Murugaverl, Balasingam - University of Denver - Department of Chemistry & Biochemistry

个人简介

Ph.D. - ORGANIC CHEMISTRY, University of Denver; Denver, Colorado, May 1989. THESIS: a-Amino Anion Synthetic Equivalents. Developed a BIOMIMETIC synthetic method for the synthesis and elaboration of primary amines by reversible umpolung using imines. M.S. - ORGANIC CHEMISTRY, University of Denver, June 1984. THESIS: Newer Chemistry of the Isomeric Benzoinphenylhydrazones. B.Sc. - Honors Degree in POLYMER CHEMISTRY. Kingston University, Surrey, England, U.K., September 1980. Lecturer/ Director of undergraduate laboratories/ Manager of Mass Spectrometry Facilities. University of Denver. Jan. 97 to present. Research Assistant Professor. Department of Chemistry and Geochemistry, Colorado School of Mines. June 1990 to July 1994 and Sep. 1995 to Dec. 1996. POSTDOCTORAL FELLOW. June 1989 to May 1990. Instructor. Red Rocks Community College, September 1994 to Dec. 1997. Teaching courses in organic, and general chemistry. Research Consultant. School of Pharmacy, University of Colorado. July-Dec. 94

研究领域

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My research interests are very diverse and I prefer working on solutions for current problems. Currently my research focus is on developing chlorine and anti befouling polyamide and polysulfone membranes for water purification and nano-filteration applications. This requires molecular level understanding of the reactions and mechanism that contribute to the deterioration of the macromolecular systems. Unlike biological molecules, characterization of synthetic polymers is extremely difficult due to their inherent physical and chemical properties (solubility, polydispersion, chemical structure of monomer etc.). Therefore, no single analytical technique (like IR, NMR, GPC, CZE, MS, etc.) could completely describe the molecular characteristics of a polymer sample. As a result, part of my current research activity is dedicated to the practice of mass spectrometry in macromolecular characterization, choosing and applying the best instrumentation and experimental approaches. My work on macromolecular characterization has lead me naturally into the field of Bioanalytical chemistry. I have since been involved in undergraduate research projects that involve characterization of biomolecules; like protein profiling, peptide-protein conjugates, DNA adducts and surface modification of proteins to name a few. I also routinely advise my colleagues on their characterization problems. I like utilizing my extensive knowledge of modern mass spectrometry and separation techniques to solve fundamental problems associated with biological molecules like identifying target molecules in complex mixtures that are often present in only trace amounts.