Hammarlund, Marc - Yale University - Biological & Biomedical Sciences

个人简介

Marc did his doctoral work with Erik Jorgensen, studying genetics and synaptic transmission. In his postdoc with Mike Bastiani he pioneered the study of axon regeneration in C. elegans and discovered the DLK regeneration pathway. PhD University of Utah (2003)

研究领域

Axons; Cell Biology; Nerve Regeneration; Gene Expression; Caenorhabditis elegans

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Inhibiting poly(ADP-ribosylation) improves axon regeneration Byrne AB, McWhirter RD, Sekine Y, Strittmatter SM, Miller DM, Hammarlund M: Inhibiting poly(ADP-ribosylation) improves axon regeneration. Elife. 2016 Oct 4; 2016 Oct 4. PMID: 27697151 Axon regeneration in C. elegans: Worming our way to mechanisms of axon regeneration Byrne AB, Hammarlund M: Axon regeneration in C. elegans: Worming our way to mechanisms of axon regeneration. Exp Neurol. 2016 Aug 26; 2016 Aug 26. PMID: 27569538 RNA ligation in neurons by RtcB inhibits axon regeneration. Kosmaczewski, S.G., Han, S.M., Han, B., Meyer, B., Baig, H.S., Athar, W., Lin_moore, A.T., Koelle, M.R., and Hammarlund, M. (2015). RNA ligation in neurons by RtcB inhibits axon regeneration. PNAS 11(27), 8451-6. Insulin/IGF1 Signaling Inhibits Age-Dependent Axon Regeneration. Byrne, A. B., Walradt, T., Gardner, K. E., Hubbert, A., Reinke, V., and Hammarlund, M. (2014). Insulin/IGF1 Signaling Inhibits Age-Dependent Axon Regeneration. Neuron 81, 1-13. Axon regeneration in C. elegans. Hammarlund, M. and Jin, Yishi. (2014). Axon regeneration in C. elegans. Current Opinion in Neurobiology 27, 199-207. Syndecan promotes axon regeneration by stabilizing growth cone migration. Edwards TJ, Hammarlund M. (2014) Syndecan promotes axon regeneration by stabilizing growth cone migration. Cell reports. 2014; 8(1):272-83. The RtcB RNA ligase is an essential component of the metazoan unfolded protein response. Kosmaczewski, S.G., Edwards, T.J., Han, S.M., Eckwahl, M.J., Meyer, B., Peach, S., Hesselberth, J., Wolin, S.L., and Hammarlund, M. (2014). The RtcB RNA ligase is an essential component of the metazoan unfolded protein response. EMBO Reports 15, 1278-85. A multi-channel device for high-density target-selective stimulation and long-term monitoring of cells and subcellular features in C. elegans. Lee H, Kim SA, Coakley S, Mugno P, Hammarlund M, et al. (2014) A multi-channel device for high-density target-selective stimulation and long-term monitoring of cells and subcellular features in C. elegans. Lab on a chip 14(23):4513-22. Bidirectional thermotaxis in Caenorhabditis elegans is mediated by distinct sensorimotor strategies driven by the AFD thermosensory neurons. Luo L, Cook N, Venkatachalam V, Martinez-Velazquez LA, Zhang X, et al. (2014) Bidirectional thermotaxis in Caenorhabditis elegans is mediated by distinct sensorimotor strategies driven by the AFD thermosensory neurons. PNAS 111(7):2776-81. Axon regeneration genes identified by RNAi screening in C. elegans. Nix P, Hammarlund M, Hauth L, Lachnit M, Jorgensen EM, et al. (2014). Axon regeneration genes identified by RNAi screening in C. elegans. The Journal of neuroscience 34(2):629-45. Neuron-specific feeding RNAi in C. elegans, and its use in a screen for essential genes required for GABA neuron function. Firnhaber, C. and Hammarlund, M. (2013). Neuron-specific feeding RNAi in C. elegans, and its use in a screen for essential genes required for GABA neuron function. PLoS Genetics 9(11): e1003921. Rapid and permanent neuronal inactivation in vivo via subcellular generation of reactive oxygen using KillerRed. Williams, D. C., El Bejjani, R., Ramirez, P. M., Coakley, S., Kim, S., Lee, H., Wen, Q., Samuel, A., Lu, H., Hilliard, M. A., and Hammarlund, M. (2013). Rapid and permanent neuronal inactivation in vivo via subcellular generation of reactive oxygen using KillerRed. Cell Reports 5, 553-63. Notch signaling inhibits axon regeneration.