Sung, Patrick - Yale University - Biological & Biomedical Sciences

个人简介

DPhil University of Oxford (1985) BS University of Liverpool (1981) Postdoctoral Fellow University of Rochester

研究领域

Biochemistry; Biophysics; DNA Repair; Radiation Oncology; Homologous Recombination; DNA End-Joining Repair

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Dray E, Etchin J, Wiese C, Saro D, Williams GJ, Hammel M, Yu X, Galkin VE, Liu D, Tsai MS, Sy SM, Schild D, Egelman E, Chen J, Sung P.Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Nat Struct Mol Biol. 2010 Oct;17(10):1255-9. Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae. Niu H, Chung WH, Zhu Z, Kwon Y, Zhao W, Chi P, Prakash R, Seong C, Liu D, Lu L, Ira G, Sung P.Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae. Nature. 2010 Sep 2;467(7311):108-11. FANCI binds branched DNA and is mono-ubiquitinated by UBE2T-FANCL. Longerich S, San Filippo J, Liu D, Sung P. FANCI binds branched DNA and is mono-ubiquitinated by UBE2T-FANCL. J Biol Chem. 2009 Jul 18. Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination. Prakash R, Satory D, Dray E, Papusha A, Scheller J, Kramer W, Krejci L, Klein H, Haber JE, Sung P, Ira G. Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination. Genes Dev. 2009 Jan 123(1):67-79. A double Holliday junction dissolvasome comprising BLM, topoisomerase IIIalpha, and BLAP75. Raynard, S., Bussen, W., and Sung, P. (2006). A double Holliday junction dissolvasome comprising BLM, topoisomerase IIIalpha, and BLAP75. J. Biol. Chem. 281:13861-13864. Human meiotic recombinase Dmc1 promotes ATP-dependent homologous DNA strand exchange. Sehorn, M.G., Sigurdsson, S., Bussen, W., Unger, V.M., and Sung, P. (2004). Human meiotic recombinase Dmc1 promotes ATP-dependent homologous DNA strand exchange. Nature 429:433-437.