个人简介
PhD University of Tokyo (2000)
Postdoctoral fellowship UCSF
研究领域
Biochemistry; Brain; Electrophysiology; Molecular Biology; Synaptic Transmission; Physiology
近期论文
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CaMKII phosphorylation of TARPγ-8 is a mediator of LTP and learning and memory.
Park J, Chavez AE, Mineur YS, Morimoto-Tomita M, Lutzu S, Kim KS, Picciotto MR, Castillo PE, and Tomita S. CaMKII phosphorylation of TARPγ-8 is a mediator of LTP and learning and memory. Neuron, 92:75-83, 2016
Distinct subunit domains govern synaptic stability and specificity of the kainate receptor.
Straub C, Noam Y, Nomura T, Yamasaki M, Yan D, Fernandes HB, Zhang P, Howe JR, Watanabe M, Contractor A, and Tomita S. Distinct subunit domains govern synaptic stability and specificity of the kainate receptor. Cell Report, 16:531-544, 2016
Synaptic localization of neurotransmitter receptors: comparing mechanisms for AMPA and GABAA receptors.
Martenson JS, and Tomita S. Synaptic localization of neurotransmitter receptors: comparing mechanisms for AMPA and GABAA receptors. Current Opinion in Pharmacology, 20:102-108, 2015.
Homeostatic control of synaptic transmission by distinct glutamate receptors
Yan D, Yamasaki M, Straub C, Watanabe M, and Tomita S. Homeostatic control of synaptic transmission by distinct glutamate receptors. Neuron, 78:687-399, 2013
Cornichons control ER export of AMPA receptors to regulate synaptic excitability
Brockie PJ, Jensen M, Mellem JE, Jensen E, Yamasaki T, Wang R, Maxfield D, Thacker C, Hoerndli F, Dunn PJ, Tomita S, Madsen DM, Maricq AV. Cornichons control ER export of AMPA receptors to regulate synaptic excitability. Neuron, 80:129-142, 2013
PDZ binding of TARPγ-8 controls synaptic transmission, but not synaptic plasticity.
Sumioka A, Brown T, Kato AS, Bredt DS, Kauer JA, and Tomita S. PDZ binding of TARP?-8 controls synaptic transmission, but not synaptic plasticity. Nature Neurosci., 14:1410-1412, 2011
Unique functions of kainate receptors in the brain are determined by the auxiliary subunit Neto1
Straub C, Hunt DL, Yamasaki M, Kim KS, Watanabe M, Castillo PE, and Tomita S. Unique functions of kainate receptors in the brain are determined by the auxiliary subunit Neto1. Nature Neurosci., 14, 866-873, 2011
Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins
Kato AS, Gill MB, Ho MT, Yu H, Tu Y, Siuda ER, Wang H, Qian YW, Nisenbaum ES, Tomita S, and Bredt DS. Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins. Neuron, 68, 1082-1096, 2010
phosphorylation regulates synaptic AMPA receptors through lipid bilayers
Sumioka A, Yan D, Tomita S. TARP phosphorylation regulates synaptic AMPA receptors through lipid bilayers. Neuron, 66:755-67, 2010.
Novel transmembrane accessory subunit modulates kainate-type glutamate receptors Zhang W, St-Gelais F, Grabner CP, Trinidad JC, Sumioka A, Morimoto-Tomita M, Kim KS, Straub C, Burlingame AL, Howe JR, Tomita S. Novel transmembrane accessory subunit modulates kainate-type glutamate receptors. Neuron, 61:385-96, 2009.
Auto-inactivation of neuronal AMPA receptors via glutamate-regulated TARP interaction
Morimoto-Tomita M, Zhang W, Straub C, Cho CH, Kim KS, Howe JR, Tomita S. Auto-inactivation of neuronal AMPA receptors via glutamate-regulated TARP interaction. Neuron, 61:101-12, 2009.
Two families of TARP isoforms that have distinct effects on the kinetic properties of AMPA receptors and synaptic currents
Cho CH, St-Gelais F, Zhang W, Tomita S, Howe JR. Two families of TARP isoforms that have distinct effects on the kinetic properties of AMPA receptors and synaptic currents. Neuron, 55:890-904, 2007.