个人简介
Dr. Irish obtained her Ph.D. from Harvard University, where she characterized the role of the DPP/TGFbeta signaling pathway in specifying dorsal-ventral polarity in the Drosophila embryo. After postdoctoral work investigating anterior-posterior patterning in Drosophila, she turned her attention to exploring patterning processes in the Arabidopsis flower. For a number of years she has focused on characterizing the genes and pathways regulating organogenesis and growth in the flower. She has also explored the extent to which these pathways are conserved across different flowering plant species. Using molecular, genetic and modeling approaches, her current research is centered on understanding how these processes are integrated in forming a petal, a simple laminar organ of few cell types, but whose form varies widely in different plant species.
PhD Harvard University, Cell and Developmental Biology (1986)
BA Wesleyan University, Biology (1980)
Postdoctoral Fellow Yale University
Postdoctoral Fellow Cambridge University
研究领域
Ecology; Biological Evolution; Genetics; Human Development; Molecular Biology; Developmental Biology; Arabidopsis
近期论文
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Gene networks controlling petal organogenesis
Huang T, Irish VF. 2015. Gene networks controlling petal organogenesis. J. Exp Bot. in press
Temporal Control of Plant Organ Growth by TCP Transcription Factors.
Huang T, Irish VF. 2015. Temporal Control of Plant Organ Growth by TCP Transcription Factors. Current Biology. 13:1765-1770
Natural variation identifies multiple loci controlling petal shape and size in Arabidopsis thaliana.
Abraham MC, Metheetrairut C, Irish VF. 2013. Natural variation identifies multiple loci controlling petal shape and size in Arabidopsis thaliana. PLoS One. 8:e56743
RBE controls microRNA164 expression to effect floral organogenesis.
Huang T, López-Giráldez F, Townsend JP, Irish VF. 2012. RBE controls microRNA164 expression to effect floral organogenesis. Development. 139:2161-9.
The flowering of Arabidopsis flower development
Irish VF. 2010. The flowering of Arabidopsis flower development. Plant Journal 61: 1014-1028
The Arabidopsis floral homeotic proteins APETALA3 and PISTILLATA negatively regulate the BANQUO genes implicated in light signaling
Mara CD, Huang T, Irish VF. 2010. The Arabidopsis floral homeotic proteins APETALA3 and PISTILLATA negatively regulate the BANQUO genes implicated in light signaling. The Plant Cell 22: 690-702.
An Arabidopsis F-box protein acts as a transcriptional cofactor to regulate floral development
Chae E, Tan Q. K-G, Hill TA, Irish VF. 2008. An Arabidopsis F-box protein acts as a transcriptional cofactor to regulate floral development. Development 135: 1235-1245
DeMartino G, Pan I, Emmanuel E, Levy AA, Irish VF. 2006. Functional analyses of two tomato APETALA3 genes demonstrate diversification in their roles in regulating flowering. The Plant Cell 18: 1833-1845.
Functional divergence within the APETALA3/ PISTILLATA floral homeotic gene lineages.
Lamb RS. Irish VF. 2003. Functional divergence within the APETALA3/ PISTILLATA floral homeotic gene lineages. Proc. Nat. Acad. Sci. 100: 6558-6563.
Evolution of genetic mechanisms controlling petal development.
Kramer, E.M. and V.F. Irish. 1999. Evolution of genetic mechanisms controlling petal development. Nature, 399: 144-148.