Paintsil, Elijah - Yale University - Biological & Biomedical Sciences

个人简介

The Paintsil laboratory focuses on increasing our understanding of the host determinants of individual differences in response to antiretroviral therapy; biomarkers and pathogenesis of increasing incidence of cancers in HIV treatment-experienced individuals. MBChB Ghana Medical School (1992) Fellow Yale University School of Medicine Resident Lincoln Medical Center, Bronx, NY Intern Lincoln Medical Center, Bronx, NY Intern Korle-Bu Teaching Hospital, Accra, Ghana

研究领域

Brazil; Ghana; Hepatitis C; HIV; Pediatrics; Pharmacology; Molecular Epidemiology; HIV Reverse Transcriptase; Infectious Disease Medicine

近期论文

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Impact of Novel HIV-1 Reverse Transcriptase Mutations, P119S and T165A on 4'-ethynylthymidine Analog Resistance Profile. Yang G, Paintsil E, Dutschman GE, Grill SP, Wang CJ, Wang J, Tanaka H, Hamasaki T, Baba M, Cheng YC. Impact of Novel HIV-1 Reverse Transcriptase Mutations, P119S and T165A on 4'-ethynylthymidine Analog Resistance Profile. Antimicrob Agents Chemother. 2009 Aug 24 Comparative Study of the Persistence of Anti-HIV Activity of Deoxynucleoside HIV Reverse Transcriptase Inhibitors after Removal from Culture. Elijah Paintsil, Susan P. Grill, Ginger E. Dutschman, and Yung-Chi Cheng. 2009. Comparative Study of the Persistence of Anti-HIV Activity of Deoxynucleoside HIV Reverse Transcriptase Inhibitors after Removal from Culture. AIDS Res Ther. 2009 Apr 22;6:5. Hepatitis C virus infection among drug injectors in St Petersburg, Russia: social and molecular epidemiology of an endemic infection. Paintsil E, Verevochkin SV, Dukhovlinova E, Niccolai L, Barbour R, White E, Toussova OV, Alexander L, Kozlov AP, Heimer R. Hepatitis C virus infection among drug injectors in St Petersburg, Russia: social and molecular epidemiology of an endemic infection. Addiction. 2009 Nov;104(11):1881-90 Absolute CD4+ T-Lymphocyte Count as a Surrogate Marker of Pediatric HIV Disease Progression. Elijah Paintsil, Musie Ghebremichael, Sostena Romano, and Warren A. Andiman. 2008. Absolute CD4+ T-Lymphocyte Count as a Surrogate Marker of Pediatric HIV Disease Progression. Pediatr Infect Dis J. 2008 Jul;27(7):629-35. Intracellular Metabolism and Persistence of the Anti-Human Immunodeficiency Virus Activity of 2 ‘, 3 ‘-Didehydro-3 ‘-Deoxy-4 ‘- Ethynylthymidine, A Novel Thymidine Analog. Elijah Paintsil, Ginger E. Dutschman, Rong Hu, Susan P. Grill, Wing Lam, Masanori Baba, Hiromichi Tanaka, and Yung-Chi Cheng. 2007. Intracellular Metabolism and Persistence of the Anti-Human Immunodeficiency Virus Activity of 2 ‘, 3 ‘-Didehydro-3 ‘-Deoxy-4 ‘- Ethynylthymidine, A Novel Thymidine Analog. Antimicrob. Agents Chemother. 51:3870-3879 The Contribution of HIV Fitness to the evolution pattern of Reverse Transcriptase Inhibitor Resistance. Elijah Paintsil, Asa Margolis, Jennifer A Collins and Louis Alexander. 2006. The Contribution of HIV Fitness to the evolution pattern of Reverse Transcriptase Inhibitor Resistance. J. Med. Virol. 