Morrow, Jon Stanley - Yale University - Biological & Biomedical Sciences

个人简介

MD Yale University (1976) PhD Indiana University School of Medicine (1974) Resident Yale-New Haven Hospital Fellow Yale University School of Medicine Board Certification AB of Pathology, Anatomic Pathology (1980)

研究领域

Autopsy; Computer-Assisted Instruction; Medical Informatics; Pathology; Spectrin; Telepathology

近期论文

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Sequential degradation of alphaII and betaII spectrin by calpain in glutamate or maitotoxin-stimulated cells. Glantz, S.B., Cianci, C.D., Iyer, R., Pradhan, D., Wang, K.K., and Morrow, J.S. (2007). Sequential degradation of alphaII and betaII spectrin by calpain in glutamate or maitotoxin-stimulated cells. Biochem. 46(2):502-13. Structure of the calmodulin alphaII-spectrin complex provides insight into the regulation of cell plasticity. Simonovic, M., Zhang, Z., Cianci, C.D., Steitz, T.A., and Morrow, J,S. (2006). Structure of the calmodulin alphaII-spectrin complex provides insight into the regulation of cell plasticity. J. Biol. Chem. 281(45):34333-40. TGFbeta induces caspase 3 independent cleavage of alpha II spectrin (alpha-fodrin) coincident with apoptosis. Brown, T. L., Patil, S., Cianci, C. D., Morrow, J. S. and Howe, P. H. 1999. TGFbeta induces caspase 3 independent cleavage of alpha II spectrin (alpha-fodrin) coincident with apoptosis. J. Biol. Chem. in Pathology Exclusion of the stomatin, a-adducin and b-adducin loci in a large kindred with dehydrated hereditary stomatocytosis. Innes, D. S., Sinard, J. H., Gilligan, D. M., Snyder, L. M., Gallagher, P. G. and Morrow, J. S. 1998. Exclusion of the stomatin, a-adducin and b-adducin loci in a large kindred with dehydrated hereditary stomatocytosis. Am. J. Hematology 60:72-4. Utilization of an 86 bp exon generates a novel adducin isoform (b4) lacking the MARCKS homology domain. Sinard, J. H., Stewart, G. W., Argent, A. C., Stabach, P. R., Gilligan, D. M. and Morrow, J. S. 1998. Utilization of an 86 bp exon generates a novel adducin isoform (b4) lacking the MARCKS homology domain. Biochim Biophys Acta 1396:57-66. Simultaneous degradation of aII and bII spectrin by caspase 3 (CPP32) in apoptotic cells. Wang, K. K. W., Posmantur, R., Nath, R., McGinnis, K., Whitton, M., Talanian, R. V., Glantz, S. B. and Morrow, J. S. 1998. Simultaneous degradation of aII and bII spectrin by caspase 3 (CPP32) in apoptotic cells. J. Biol. Chem 273:22490-22497. Zhang, Z., Devarajan, P., Dorfman, A. L. and Morrow, J. S. 1998. Structure of the Ankyrin Binding Domain of a-Na,K-ATPase. J. Biol. Chem 273:18681-18684. A widely expressed betaIII spectrin associated with Golgi and cytoplasmic vesicles. Stankewich, M. C., Tse, W. T., Peters, L. L., Ch’ng, Y., John, K. M., Stabach, P. R., Devarajan, P., Morrow, J. S. and Lux, S. E. 1998. A widely expressed betaIII spectrin associated with Golgi and cytoplasmic vesicles. Proc. Natl. Acad. Sci (USA) 95:14158-14163. Helou E, Grant M, Landry M, Wu X, Morrow JS, Malinis MF: Fatal case of cutaneous sparing, oro-laryngeal zoster in a renal transplant recipient. Transpl Infect Dis. 2017 Apr 12; 2017 Apr 12. PMID: 28401625 Kim JH, Kwon SJ, Stankewich MC, Huh GY, Glantz SB, Morrow JS: Reactive protoplasmic and fibrous astrocytes contain high levels of calpain-cleaved alpha 2 spectrin. Exp Mol Pathol. 2016 Feb; 2015 Nov 10. PMID: 26551084 Stankewich MC, Moeckel GW, Ji L, Ardito T, Morrow JS: Isoforms of Spectrin and Ankyrin Reflect the Functional Topography of the Mouse Kidney. PLoS One. 2016; 2016 Jan 4. PMID: 26727517 Vyas M, Zhang X, Morrow JS, Jain D, Salem RR, West AB: Focal hepatic glycogenosis associated with metastatic insulinoma presenting as mass lesions. Pathol Res Pract. 2016 Jan; 2015 Nov 26. PMID: 26627264 Stankewich MC, Cianci CD, Stabach PR, Ji L, Nath A, Morrow JS: Cell organization, growth, and neural and cardiac development require αII-spectrin. J Cell Sci. 2011 Dec 1; 2011 Dec 8. PMID: 22159418 Stankewich MC, Gwynn B, Ardito T, Ji L, Kim J, Robledo RF, Lux SE, Peters LL, Morrow JS: Targeted deletion of betaIII spectrin impairs synaptogenesis and generates ataxic and seizure phenotypes. Proc Natl Acad Sci U S A. 2010 Mar 30; 2010 Mar 15. PMID: 20231455 Stabach PR, Simonović I, Ranieri MA, Aboodi MS, Steitz TA, Simonović M, Morrow JS: The structure of the ankyrin-binding site of beta-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties. Blood. 2009 May 28; 2009 Jan 23. PMID: 19168783 Stabach PR, Devarajan P, Stankewich MC, Bannykh S, Morrow JS: Ankyrin facilitates intracellular trafficking of alpha1-Na+-K+-ATPase in polarized cells. Am J Physiol Cell Physiol. 2008 Nov; 2008 Sep 3. PMID: 18768923 Sangerman J, Maksimova Y, Edelman EJ, Morrow JS, Forget BG, Gallagher PG: Ankyrin-linked hereditary spherocytosis in an African-American kindred. Am J Hematol. 2008 Oct. PMID: 18704959 Glantz SB, Cianci CD, Iyer R, Pradhan D, Wang KK, Morrow JS: Sequential degradation of alphaII and betaII spectrin by calpain in glutamate or maitotoxin-stimulated cells. Biochemistry. 2007 Jan 16. PMID: 17209560