Bennett, Anton M - Yale University - Biological & Biomedical Sciences

个人简介

PhD New York Medical College (1993) Postdoc Cold Spring Harbor Laboratories Postdoc Harvard Medical School

近期论文

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Low-dose dasatinib rescues cardiac function in Noonan syndrome Yi, JS, Huang Y, Kwaczala A.T., Kuo, I.Y., Ehrlich, B.E., Campbell, S.G., Giordano, F.J., Bennett, A.M. (2016) JCI Insight, 1(20):e90220. Mining the function of protein tyrosine phosphatases in health and disease Lee, H., Yi, JS, Lawan, A., Min, K., Bennett AM. (2015) Semin Cell Dev Biol., 37:66-72 Improved Regenerative Myogenesis and Muscular Dystrophy in Mice lacking MKP-5 Shi, H., Verma, M., Zhang, L. Dong, C., Flavell, R.A., and Bennett, A. M. (2013), Improved Regenerative Myogenesis and Muscular Dystrophy in Mice lacking MKP-5, J. Clin. Invest., 123: 2064-2077. Loss of MAP Kinase Phosphatase-1 protects from hepatic steatosis by repression of CIDEC/Fat-specific protein 27 Roth Flach, R.J., Zhang, and Bennett, A.M. (2011) Loss of MAP Kinase Phosphatase-1 protects from hepatic steatosis by repression of CIDEC/Fat-specific protein 27, J. Biol. Chem., 286: 22195-22202. MAPK phosphatase-1 facilitates the loss of oxidative myofibers associated with obesity in mice Roth, R.J., Le, A., Zhang, L., Samuel, V.T., Shulman, J., and Bennett, A.M., (2009) MAPK phosphatase-1 facilitates the loss of oxidative myofibers associated with obesity in mice. J. Clin. Invest., 119:3817-29. Lee H, Min K, Yi JS, Shi H, Chang W, Jackson L, Bennett AM: A Phosphoproteomic Screen Identifies a Guanine Nucleotide Exchange Factor for Rab3A Protein as a Mitogen-activated Protein (MAP) Kinase Phosphatase-5-regulated MAP Kinase Target in Interleukin 6 (IL-6) Secretion and Myogenesis. J Biol Chem. 2017 Mar 3; 2017 Jan 17. PMID: 28096466 Tzouvelekis A, Yu G, Lino Cardenas CL, Herazo-Maya JD, Wang R, Woolard T, Zhang Y, Sakamoto K, Lee H, Yi JS, DeIuliis G, Xylourgidis N, Ahangari F, Lee PJ, Aidinis V, Herzog EL, Homer R, Bennett AM, Kaminski N: SH2 Domain-Containing Phosphatase-2 Is a Novel Antifibrotic Regulator in Pulmonary Fibrosis. Am J Respir Crit Care Med. 2017 Feb 15. PMID: 27736153 Yi JS, Huang Y, Kwaczala AT, Kuo IY, Ehrlich BE, Campbell SG, Giordano FJ, Bennett AM: Low-dose dasatinib rescues cardiac function in Noonan syndrome. JCI Insight. 2016 Dec 8; 2016 Dec 8. PMID: 27942593 Shi H, Gatzke F, Molle JM, Lee HB, Helm ET, Oldham JJ, Zhang L, Gerrard DE, Bennett AM: Mice lacking MKP-1 and MKP-5 Reveal Hierarchical Regulation of Regenerative Myogenesis. J Stem Cell Regen Biol. 2015 Nov 12. PMID: 27064463 Lee H, Bennett AM: Identification of receptor protein tyrosine phosphatases (RPTPs) as regulators of receptor tyrosine kinases (RTKs) using an RPTP siRNA-RTK substrate screen. Methods Mol Biol. 2015. PMID: 25319894 Lawan A, Zhang L, Gatzke F, Min K, Jurczak MJ, Al-Mutairi M, Richter P, Camporez JP, Couvillon A, Pesta D, Roth Flach RJ, Shulman GI, Bennett AM: Hepatic mitogen-activated protein kinase phosphatase 1 selectively regulates glucose metabolism and energy homeostasis. Mol Cell Biol. 2015 Jan; 2014 Oct 13. PMID: 25312648 Lee H, Yi JS, Lawan A, Min K, Bennett AM: Mining the function of protein tyrosine phosphatases in health and disease. Semin Cell Dev Biol. 2015 Jan; 2014 Sep 26. PMID: 25263013 Feriod CN, Nguyen L, Jurczak MJ, Kruglov EA, Nathanson MH, Shulman GI, Bennett AM, Ehrlich BE: Inositol 1,4,5-trisphosphate receptor type II (InsP3R-II) is reduced in obese mice, but metabolic homeostasis is preserved in mice lacking InsP3R-II. Am J Physiol Endocrinol Metab. 2014 Dec 1; 2014 Oct 14. PMID: 25315698 Paardekooper Overman J, Yi JS, Bonetti M, Soulsby M, Preisinger C, Stokes MP, Hui L, Silva JC, Overvoorde J, Giansanti P, Heck AJ, Kontaridis MI, den Hertog J, Bennett AM: PZR coordinates Shp2 Noonan and LEOPARD syndrome signaling in zebrafish and mice. Mol Cell Biol. 2014 Aug; 2014 May 27. PMID: 24865967 Kallen AN, Zhou XB, Xu J, Qiao C, Ma J, Yan L, Lu L, Liu C, Yi JS, Zhang H, Min W, Bennett AM, Gregory RI, Ding Y, Huang Y: The imprinted H19 lncRNA antagonizes let-7 microRNAs. Mol Cell. 2013 Oct 10; 2013 Sep 19. PMID: 24055342 Shi H, Verma M, Zhang L, Dong C, Flavell RA, Bennett AM: Improved regenerative myogenesis and muscular dystrophy in mice lacking Mkp5. J Clin Invest. 2013 May; 2013 Apr 1. PMID: 23543058 Lee H, Bennett AM: Receptor protein tyrosine phosphatase-receptor tyrosine kinase substrate screen identifies EphA2 as a target for LAR in cell migration. Mol Cell Biol. 2013 Apr; 2013 Jan 28. PMID: 23358419 Lawan A, Shi H, Gatzke F, Bennett AM: Diversity and specificity of the mitogen-activated protein kinase phosphatase-1 functions. Cell Mol Life Sci. 2013 Jan; 2012 Jun 14. PMID: 22695679 Mercan F, Lee H, Kolli S, Bennett AM: Novel role for SHP-2 in nutrient-responsive control of S6 kinase 1 signaling. Mol Cell Biol. 2013 Jan; 2012 Nov 5. PMID: 23129808 Ruan HB, Han X, Li MD, Singh JP, Qian K, Azarhoush S, Zhao L, Bennett AM, Samuel VT, Wu J, Yates JR 3rd, Yang X: O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability. Cell Metab. 2012 Aug 8. PMID: 22883232