个人简介
PhD Yale University (1987)
MD Yale University (1987)
Resident Yale-New Haven Hospital
Fellow Yale-New Haven Hospital
Board Certification AB of Radiology, Radiation Oncology (1992)
研究领域
DNA Repair; Genetics; Radiation; Mutagenesis; Gene Targeting; Radiation Oncology; Recombinational DNA Repair
近期论文
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microRNAs in Cancer Cell Response to Ionizing Radiation
Czochor JR and Glazer PM: microRNAs in Cancer Cell Response to Ionizing Radiation. Antioxid Redox Signal. 2013 Nov. 10
Radiation sensitivity and sensitization in melanoma.
Shahbazian D, Bindra RS, Kluger HM, Glazer PM. (2013) Radiation sensitivity and sensitization in melanoma.Pigment Cell Melanoma Res. 2013 Jul 22.
Targeting cancer with a lupus autoantibody.
Hansen JE, Chan G, Liu Y, Hegan DC, Dalal S, Dray E, Kwon Y, Xu Y, Xu X, Peterson-Roth E, Geiger E, Liu Y, Gera J, Sweasy JB, Sung P, Rockwell S, Nishimura RN, Weisbart RH and Glazer PM: Targeting cancer with a lupus autoantibody. Sci Transl Med. 2012 Oct 24;4 (157) :157ra142. PMID: 23100628
Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo.
McNeer NA, Schleifman EB, Cuthbert A, Brehm M, Jackson A, Cheng C, Anandalingam K, Kumar P, Shultz LD, Greiner DL, Mark Saltzman W and Glazer PM: Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo. Gene Ther. 2012 Oct 18; Epub 2012 Oct 18. PMID: 23076379
Hypoxia-induced epigenetic regulation and silencing of the BRCA1 promoter.
Lu Y, Chu A, Turker MS and Glazer PM: Hypoxia-induced epigenetic regulation and silencing of the BRCA1 promoter. Mol Cell Biol. 2011 Aug;31 (16) :3339-50. Epub 2011 Jun 13. PMID: 21670155
MicroRNA regulation of DNA repair gene expression in hypoxic stress.
Crosby ME, Kulshreshtha R, Ivan M, Glazer PM. MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res. 2009 Feb 169(3):1221-9. Epub 2009 Jan 13. Erratum in: Cancer Res. 2009 Apr 169(7):3240.
Repair of DNA lesions associated with triplex-forming oligonucleotides.
Chin JY, Glazer PM. Repair of DNA lesions associated with triplex-forming oligonucleotides. Mol Carcinog. 2009 Apr48(4):389-99. Review.
Repression of RAD51 gene expression by E2F4/p130 in hypoxia.
Bindra, R.S. and Glazer, P.M. (2007). Repression of RAD51 gene expression by E2F4/p130 in hypoxia. Oncogene 26:2048-57.
Specific mutations induced by triplex-forming oligonucleotides in mice.
Vasquez, K.M., Narayanan, L., and Glazer, P.M. (2000). Specific mutations induced by triplex-forming oligonucleotides in mice. Science 290:530-3.