78:425-430 Nichols J, Steinmetz A, Paintsil E: Impact of HIV-Status Disclosure on Adherence to Antiretroviral Therapy Among HIV-Infected Children in Resource-Limited Settings: A Systematic Review. AIDS Behav. 2017 Jan. PMID: 27395433 Sam-Agudu NA, Paintsil E, Aliyu MH, Kwara A, Ogunsola F, Afrane YA, Onoka C, Awandare GA, Amponsah G, Cornelius LJ, Mendy G, Sturke R, Ghansah A, Siberry GK, Ezeanolue EE: Building Sustainable Local Capacity for Global Health Research in West Africa. Ann Glob Health. 2016 Nov - Dec. PMID: 28314488 Li M, Mislak AC, Foli Y, Agbosu E, Bose V, Bhandari S, Szymanski MR, Shumate CK, Yin YW, Anderson KS, Paintsil E: The DNA Polymerase Gamma R953C Mutant Is Associated with Antiretroviral Therapy-Induced Mitochondrial Toxicity. Antimicrob Agents Chemother. 2016 Sep; 2016 Aug 22. PMID: 27381400 Paintsil E, Martin R, Goldenthal A, Bhandari S, Andiman W, Ghebremichael M: Frequent Episodes of Detectable Viremia in HIV Treatment-Experienced Children is Associated with a Decline in CD4+ T-cells Over Time. J AIDS Clin Res. 2016 Apr; 2016 Apr 14. PMID: 27379199 Kukoyi O, Renner L, Powell J, Barry O, Prin M, Kusah J, Cong X, Paintsil E: Viral load monitoring and antiretroviral treatment outcomes in a pediatric HIV cohort in Ghana. BMC Infect Dis. 2016 Feb 3; 2016 Feb 3. PMID: 26843068 Hansen C, Paintsil E: Infectious Diseases of Poverty in Children: A Tale of Two Worlds. Pediatr Clin North Am. 2016 Feb. PMID: 26613688 Binka M, Paintsil E, Patel A, Lindenbach BD, Heimer R: Survival of Hepatitis C Virus in Syringes Is Dependent on the Design of the Syringe-Needle and Dead Space Volume. PLoS One. 2015; 2015 Nov 4. PMID: 26536599 Li M, Foli Y, Amakye NY, Klein T, Selvaraj S, Lu L, Paintsil E: Antiretroviral therapy-induced toxicity is associated with increased mRNA expression of telomerase. J Clin Pharmacol. 2015 Oct; 2015 May 28. PMID: 25903721 Reynolds NR, Ofori-Atta A, Lartey M, Renner L, Antwi S, Enimil A, Catlin AC, Fernando S, Kyriakides TC, Paintsil E: SANKOFA: a multisite collaboration on paediatric HIV disclosure in Ghana. AIDS. 2015 Jun. PMID: 26049537 Dukhovlinova E, Masharsky A, Toussova O, Verevochkin S, Solovyeva T, Meringof M, Paintsil E, White E, Barbour R, Heimer R, Kozlov A: Two Independent HIV Epidemics in Saint Petersburg, Russia Revealed by Molecular Epidemiology. AIDS Res Hum Retroviruses. 2015 Jun; 2015 Jan 5. PMID: 25417740 VanDeusen A, Paintsil E, Agyarko-Poku T, Long EF: Cost effectiveness of option B plus for prevention of mother-to-child transmission of HIV in resource-limited countries: evidence from Kumasi, Ghana. BMC Infect Dis. 2015 Mar 18; 2015 Mar 18. PMID: 25887574 Binka M, Paintsil E, Patel A, Lindenbach BD, Heimer R: Disinfection of syringes contaminated with hepatitis C virus by rinsing with household products. Open Forum Infect Dis. 2015 Jan; 2015 Feb 23. PMID: 26034767 Catlin AC, Fernando S, Gamage R, Renner L, Antwi S, Tettey JK, Amisah KA, Kyriakides T, Cong X, Reynolds NR, Paintsil E: Sankofa pediatric HIV disclosure intervention cyber data management: building capacity in a resource-limited setting and ensuring data quality. AIDS Care. 2015. PMID: 26616131