butts DA, Tian N, Picciotto MR, Crair MC: An instructive role for patterned spontaneous retinal activity in mouse visual map development. Neuron. 2011 Jun 23. PMID: 21689598