个人简介
PhD Cornell University (2006)
BS Peking University (2001)
研究领域
Biochemistry; Biophysics; Cell Nucleus; Chromatin; Molecular Biology; Transcription Factors; Gene Expression
近期论文
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Subnuclear Segregation of Genes and Core Promoter Factors in Myogenesis
Yao, J., Fetter, R. D., Hu, P., Betzig, E., and Tjian, R. (2011). Subnuclear Segregation of Genes and Core Promoter Factors in Myogenesis, Genes & Development, 25: 569-580
Spatial compartmentalization at the nuclear periphery characterized by genome-wide mapping
Wu F, Yao J. Spatial compartmentalization at the nuclear periphery characterized by genome-wide mapping. BMC Genomics. 2013 Aug 30;14:591.
Imaging Transcriptional Regulation of Eukaryotic mRNA Genes: Advances and Outlook
Yao J. Imaging Transcriptional Regulation of Eukaryotic mRNA Genes: Advances and Outlook. J Mol Biol. 2017 Jan 6;429(1):14-31.
Identifying Novel Transcriptional and Epigenetic Features of Nuclear Lamina-associated Genes
Wu F, Yao J. Identifying Novel Transcriptional and Epigenetic Features of Nuclear Lamina-associated Genes. Sci Rep. 2017 Dec;7(1):100.
Single-cell, single-mRNA analysis of Ccnb1 promoter regulation
Vishnoi N, Yao J. Single-cell, single-mRNA analysis of Ccnb1 promoter regulation. Sci Rep. 2017 May 18;7(1):2065.
Wu F, Yao J: Identifying Novel Transcriptional and Epigenetic Features of Nuclear Lamina-associated Genes. Sci Rep. 2017 Dec; 2017 Mar 7. PMID: 28273906
Vishnoi N, Yao J: Single-cell, single-mRNA analysis of Ccnb1 promoter regulation. Sci Rep. 2017 May 18; 2017 May 18. PMID: 28522800
Yao J: Imaging Transcriptional Regulation of Eukaryotic mRNA Genes: Advances and Outlook. J Mol Biol. 2017 Jan 6; 2016 Nov 16. PMID: 27865781
Wu F, Olson BG, Yao J: DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments. J Vis Exp. 2016 Jan 27; 2016 Jan 27. PMID: 26862720
Wu F, Yao J: Spatial compartmentalization at the nuclear periphery characterized by genome-wide mapping. BMC Genomics. 2013 Aug 30; 2013 Aug 30. PMID: 23987233
Zhang T, Berrocal JG, Yao J, DuMond ME, Krishnakumar R, Ruhl DD, Ryu KW, Gamble MJ, Kraus WL: Regulation of poly(ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase. J Biol Chem. 2012 Apr 6; 2012 Feb 13. PMID: 22334709
Sim S, Yao J, Weinberg DE, Niessen S, Yates JR 3rd, Wolin SL: The zipcode-binding protein ZBP1 influences the subcellular location of the Ro 60-kDa autoantigen and the noncoding Y3 RNA. RNA. 2012 Jan; 2011 Nov 23. PMID: 22114317
Yao J, Tjian R: Sub-nuclear compartmentalization of core promoter factors and target genes. Cell Cycle. 2011 Aug 1; 2011 Aug 1. PMID: 21670597
Yao J, Fetter RD, Hu P, Betzig E, Tjian R: Subnuclear segregation of genes and core promoter factors in myogenesis. Genes Dev. 2011 Mar 15; 2011 Feb 28. PMID: 21357673
Ardehali MB, Yao J, Adelman K, Fuda NJ, Petesch SJ, Webb WW, Lis JT: Spt6 enhances the elongation rate of RNA polymerase II in vivo. EMBO J. 2009 Apr 22; 2009 Mar 12. PMID: 19279664
Darzacq X, Yao J, Larson DR, Causse SZ, Bosanac L, de Turris V, Ruda VM, Lionnet T, Zenklusen D, Guglielmi B, Tjian R, Singer RH: Imaging transcription in living cells. Annu Rev Biophys. 2009. PMID: 19416065
Yao J, Zobeck KL, Lis JT, Webb WW: Imaging transcription dynamics at endogenous genes in living Drosophila tissues. Methods. 2008 Jul; 2008 Jun 27. PMID: 18586105
Ni Z, Saunders A, Fuda NJ, Yao J, Suarez JR, Webb WW, Lis JT: P-TEFb is critical for the maturation of RNA polymerase II into productive elongation in vivo. Mol Cell Biol. 2008 Feb; 2007 Dec 10. PMID: 18070927
Yao J, Ardehali MB, Fecko CJ, Webb WW, Lis JT: Intranuclear distribution and local dynamics of RNA polymerase II during transcription activation. Mol Cell. 2007 Dec 28. PMID: 18158896
Yao J, Munson KM, Webb WW, Lis JT: Dynamics of heat shock factor association with native gene loci in living cells. Nature. 2006 Aug 31; 2006 Aug 23. PMID: 16929308
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