Kluger, Yuval - Yale University - Biological & Biomedical Sciences

个人简介

PhD Tel Aviv University (1993)

研究领域

Breast Neoplasms; Information Science; Pattern Recognition, Automated; Genetic Variation; Nevi and Melanomas; Genetic Structures; Mathematical Concepts

近期论文

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Ranking and combining multiple predictors without labeled data F. Parisi, F. Strino, B. Nadler, and Y. Kluger, "Ranking and combining multiple predictors without labeled data," PNAS, p. 201219097, 2014. TrAp: a Tree Approach for Fingerprinting Subclonal Tumor Composition Strino, F., Parisi, F., Micsinai, M., and Kluger,Y., TrAp: a Tree Approach for Fingerprinting Subclonal Tumor Composition, Nucleic Acids Research 2013; doi: 10.1093/nar/gkt641, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783191/ Arpeggio: Harmonic compression of ChIP-seq data reveals protein-chromatin interaction signatures Stanton, K., Parisi, F., Strino, F., Rabin, N., Asp, P. and Kluger,Y., Arpeggio: Harmonic compression of ChIP-seq data reveals protein-chromatin interaction signatures, Nucleic Acids Research 2013; doi: 10.1093/nar/gkt627 The RAG2 C-terminus and ATM control cleavage to limit the number of potential translocation substrates Chaumeil, J., Micsinai, M., Ntziachristos, P., Roth, D.B., Aifantis, I., Kluger, Y., Deriano, L., and Skok, J.A., The RAG2 C-terminus and ATM control cleavage to limit the number of potential translocation substrates, Nature Communications 4, Article number: 2231 doi:10.1038/ncomms3231 Picking ChIP-seq peak detectors for analyzing chromatin modification experiments M. Micsinai, F. Parisi, F. Strino, P. Asp, B. D. Dynlacht, and Y. Kluger, "Picking ChIP-seq peak detectors for analyzing chromatin modification experiments," Nucleic Acids Research, 2012 PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes Z. Gao, J. Zhang, R. Bonasio, F. Strino, A. Sawai, F. Parisi, Y. Kluger, and D. Reinberg, "PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes," Molecular Cell, vol. 45, pp. 344-356, 2012. VDA, a Method of Choosing a Better Algorithm with Fewer Validations F. Strino, F. Parisi, and Y. Kluger, "VDA, a Method of Choosing a Better Algorithm with Fewer Validations," PLoS ONE, vol. 6, p. e26074, 2011 Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies Parisi F., Ariyan S., Narayan D., Bacchiocchi A., Hoyt K., Cheng E., Xu F., Li P., Halaban R., and Kluger Y., Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies, BMC Genomics, doi:10.1186/1471-2164-12-230. PMID: 21569352 Genome-wide remodeling of the epigenetic landscape during myogenic differentiation. P. Asp, V. Vethantham, R. Blum, F. Parisi , C. Bowman, J. Cheng, M. Micsinai, Y. Kluger, and B.D. Dynlacht. Proc Natl Acad Sci U S A. 2011 May 31;108(22):E149-58. doi: 10.1073/pnas.1102223108. Epub 2011 May 5. Benefits of biomarker selection and clinico-pathological covariate inclusion in breast cancer prognostic models Parisi F, Gonzalez AM, Nadler Y, Camp RL, Rimm DL, Kluger HM, Kluger Y, Benefits of biomarker selection and clinico-pathological covariate inclusion in breast cancer prognostic models, Breast Cancer Research 2010, 12:R66 A role for mammalian Sin3 in permanent gene silencing. C. Van Oevelen, J. Wang, Asp P, Yan Q, Kaelin WG Jr, Y. Kluger*, and B.D. Dynlacht*. A role for mammalian Sin3 in permanent gene silencing. Molecular Cell 2008, 32(3) pp. 359 - 370 XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks Acosta-Alvear D, Zhou Y, Blais A, Tsikitis M, Lents NH, Arias C, Lennon CJ, Kluger Y, Dynlacht BD, XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks, Molecular Cell 2007 27 (1):53-66 Characterizing disease states from topological properties of transcriptional regulatory networks