Pereira, Joao Pedro - Yale University - Biological & Biomedical Sciences

个人简介

PhD University of Porto, Portugal (2004) MS DeMontfort University (1997)

研究领域

B-Lymphocytes; Bone Marrow; Hematopoiesis; Immune System; Stromal Cells

近期论文

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CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow. Beck TC, Gomes AC, Cyster JG, and Pereira JP. CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow. J Exp Med. 2014 Nov 17. EBI2 mediates B cell segregation between the outer and centre follicle. Pereira JP, Kelly LM, Xu Y, Cyster JG. EBI2 mediates B cell segregation between the outer and centre follicle. Nature. 2009 Aug 27;460(7259):1122-6. Epub 2009 Jul 13. Cannabinoid receptor 2 mediates the retention of immature B cells in bone marrow sinusoids. Pereira JP, An J, Xu Y, Huang Y, Cyster JG. Cannabinoid receptor 2 mediates the retention of immature B cells in bone marrow sinusoids. Nat Immunol. 2009 Apr 10(4):403-11. Oxysterols and EBI2 guide osteoclast precursors to the endosteum and regulate bone mass homeostasis. Nevius E, Pinho F, Dhodapkar M, Jin H, Nadrah K, Horowitz M, Kikuta J, Ishii M, and Pereira JP. Oxysterols and EBI2 guide osteoclast precursors to the endosteum and regulate bone mass homeostasis. J. Exp. Med. Oct 5. Immature B cell egress from bone marrow is SOCS3 independent. Nadrah K, Beck T, and Pereira JP. Immature B cell egress from bone marrow is SOCS3 independent. PLOS One 2015 Aug 14 Monoallelic expression of the murine gene encoding Toll-like receptor 4. Pereira JP, Girard R, Chaby R, Cumano A, Vieira P. Monoallelic expression of the murine gene encoding Toll-like receptor 4. Nat Immunol. 2003 May;4(5):464-70. Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients. Schwab SR, Pereira JP, Matloubian M, Xu Y, Huang Y, Cyster JG. Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients. Science. 2005 Sep 9;309(5741):1735-9. Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate. Pappu R, Schwab SR, Cornelissen I, Pereira JP, Regard JB, Xu Y, Camerer E, Zheng YW, Huang Y, Cyster JG, Coughlin SR. Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate. Science. 2007 Apr 13;316(5822):295-8. T-bet dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. Jenne CN, Enders A, Rivera R, Watson SR, Bankovich AJ, Pereira JP, Xu Y, Beilke JN, Reiner SL, Roots CM, Goodnow CC, Lanier LL, Cyster JG, and Chuns J. T-bet dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. J. Exp. Med. 2009. Oct 26;206 (11):2469-81. A role for S1P and S1P1 in immature-B cell egress from the mouse bone marrow. Pereira JP, Xu Y, Cyster JG. A role for S1P and S1P1 in immature-B cell egress from the mouse bone marrow. PloS One. 2010. Feb 18;5(2):e9277. CpG inhibits pro-B cell expansion through a cathepsin B-dependent mechanism. Lalanne AI, Moraga I, Hao Y, Pereira JP, Alves NL, Huntington ND, Freitas AA, Cumano A and Vieira P. CpG inhibits pro-B cell expansion through a cathepsin B-dependent mechanism. J. Immunol. 2010. May 15;184(10):5678-85. Finding the right niche: B cell migration in the early phases of T-dependent antibody responses. Pereira JP, Kelly LM, Cyster JG. Finding the right niche: B cell migration in the early phases of T-dependent antibody responses. Int. Immunol. 2010. Jun;22(6):413-9. Oxysterols direct immune cell migration through EBI2.