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Choosing Cell Fate Through a Dynamic Cell Cycle Xinyue Chen , Amaleah Hartman and Shangqin Guo, Current Stem Cell Reports September 2015, Volume 1, Issue 3, pp 129-138
Non-stochastic reprogramming from a privileged somatic cell state.
Non-stochastic reprogramming from a privileged somatic cell state. Shangqin Guo (corresponding author), Xiaoyuan Zi, Vincent P. Schulz, Jijun Cheng, Mei Zhong, Sebastian H.J. Koochaki, Cynthia M. Megyola, Xinghua Pan, Kartoosh Heydari, Sherman M. Weissman, Patrick G. Gallagher, Diane S. Krause, Rong Fan and Jun Lu. Cell, online Jan 30th, 2014
An Extensive Network of TET2-Targeting MicroRNAs Regulates Malignant Hematopoiesis.
An Extensive Network of TET2-Targeting MicroRNAs Regulates Malignant Hematopoiesis. Cheng J, Guo S (co-first and co-corresponding author), Chen S, Mastriano SJ, Liu C, D'Alessio AC, Hysolli E, Guo Y, Yao H, Megyola CM, Li D, Liu J, Pan W, Roden CA, Zhou XL, Heydari K, Chen J, Park IH, Ding Y, Zhang Y, Lu J. Cell Rep. 2013 Oct 31;5(2):471-81.
Dynamic migration and cell-cell interactions of early reprogramming revealed by high-resolution time-lapse imaging.
Dynamic migration and cell-cell interactions of early reprogramming revealed by high-resolution time-lapse imaging. Megyola CM, Gao Y, Teixeira AM, Cheng J, Heydari K, Cheng EC, Nottoli T, Krause DS, Lu J, Guo S. Stem Cells. 2013 May;31(5):895-905.
Complex oncogene dependence in microRNA-125a-induced myeloproliferative neoplasms.
Complex oncogene dependence in microRNA-125a-induced myeloproliferative neoplasms. Guo S, Bai H, Megyola CM, Halene S, Krause DS, Scadden DT, Lu J. Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16636-41.
A microRNA regulating adult hematopoietic stem cells.
A microRNA regulating adult hematopoietic stem cells. Guo S, Scadden DT. Cell Cycle. 2010 Sep 15;9(18):3637-8.
MicroRNA miR-125a controls hematopoietic stem cell number.
MicroRNA miR-125a controls hematopoietic stem cell number. Guo S, Lu J, Schlanger R, Zhang H, Wang JY, Fox MC, Purton LE, Fleming HH, Cobb B, Merkenschlager M, Golub TR, Scadden DT. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14229-34.
Compartmentalized organization: a common and required feature of stem cell niches?
Compartmentalized organization: a common and required feature of stem cell niches? Greco V, Guo S. Development. 2010 May;137(10):1586-94.
Liu J, Guo B, Chen Z, Wang N, Iacovino M, Cheng J, Roden C, Pan W, Khan S, Chen S, Kyba M, Fan R, Guo S, Lu J: miR-125b promotes MLL-AF9-driven murine acute myeloid leukemia involving a VEGFA-mediated non-cell-intrinsic mechanism. Blood. 2017 Mar 16; 2017 Jan 4. PMID: 28053194
Cheng J, Roden CA, Pan W, Zhu S, Baccei A, Pan X, Jiang T, Kluger Y, Weissman SM, Guo S, Flavell RA, Ding Y, Lu J: A Molecular Chipper technology for CRISPR sgRNA library generation and functional mapping of noncoding regions. Nat Commun. 2016 Mar 30; 2016 Mar 30. PMID: 27025950
Guo S, Zi X, Schulz VP, Cheng J, Zhong M, Koochaki SH, Megyola CM, Pan X, Heydari K, Weissman SM, Gallagher PG, Krause DS, Fan R, Lu J: Nonstochastic reprogramming from a privileged somatic cell state. Cell. 2014 Feb 13; 2014 Jan 30. PMID: 24486105
Cheng J, Guo S, Chen S, Mastriano SJ, Liu C, D'Alessio AC, Hysolli E, Guo Y, Yao H, Megyola CM, Li D, Liu J, Pan W, Roden CA, Zhou XL, Heydari K, Chen J, Park IH, Ding Y, Zhang Y, Lu J: An extensive network of TET2-targeting MicroRNAs regulates malignant hematopoiesis. Cell Rep. 2013 Oct 31; 2013 Oct 10. PMID: 24120864
Nolde MJ, Cheng EC, Guo S, Lin H: Piwi genes are dispensable for normal hematopoiesis in mice. PLoS One. 2013; 2013 Aug 23. PMID: 24058407
Megyola CM, Gao Y, Teixeira AM, Cheng J, Heydari K, Cheng EC, Nottoli T, Krause DS, Lu J, Guo S: Dynamic migration and cell-cell interactions of early reprogramming revealed by high-resolution time-lapse imaging. Stem Cells. 2013 May. PMID: 23335078
Adams BD, Guo S, Bai H, Guo Y, Megyola CM, Cheng J, Heydari K, Xiao C, Reddy EP, Lu J: An in vivo functional screen uncovers miR-150-mediated regulation of hematopoietic injury response. Cell Rep. 2012 Oct 25; 2012 Oct 19. PMID: 23084747
Guo S, Bai H, Megyola CM, Halene S, Krause DS, Scadden DT, Lu J: Complex oncogene dependence in microRNA-125a-induced myeloproliferative neoplasms. Proc Natl Acad Sci U S A. 2012 Oct 9; 2012 Sep 24. PMID: 23012470
Guo S, Scadden DT: A microRNA regulating adult hematopoietic stem cells. Cell Cycle. 2010 Sep 15; 2010 Sep 28. PMID: 20855952
Greco V, Guo S: Compartmentalized organization: a common and required feature of stem cell niches? Development. 2010 May. PMID: 20430743