Toomre, Derek K. - Yale University - Biological & Biomedical Sciences

个人简介

PhD University of California, San Diego (1996) MS University of California, San Diego (1992)

研究领域

Biology; Biophysics; Biotechnology; Chemistry; Nanotechnology; Optics and Photonics

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

phosphoinositide switch controls the maturation and signaling properties of APPL endosomes. Zoncu R, Perera RM, Balkin DM, Pirruccello M, Toomre D, De Camilli P. A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes. Cell. 2009 Mar 20;136(6):1110-21. PubMed PMID: 19303853; PubMed Central PMCID: PMC2705806. Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages. Perera RM, Zoncu R, Lucast L, De Camilli P, Toomre D. Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19332-7. Epub 2006 Dec 8. Spatio-temporal analysis of constitutive exocytosis in epithelial cells. Sebastian R, Diaz ME, Ayala G, Letinic K, Moncho-Bogani J, Toomre D. Spatio-temporal analysis of constitutive exocytosis in epithelial cells. IEEE/ACM Trans Comput Biol Bioinform. 2006 Jan-Mar;3(1):17-32. Both daughter cells traffic and exocytose membrane at the cleavage furrow during mammalian cytokinesis. Goss JW, Toomre DK. Both daughter cells traffic and exocytose membrane at the cleavage furrow during mammalian cytokinesis. J Cell Biol. 2008 Jun 30;181(7):1047-54. Epub 2008 Jun 23. PubMed PMID: 18573914; PubMed Central PMCID: PMC2442215. Fusion of constitutive membrane traffic with the cell surface observed by evanescent wave microscopy. Toomre D, Steyer JA, Keller P, Almers W, Simons K. Fusion of constitutive membrane traffic with the cell surface observed by evanescent wave microscopy. J Cell Biol. 2000 Apr 3;149(1):33-40. PubMed PMID: 10747085; PubMed Central PMCID: PMC2175107. Lipid rafts and signal transduction. Simons K, Toomre D. Lipid rafts and signal transduction. Nat Rev Mol Cell Biol. 2000 Oct;1(1):31-9. Review. Erratum in: Nat Rev Mol Cell Biol 2001 Mar;2(3):216. PubMed PMID: 11413487. Xu Y, Toomre DK, Bogan JS, Hao M: Excess cholesterol inhibits glucose-stimulated fusion pore dynamics in insulin exocytosis. J Cell Mol Med. 2017 May 25; 2017 May 25. PMID: 28544529 Hoang D, Broer N, Sosa JA, Abitbol N, Yao X, Li F, Rivera-Molina F, Toomre DK, Roman SA, Sue G, Kim S, Li AY, Callender GG, Simpson C, Narayan D: Leptin Is Produced by Parathyroid Glands and Stimulates Parathyroid Hormone Secretion. Ann Surg. 2016 Sep 8; 2016 Sep 8. PMID: 27611607 Deng Y, Rivera-Molina FE, Toomre DK, Burd CG: Sphingomyelin is sorted at the trans Golgi network into a distinct class of secretory vesicle. Proc Natl Acad Sci U S A. 2016 Jun 14; 2016 May 31. PMID: 27247384 Bottanelli F, Kromann EB, Allgeyer ES, Erdmann RS, Wood Baguley S, Sirinakis G, Schepartz A, Baddeley D, Toomre DK, Rothman JE, Bewersdorf J: Two-colour live-cell nanoscale imaging of intracellular targets. Nat Commun. 2016 Mar 4; 2016 Mar 4. PMID: 26940217 Idevall-Hagren O, Dickson EJ, Hille B, Toomre DK, De Camilli P: Optogenetic control of phosphoinositide metabolism. Proc Natl Acad Sci U S A. 2012 Aug 28; 2012 Jul 30. PMID: 22847441 Arasaki K, Toomre DK, Roy CR: The Legionella pneumophila effector DrrA is sufficient to stimulate SNARE-dependent membrane fusion. Cell Host Microbe. 2012 Jan 19. PMID: 22264512 Xu Y, Melia TJ, Toomre DK: Using light to see and control membrane traffic. Curr Opin Chem Biol. 2011 Dec; 2011 Nov 10. PMID: 22079055 Xu Y, Rubin BR, Orme CM, Karpikov A, Yu C, Bogan JS, Toomre DK: Dual-mode of insulin action controls GLUT4 vesicle exocytosis. J Cell Biol. 2011 May 16; 2011 May 9. PMID: 21555461 Liang L, Shen H, De Camilli P, Toomre DK, Duncan JS: An expectation maximization based method for subcellular particle tracking using multi-angle TIRF microscopy. Med Image Comput Comput Assist Interv. 2011. PMID: 22003671 Goss JW, Toomre DK: Both daughter cells traffic and exocytose membrane at the cleavage furrow during mammalian cytokinesis. J Cell Biol. 2008 Jun 30; 2008 Jun 23. PMID: 18573914 Iwakiri Y, Satoh A, Chatterjee S, Toomre DK, Chalouni CM, Fulton D, Groszmann RJ, Shah VH, Sessa WC: Nitric oxide synthase generates nitric oxide locally to regulate compartmentalized protein S-nitrosylation and protein trafficking. Proc Natl Acad Sci U S A. 2006 Dec 26; 2006 Dec 14. PMID: 17170139 Murata T, Delprato A, Ingmundson A, Toomre DK, Lambright DG, Roy CR: The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor. Nat Cell Biol. 2006 Sep; 2006 Aug 13. PMID: 16906144