Bagriantsev, Slav - Yale University - Biological & Biomedical Sciences

个人简介

PhD University of Illinois at Chicago (2007) Postdoc University of California San Francisco

研究领域

Biochemistry; Biophysics; Ducks; Electrophysiology; Ion Channels; Mechanoreceptors; Neurosciences; Pacinian Corpuscles; Sensory Receptor Cells; Trigeminal Ganglion; Thermoreceptors; Potassium Channels; Anseriformes; Transient Receptor Potential Channels; Voltage-Gated Sodium Channels

近期论文

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Neuronal mechanism for acute mechanosensitivity in tactile-foraging waterfowl. Schneider ER, Mastrotto M, Laursen WJ, Shultz VP, Goodman JB, Funk OH, Gallagher PG, Gracheva EO, Bagriantsev SN. Neuronal mechanism for acute mechanosensitivity in tactile-foraging waterfowl. PNAS 2014, 111(41):14941-6. Tethered protein display identifies a novel Kir3.2 (GIRK2) regulator from protein scaffold libraries. Bagriantsev SN, Chatelain FC, Clark KA, Alagem N, Reuveny E, Minor DL. Tethered protein display identifies a novel Kir3.2 (GIRK2) regulator from protein scaffold libraries. ACS Chem Neurosci 2014, 5(9):812-22. A high-throughput functional screen identifies small molecule regulators of temperature- and mechano sensitive K2P channels. Bagriantsev S, Ang K, Gallardo-Godoy A, Clark K, Arkin M, Renslo A, Minor DL. A high-throughput functional screen identifies small molecule regulators of temperature- and mechano sensitive K2P channels. ACS Chem Biol 2013, 8(8):1841-51. Metabolic and thermal stimuli control K2P2.1 (TREK-1) through modular sensory and gating domains. Bagriantsev S, Clark K, Minor DL. Metabolic and thermal stimuli control K2P2.1 (TREK-1) through modular sensory and gating domains. EMBO J 2012, 31: 3297-3308. Multiple modalities converge on a common gate to control K2P channel function. Bagriantsev S, Peyronnet R, Clark K, Honore E, Minor DL. Multiple modalities converge on a common gate to control K2P channel function. EMBO J 2011, 30: 3594-3606. Variant-specific [PSI+] infection is transmitted by Sup35 polymers within [PSI+] aggregates with heterogeneous protein composition. Bagriantsev S, Gracheva EO, Richmond JE, and Liebman SW. Variant-specific [PSI+] infection is transmitted by Sup35 polymers within [PSI+] aggregates with heterogeneous protein composition. Mol Biol Cell 2008, 19(6):2433-43. Modulation of Aß42 low-n oligomerization using a novel yeast reporter system.17002801 Bagriantsev SN, Liebman SW. Modulation of Aß42 low-n oligomerization using a novel yeast reporter system. BMC Biology 2006, 4(1):32. Specificity of prion assembly in vivo. [PSI+] and [PIN+] form separate structures in yeast. Bagriantsev S, Liebman SW. Specificity of prion assembly in vivo. [PSI+] and [PIN+] form separate structures in yeast. J Biol Chem 2004, 279(49): 51042-8. Laursen WJ, Schneider ER, Merriman DK, Bagriantsev SN, Gracheva EO: Low-cost functional plasticity of TRPV1 supports heat tolerance in squirrels and camels. Proc Natl Acad Sci U S A. 2016 Oct 4; 2016 Sep 16. PMID: 27638213 Schneider ER, Gracheva EO, Bagriantsev SN: Evolutionary Specialization of Tactile Perception in Vertebrates. Physiology (Bethesda). 2016 May. PMID: 27053733 Gracheva EO, Bagriantsev SN: Evolutionary adaptation to thermosensation. Curr Opin Neurobiol. 2015 Oct; 2015 Feb 17. PMID: 25698346 Bagriantsev SN, Gracheva EO: Molecular mechanisms of temperature adaptation. J Physiol. 2015 Aug 15; 2015 Jan 5. PMID: 25433072 Laursen WJ, Anderson EO, Hoffstaetter LJ, Bagriantsev SN, Gracheva EO: Species-specific temperature sensitivity of TRPA1. Temperature (Austin). 2015 Apr-Jun; 2015 Feb 11. PMID: 27227025 Laursen WJ, Mastrotto M, Pesta D, Funk OH, Goodman JB, Merriman DK, Ingolia N, Shulman GI, Bagriantsev SN, Gracheva EO: Neuronal UCP1 expression suggests a mechanism for local thermogenesis during hibernation. Proc Natl Acad Sci U S A. 2015 Feb 3; 2015 Jan 20. PMID: 25605929 Bagriantsev SN, Gracheva EO, Gallagher PG: Piezo proteins: regulators of mechanosensation and other cellular processes. J Biol Chem. 2014 Nov 14; 2014 Oct 10. PMID: 25305018 Schneider ER, Mastrotto M, Laursen WJ, Schulz VP, Goodman JB, Funk OH, Gallagher PG, Gracheva EO, Bagriantsev SN: Neuronal mechanism for acute mechanosensitivity in tactile-foraging waterfowl. Proc Natl Acad Sci U S A. 2014 Oct 14; 2014 Sep 22. PMID: 25246547 Bagriantsev SN, Chatelain FC, Clark KA, Alagem N, Reuveny E, Minor DL Jr: Tethered protein display identifies a novel Kir3.2 (GIRK2) regulator from protein scaffold libraries. ACS Chem Neurosci. 2014 Sep 17; 2014 Jul 16. PMID: 25028803