个人简介
PhD Delhi University (1987)
Postdoctoral Fellow Yale University
Member, Yale Medical School Admissions Committee
研究领域
Acetylcholine; Electrophysiology; Glutamates; Interneurons; Memory; Neurobiology; Nicotine; Psychiatry; Puberty; Signal Transduction; Prefrontal Cortex; Kisspeptins
近期论文
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Melanin-concentrating hormone directly inhibits GnRH neurons and blocks kisspeptin activation: link between energy balance and reproduction
Wu M, Dumalska I, Morozova E, van den Pol A and Alreja M Melanin-concentrating hormone directly inhibits GnRH neurons and blocks kisspeptin activation: link between energy balance and reproduction. PNAS 106(40):17217-22. 2009.
Gonadotropin inhibitory hormone (GnIH) innervates, inhibits basal forebrain vGluT2-GnRH neurons via a direct postsynaptic mechanism
Wu M, Dumalska I, Morozova E, van den Pol A and Alreja M Gonadotropin inhibitory hormone (GnIH) innervates, inhibits basal forebrain vGluT2-GnRH neurons via a direct postsynaptic mechanism. J. Physiology, 587.7:1401-1411, 2009.
The novel tachykinin, hemokinin-1, activates septohippocampal cholinergic neurons via NK1, NK2 and NK3 receptors
Morozova, E. Wu, M., Dumalska, I and Alreja, M. The novel tachykinin, hemokinin-1, activates septohippocampal cholinergic neurons via NK1, NK2 and NK3 receptors. Eur. J. Neurosci., 27(1):114-122, 2008
Excitatory effects of the puberty-initiating peptide kisspeptin and group I metabotropic glutamate receptor agonists differentiate two distinct subpopulations of gonadotropin-releasing hormone neurons
Dumalska I, Wu M, Morozova E, Liu R, van den Pol A, Alreja M (Aug 2008) Excitatory effects of the puberty-initiating peptide kisspeptin and group I metabotropic glutamate receptor agonists differentiate two distinct subpopulations of gonadotropin-releasing hormone neurons., The Journal of neuroscience : the official journal of the Society for Neuroscience, 28(32)8003-13
Neurokinins robustly activate the majority of septohippocampal cholinergic neurons
Morozova E, Wu M, Dumalska I, Alreja M (Jan 2008) Neurokinins robustly activate the majority of septohippocampal cholinergic neurons., The European journal of neuroscience, 27(1)114-22
Muscarine activates the sodium-calcium exchanger via M receptors in basal forebrain neurons
Xu C, Wu M, Morozova E, Alreja M (Oct 2006) Muscarine activates the sodium-calcium exchanger via M receptors in basal forebrain neurons., The European journal of neuroscience, 24(8)2309-13
Histamine Innervation and Activation of Septohippocampal GABAergic Neurones: Involvement of Local ACh Release
Xu C, Michelsen KA, Wu M, Morozova E, Panula P, Alreja M, Histamine Innervation and Activation of Septohippocampal GABAergic Neurones: Involvement of Local ACh Release., The Journal of Physiology, 561(Pt 3):657-70, Dec 2004
Maguire CA, Song YB, Wu M, León S, Carroll RS, Alreja M, Kaiser UB, Navarro VM: Tac1 Signaling is Required for Sexual Maturation and Responsiveness of GnRH Neurons to Kisspeptin in the Male Mouse. Endocrinology. 2017 Apr 21; 2017 Apr 21. PMID: 28444173
Alreja M: Electrophysiology of kisspeptin neurons. Adv Exp Med Biol. 2013. PMID: 23550014
Wu M, Dumalska I, Morozova E, van den Pol A, Alreja M: Melanin-concentrating hormone directly inhibits GnRH neurons and blocks kisspeptin activation, linking energy balance to reproduction. Proc Natl Acad Sci U S A. 2009 Oct 6; 2009 Sep 21. PMID: 19805188
Wu M, Dumalska I, Morozova E, van den Pol AN, Alreja M: Gonadotropin inhibitory hormone inhibits basal forebrain vGluT2-gonadotropin-releasing hormone neurons via a direct postsynaptic mechanism. J Physiol. 2009 Apr 1; 2009 Feb 9. PMID: 19204051
Dumalska I, Wu M, Morozova E, Liu R, van den Pol A, Alreja M: Excitatory effects of the puberty-initiating peptide kisspeptin and group I metabotropic glutamate receptor agonists differentiate two distinct subpopulations of gonadotropin-releasing hormone neurons. J Neurosci. 2008 Aug 6. PMID: 18685025
Morozova E, Wu M, Dumalska I, Alreja M: Neurokinins robustly activate the majority of septohippocampal cholinergic neurons. Eur J Neurosci. 2008 Jan. PMID: 18184316
Xu C, Wu M, Morozova E, Alreja M: Muscarine activates the sodium-calcium exchanger via M receptors in basal forebrain neurons. Eur J Neurosci. 2006 Oct. PMID: 17074051
Xu C, Michelsen KA, Wu M, Morozova E, Panula P, Alreja M: Histamine innervation and activation of septohippocampal GABAergic neurones: involvement of local ACh release. J Physiol. 2004 Dec 15; 2004 Oct 14. PMID: 15486020
Wu M, Hajszan T, Xu C, Leranth C, Alreja M: Group I metabotropic glutamate receptor activation produces a direct excitation of identified septohippocampal cholinergic neurons. J Neurophysiol. 2004 Aug; 2004 Mar 24. PMID: 15044519
Wu M, Zaborszky L, Hajszan T, van den Pol AN, Alreja M: Hypocretin/orexin innervation and excitation of identified septohippocampal cholinergic neurons. J Neurosci. 2004 Apr 7. PMID: 15071100
Xu C, Datta S, Wu M, Alreja M: Hippocampal theta rhythm is reduced by suppression of the H-current in septohippocampal GABAergic neurons. Eur J Neurosci. 2004 Apr. PMID: 15090056