Palm, Noah Wolcott - Yale University - Biological & Biomedical Sciences

个人简介

Noah W. Palm is an Assistant Professor of Immunobiology and a member of the Human and Translational Immunology Program at the Yale University School of Medicine. His laboratory focuses on illuminating the myriad interactions between the immune system and the gut microbiota in health and disease. Dr. Palm performed his doctoral work with Ruslan Medzhitov and his postdoctoral work with Richard Flavell, both at Yale University. PhD Yale University, Immunobiology (2011) BA Macalester College, Biology (2004) Postdoctoral Fellowship Yale University School of Medicine

研究领域

Allergy and Immunology; Gastrointestinal Diseases; Homeostasis; Humans; Inflammation; Microbiology; Microbiota

近期论文

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Immune-microbiota interactions in health and disease. Palm NW*, de Zoete MR*, Flavell RA. Immune-microbiota interactions in health and disease. Clinical Immunology. 2015 Jun 30. Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease. Palm NW*, de Zoete MR*, Cullen TW, Barry NA, Stefanowski J, Hao L, Degnan PH, Hu J, Peter I, Zhang W, Ruggiero E, Cho JH, Goodman AL, Flavell RA. Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease. Cell. 2014. 158: 1000-10. Inflammasomes and intestinal homeostasis: regulating and connecting infection, inflammation and the microbiota. Gagliani N*, Palm NW*, de Zoete MR*, Flavell RA. Inflammasomes and intestinal homeostasis: regulating and connecting infection, inflammation and the microbiota. Int Immunol. 2014. 26: 495-499. Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity. Palm NW*, Rosenstein RK*, Yu S, Schenten DD, Florsheim E, Medzhitov R. Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity. Immunity. 2013. 39: 976-85. Role of the inflammasome in defense against venoms. Palm NW, Medzhitov R. Role of the inflammasome in defense against venoms. Proc. Natl. Acad. Sci. 2013. 110: 1809-1814. Allergic Host Defenses. Palm NW*, Rosenstein RK*, Medzhitov R. Allergic Host Defenses. Nature. 2012. 484: 464-72. Rice TA, Palm NW: Tummy Time: The Infant Microbiota-IgA Connection. Cell Host Microbe. 2016 Jul 13. PMID: 27414495 Costa FR, Françozo MC, de Oliveira GG, Ignacio A, Castoldi A, Zamboni DS, Ramos SG, Câmara NO, de Zoete MR, Palm NW, Flavell RA, Silva JS, Carlos D: Gut microbiota translocation to the pancreatic lymph nodes triggers NOD2 activation and contributes to T1D onset. J Exp Med. 2016 Jun 27; 2016 Jun 20. PMID: 27325889 Nowarski R, Jackson R, Gagliani N, de Zoete MR, Palm NW, Bailis W, Low JS, Harman CC, Graham M, Elinav E, Flavell RA: Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis. Cell. 2015 Dec 3. PMID: 26638073 Palm NW, de Zoete MR, Flavell RA: Immune-microbiota interactions in health and disease. Clin Immunol. 2015 Aug; 2015 Jun 30. PMID: 26141651 Gagliani N, Amezcua Vesely MC, Iseppon A, Brockmann L, Xu H, Palm NW, de Zoete MR, Licona-Limón P, Paiva RS, Ching T, Weaver C, Zi X, Pan X, Fan R, Garmire LX, Cotton MJ, Drier Y, Bernstein B, Geginat J, Stockinger B, Esplugues E, Huber S, Flavell RA: Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation. Nature. 2015 Jul 9; 2015 Apr 29. PMID: 25924064 de Zoete MR, Palm NW, Zhu S, Flavell RA: Inflammasomes. Cold Spring Harb Perspect Biol. 2014 Oct 16; 2014 Oct 16. PMID: 25324215 Gagliani N, Palm NW, de Zoete MR, Flavell RA: Inflammasomes and intestinal homeostasis: regulating and connecting infection, inflammation and the microbiota. Int Immunol. 2014 Sep; 2014 Jun 19. PMID: 24948595 Palm NW, de Zoete MR, Cullen TW, Barry NA, Stefanowski J, Hao L, Degnan PH, Hu J, Peter I, Zhang W, Ruggiero E, Cho JH, Goodman AL, Flavell RA: Immunoglobulin A coating identifies colitogenic bacteria in inflammatory bowel disease. Cell. 2014 Aug 28. PMID: 25171403 Palm NW, Rosenstein RK, Yu S, Schenten DD, Florsheim E, Medzhitov R: Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity. Immunity. 2013 Nov 14; 2013 Oct 24. PMID: 24210353 Licona-Limón P, Kim LK, Palm NW, Flavell RA: TH2, allergy and group 2 innate lymphoid cells. Nat Immunol. 2013 Jun. PMID: 23685824 Palm NW, Medzhitov R: Role of the inflammasome in defense against venoms. Proc Natl Acad Sci U S A. 2013 Jan 29; 2013 Jan 7. PMID: 23297192 Palm NW, Rosenstein RK, Medzhitov R: Allergic host defences. Nature. 2012 Apr 25; 2012 Apr 25. PMID: 22538607 Brodsky IE, Palm NW, Sadanand S, Ryndak MB, Sutterwala FS, Flavell RA, Bliska JB, Medzhitov R: A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system. Cell Host Microbe. 2010 May 20. PMID: 20478539