Park, In-Hyun - Yale University - Biological & Biomedical Sciences

个人简介

PhD University of Illinois at Urbana-Champaign (2005) MS Seoul National Univeristy (1999) BS Seoul National University (1994) Post-doc Fellow Harvard Medical School

研究领域

Cells; Central Nervous System Diseases; Nervous System; Stem Cells; Pluripotent Stem Cells; Embryonic Stem Cells; Induced Pluripotent Stem Cells; Neural Stem Cells; Psychiatry and Psychology

近期论文

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Transcriptome Signature and Regulation in Human Somatic Cell Reprogramming. Tanaka, Y., Hysolli, E., J. Su, Y. Xiang, K-.Y. Kim, M. Zhong, Y. Li, K Heydari, G. Euskirchen, M. P. Snyder, X. Pan, S. M. Weissman, and I.-H. Park (2015) Transcriptome Signature and Regulation in Human Somatic Cell Reprogramming. Stem Cell Reports, 4:1125-39. X Chromosome of Female Cells Shows Dynamic Changes in Status during Human Somatic Cell Reprogramming. Kim, K.-Y., E. Hysolli, Y. Tanaka, B. Wang, Y.-W. Jung, X. Pan, S. M. Weissman, and I.-H. Park (2014) X Chromosome of Female Cells Shows Dynamic Changes in Status during Human Somatic Cell Reprogramming. Stem Cell Reports, 2:896-909. Transcriptional regulation in pluripotent stem cells by methyl CpG-binding protein 2 (MeCP2). Tanaka, Y., K. Y. Kim, M. Zhong, X. Pan, S. M. Weissman, and I. H. Park (2014) Transcriptional regulation in pluripotent stem cells by methyl CpG-binding protein 2 (MeCP2). Hum Mol Genet, 23:1045-55. Pluripotent stem cell models of shwachman-diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction. Tulpule, A., J. M. Kelley, M. W. Lensch, J. McPherson, I. H. Park, O. Hartung, T. Nakamura, T. M. Schlaeger, A. Shimamura and G. Q. Daley (2013). Pluripotent stem cell models of shwachman-diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction. Cell Stem Cell 12: 727-736. Cellular reprogramming: a novel tool for investigating autism spectrum disorders. Kim, K. Y., Y. W. Jung, G. J. Sullivan, L. Chung and I. H. Park (2012). Cellular reprogramming: a novel tool for investigating autism spectrum disorders. Trends Mol Med 18: 463-471. Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome. Kun-Yong Kim, Eriona Hysolli, In-Hyun Park. Neuronal maturation defect in induced pluripotent stem cells from Rett syndrome patients. Proc. Natl. Acad. Sci. 2011;108:14169-14174. (PMC3161557) Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients. Agarwal, S., Y. H. Loh, E. M. McLoughlin, J. Huang, I. H. Park, J. D. Miller, H. Huo, M. Okuka, R. M. Dos Reis, S. Loewer, H. H. Ng, D. L. Keefe, et al. (2010). Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients. Nature 464: 292-296. Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells. Elayne M Chan*, Sutheera Ratanasirintrawoot*, In-Hyun Park*, Hongguang Huo, Philip D Manos, Junsung Rho, Yuin-Han Loh George Q. Daley and Thorsten M. Schlaeger (2009) Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells. Nature Biotechnology. 27:1033-1037. (* contributed equally) Hypo- and Hypermethylation of Tissue- and Cancer-related CpG Island Shores in Human Induced Pluripotent Stem (iPS) Cells. Akiko Doi*, In-Hyun Park*, Bo Wen*, Peter Murakami, Dr. Rafael Irizarry, Brian Herb, Sabine Loewer, Thorsten Schlaeger, Justine Miller, Junsung Rho, George Q. Daley, Andrew P. Feinberg (2009), Hypo- and Hypermethylation of Tissue- and Cancer-related CpG Island Shores in Human Induced Pluripotent Stem (iPS) Cells. Nature Genetics. 41:1350-1353. (* contributed equally) Disease-specific induced pluripotent stem cells. In-Hyun Park, Natasha Arora , Hongguang Huo, Nimet Maherali, Tim Ahfeldt, Akiko Shimamura, M. William Lensch, Chad Cowan, Konrad Hochedlinger and George Q Daley (2008) Disease-specific induced pluripotent stem cells. Cell, 134:877-886.