Loria, J Patrick - Yale University - Biological & Biomedical Sciences

个人简介

PhD University of Notre Dame, Biochemistry (1996) BS George Washington University, Chemistry (1990) NIH Postdoctoral Fellow Columbia University

研究领域

Biochemistry; Biophysics; Chemistry; Molecular Biology; Magnetic Resonance Spectroscopy; Protein Folding

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

The role of loop-loop interactions in coordinating motions and enzymatic function in triosephosphate isomerase. Wang, Y., Berlow, R., and J.P. Loria. (2009). The role of loop-loop interactions in coordinating motions and enzymatic function in triosephosphate isomerase Biochemistry. 48,4548-4556. The Mechanism of Rate-limiting Motions in Enzyme Function. Eric D. Watt, Hiroko Shimada, Evgenii L. Kovrigin, and J.P. Loria. (2007). The Mechanism of Rate-limiting Motions in Enzyme Function. PNAS 104, 11981-11986. Lisi GP, East KW, Batista VS, Loria JP: Altering the allosteric pathway in IGPS suppresses millisecond motions and catalytic activity. Proc Natl Acad Sci U S A. 2017 Apr 25; 2017 Apr 10. PMID: 28396388 Lipchock JM, Hendrickson HP, Douglas BB, Bird KE, Ginther PS, Rivalta I, Ten NS, Batista VS, Loria JP: Characterization of Protein Tyrosine Phosphatase 1B Inhibition by Chlorogenic Acid and Cichoric Acid. Biochemistry. 2017 Jan 10; 2016 Dec 27. PMID: 27959494 Lisi GP, Manley GA, Hendrickson H, Rivalta I, Batista VS, Loria JP: Dissecting Dynamic Allosteric Pathways Using Chemically Related Small-Molecule Activators. Structure. 2016 Jul 6; 2016 May 26. PMID: 27238967 Lisi GP, Loria JP: Solution NMR Spectroscopy for the Study of Enzyme Allostery. Chem Rev. 2016 Jun 8; 2016 Jan 6. PMID: 26734986 Lisi GP, Loria JP: Using NMR spectroscopy to elucidate the role of molecular motions in enzyme function. Prog Nucl Magn Reson Spectrosc. 2016 Feb; 2015 Dec 7. PMID: 26952190 Moscato B, Swain M, Loria JP: Induced Fit in the Selection of Correct versus Incorrect Nucleotides by DNA Polymerase β. Biochemistry. 2016 Jan 19; 2015 Dec 30. PMID: 26678253 Liptak C, Loria JP: Movement and specificity in a modular DNA binding protein. Structure. 2015 Jun 2. PMID: 26039344 Khirich G, Loria JP: Complexity of protein energy landscapes studied by solution NMR relaxation dispersion experiments. J Phys Chem B. 2015 Mar 5; 2015 Feb 20. PMID: 25680027 Ho J, Newcomer MB, Ragain CM, Gascon JA, Batista ER, Loria JP, Batista VS: MoD-QM/MM Structural Refinement Method: Characterization of Hydrogen Bonding in the Oxytricha nova G-Quadruplex. J Chem Theory Comput. 2014 Nov 11; 2014 Oct 8. PMID: 26584390 Whittier SK, Loria JP: ¹H, ¹⁵N, and ¹³C backbone resonance assignments for the Yersinia protein tyrosine phosphatase YopH. Biomol NMR Assign. 2014 Oct; 2013 Sep 12. PMID: 24026965 Frey MA, Sethna ZM, Manley GA, Sengupta S, Zilm KW, Loria JP, Barrett SE: Accelerating multidimensional NMR and MRI experiments using iterated maps. J Magn Reson. 2013 Dec; 2013 Sep 21. PMID: 24184710 Wong M, Khirich G, Loria JP: What's in your buffer? Solute altered millisecond motions detected by solution NMR. Biochemistry. 2013 Sep 17; 2013 Aug 30. PMID: 23991940 Whittier SK, Hengge AC, Loria JP: Conformational motions regulate phosphoryl transfer in related protein tyrosine phosphatases. Science. 2013 Aug 23. PMID: 23970698 Fan C, Rajasekaran D, Syed MA, Leng L, Loria JP, Bhandari V, Bucala R, Lolis EJ: MIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrations. Proc Natl Acad Sci U S A. 2013 Jul 2; 2013 Jun 17. PMID: 23776208 Manley G, Rivalta I, Loria JP: Solution NMR and computational methods for understanding protein allostery. J Phys Chem B. 2013 Mar 21; 2013 Mar 12. PMID: 23445323 Berlow RB, Swain M, Dalal S, Sweasy JB, Loria JP: Substrate-dependent millisecond domain motions in DNA polymerase β. J Mol Biol. 2012 Jun 8; 2012 Mar 23. PMID: 22446382 Rivalta I, Sultan MM, Lee NS, Manley GA, Loria JP, Batista VS: Allosteric pathways in imidazole glycerol phosphate synthase. Proc Natl Acad Sci U S A. 2012 May 29; 2012 May 14. PMID: 22586084 Manley G, Loria JP: NMR insights into protein allostery. Arch Biochem Biophys. 2012 Mar 15; 2011 Dec 16. PMID: 22198279 Watt ED, Rivalta I, Whittier SK, Batista VS, Loria JP: Reengineering rate-limiting, millisecond enzyme motions by introduction of an unnatural amino acid. Biophys J. 2011 Jul 20. PMID: 21767494 Doucet N, Khirich G, Kovrigin EL, Loria JP: Alteration of hydrogen bonding in the vicinity of histidine 48 disrupts millisecond motions in RNase A. Biochemistry. 2011 Mar 15; 2011 Feb 10. PMID: 21250662 Lipchock JM, Loria JP: Nanometer propagation of millisecond motions in V-type allostery. Structure. 2010 Dec 8. PMID: 21134639