Nelson, Bryce - Yale University - Biological & Biomedical Sciences

个人简介

Bryce received his Ph.D. from Queens University in Canada in 2002 where he studied signal transduction using yeast. From there he moved up the evolutionary scale to flies, still in the field of signal transduction and innate immunity, before settling on phage display and synthetic antibodies in the lab of Sachdev Sidhu in Toronto in 2010. Bryce set up a lab in Cold Spring Harbor Laboratory in 2013 and served as director of antibodies and phage display before accepting a position at the Yale Cancer Biology Institute in 2015. PhD Queens University (2002)

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Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal region. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17832-7. doi: 10.1073/pnas.1317118110. Epub 2013 Oct 14. Complete list of publications http://www.ncbi.nlm.nih.gov/sites/myncbi/1-CmepLO6ijkC/bibliography/49294313/public/?sort=date&direction=ascending Schulz WL, Nelson BG, Felker DK, Durant TJ, Torres R: Evaluation of relational and NoSQL database architectures to manage genomic annotations. J Biomed Inform. 2016 Dec; 2016 Oct 31. PMID: 27810480 Fusar-Poli P, Cappucciati M, Borgwardt S, Woods SW, Addington J, Nelson B, Nieman DH, Stahl DR, Rutigliano G, Riecher-Rössler A, Simon AE, Mizuno M, Lee TY, Kwon JS, Lam MM, Perez J, Keri S, Amminger P, Metzler S, Kawohl W, Rössler W, Lee J, Labad J, Ziermans T, An SK, Liu CC, Woodberry KA, Braham A, Corcoran C, McGorry P, Yung AR, McGuire PK: Heterogeneity of Psychosis Risk Within Individuals at Clinical High Risk: A Meta-analytical Stratification. JAMA Psychiatry. 2016 Feb. PMID: 26719911 Sudmant PH, Rausch T, Gardner EJ, Handsaker RE, Abyzov A, Huddleston J, Zhang Y, Ye K, Jun G, Hsi-Yang Fritz M, Konkel MK, Malhotra A, Stütz AM, Shi X, Paolo Casale F, Chen J, Hormozdiari F, Dayama G, Chen K, Malig M, Chaisson MJ, Walter K, Meiers S, Kashin S, Garrison E, Auton A, Lam HY, Jasmine Mu X, Alkan C, Antaki D, Bae T, Cerveira E, Chines P, Chong Z, Clarke L, Dal E, Ding L, Emery S, Fan X, Gujral M, Kahveci F, Kidd JM, Kong Y, Lameijer EW, McCarthy S, Flicek P, Gibbs RA, Marth G, Mason CE, Menelaou A, Muzny DM, Nelson BJ, Noor A, Parrish NF, Pendleton M, Quitadamo A, Raeder B, Schadt EE, Romanovitch M, Schlattl A, Sebra R, Shabalin AA, Untergasser A, Walker JA, Wang M, Yu F, Zhang C, Zhang J, Zheng-Bradley X, Zhou W, Zichner T, Sebat J, Batzer MA, McCarroll SA, 1000 Genomes Project Consortium., Mills RE, Gerstein MB, Bashir A, Stegle O, Devine SE, Lee C, Eichler EE, Korbel JO: An integrated map of structural variation in 2,504 human genomes. Nature. 2015 Oct 1. PMID: 26432246 Nelson B, Naraine V, Patterson C, Rodrigo S: Prevalence of Congenital Malformations in Grenada. West Indian Med J. 2015 May 12; 2015 May 12. PMID: 26633136 Reshetnyak AV, Nelson B, Shi X, Boggon TJ, Pavlenco A, Mandel-Bausch EM, Tome F, Suzuki Y, Sidhu SS, Lax I, Schlessinger J: Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal region. Proc Natl Acad Sci U S A. 2013 Oct 29; 2013 Oct 14. PMID: 24127596 Wang Z, Oron E, Nelson B, Razis S, Ivanova N: Distinct lineage specification roles for NANOG, OCT4, and SOX2 in human embryonic stem cells. Cell Stem Cell. 2012 Apr 6. PMID: 22482508 Nelson BE, Mayer AR, Tseng PC, Schwartz PE: Experience with the intravenous totally implanted port in patients with gynecologic malignancies. Gynecol Oncol. 1994 Apr. PMID: 8175028 Nelson BE, Rose PG: Malignant pericardial effusion from squamous cell cancer of the cervix. J Surg Oncol. 1993 Mar. PMID: 8441281 Nelson BE, Rosenfield AT, Schwartz PE: Preoperative abdominopelvic computed tomographic prediction of optimal cytoreduction in epithelial ovarian carcinoma. J Clin Oncol. 1993 Jan. PMID: 8418230 Nelson BE, Carcangiu ML, Chambers JT: Intraabdominal hemorrhage with pulmonary large cell carcinoma metastatic to the ovary. Gynecol Oncol. 1992 Dec. PMID: 1335432 Mayer AR, Chambers SK, Graves E, Holm C, Tseng PC, Nelson BE, Schwartz PE: Ovarian cancer staging: does it require a gynecologic oncologist? Gynecol Oncol. 1992 Nov. PMID: 1468701