Baserga, Susan J - Yale University - Biological & Biomedical Sciences

个人简介

PhD Yale University (1988) MD Yale University (1988) Postdoctoral Fellow Yale University

研究领域

Biogenesis; Genetics; Molecular Biology; Ribonucleoproteins; Radiation Oncology; RNA Helicases; Genes, rRNA; Biochemical Processes

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

A protein interaction map of the LSU processome McCann, K.L., Charette, J.M., Vincent, N.G., and Baserga, S.J. A protein interaction map of the LSU processome. Genes Dev. (2015) 29: 862-875. PMC4403261 The molecular basis for ANE syndrome revealed by the large ribosomal subunit processome interactome McCann, K.L., Teramoto, T., Zhang, J., Hall, T.M.T.*, Baserga, S.J.* The molecular basis for ANE syndrome revealed by the large ribosomal subunit processome interactome. eLife (2016) 5:e16381. *co-corresponding authors. PMCID: PMC4859800 Box C/D sRNA stem ends act as stabilizing anchors for box C/D di-sRNPs Yip, W.S.V., Shigematsu, H., Taylor, D.W. and Baserga, S.J. Box C/D sRNA stem ends act as stabilizing anchors for box C/D di-sRNPs. Nucleic Acids Research, in press. Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA Zhang, J., McCann, K.L., Qiu, C., Gonzalez, L.E., Baserga, S.J.*, and Hall, T.M.T.* Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA. Nature Communications, in press. *co-corresponding authors. The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma Tao, T.*, Sondalle, S.B.*, Shi, H.*, Zhu, S., Perez-Atayde, A.R., Peng, J., Baserga, S.J#., and Look, A.T#. The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma. submitted to Oncogene. *These authors contributed equally to this work. #co-corresponding authors. Expression of ribosomopathy genes during Xenopus tropicalis embryogenesis Robson, A., Owens, N.D.L., Baserga, S.J., Khokha, M.K., and Griffin, J.N. Expression of ribosomopathy genes during Xenopus tropicalis embryogenesis. In press, BMC Developmental Biology Determinants of mammalian nucleolar architecture Farley, K.I., Surovtseva, Y., Merkel, J. and Baserga, S.J. Determinants of mammalian nucleolar architecture. (2015) Chromosoma 124: 323-331, PMCID: PMC4534358. Review The contributions of the ribosome biogenesis protein, Utp5/WDR43, to craniofacial development Sondalle, S.B., Baserga, S.J.* and Yelick, P.C.* The contributions of the ribosome biogenesis protein, Utp5/WDR43, to craniofacial development. Journal of Dental Research, in press. *co-corresponding authors. Review Probing the mechanisms underlying human diseases in making ribosomes Farley, K.I. and Baserga, S.J. Probing the mechanisms underlying human diseases in making ribosomes. Biochemical Society Transactions, in press. Review Sondalle SB, Baserga SJ: Ribosomes Need Straight A's to Sleep. Cell. 2017 May 4. PMID: 28475888 Paolini NA, Attwood M, Sondalle SB, Vieira CM, van Adrichem AM, di Summa FM, O'Donohue MF, Gleizes PE, Rachuri S, Briggs JW, Fischer R, Ratcliffe PJ, Wlodarski MW, Houtkooper RH, von Lindern M, Kuijpers TW, Dinman JD, Baserga SJ, Cockman ME, MacInnes AW: A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism. Am J Hum Genet. 2017 Mar 2. PMID: 28257692 Robson A, Owens ND, Baserga SJ, Khokha MK, Griffin JN: Expression of ribosomopathy genes during Xenopus tropicalis embryogenesis. BMC Dev Biol. 2016 Oct 26; 2016 Oct 26. PMID: 27784267 Yip WS, Shigematsu H, Taylor DW, Baserga SJ: Box C/D sRNA stem ends act as stabilizing anchors for box C/D di-sRNPs. Nucleic Acids Res. 2016 Oct 14; 2016 Jun 24. PMID: 27342279 Zhang J, McCann KL, Qiu C, Gonzalez LE, Baserga SJ, Hall TM: Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA. Nat Commun. 2016 Oct 11; 2016 Oct 11. PMID: 27725644 Farley KI, Baserga SJ: Probing the mechanisms underlying human diseases in making ribosomes. Biochem Soc Trans. 2016 Aug 15. PMID: 27528749 McCann KL, Teramoto T, Zhang J, Tanaka Hall TM, Baserga SJ: The molecular basis for ANE syndrome revealed by the large ribosomal subunit processome interactome. Elife. 2016 Apr 14; 2016 Apr 14. PMID: 27077951