Caprioglio , Helen - University of Southern Colorado

个人简介

B.S., Microbiology, Oregon State University. M.S., Oregon State University. Ph.D., Microbiology, North Carolina State University.

研究领域

My interest is in cellular biology, focusing on how cells function and interact with their environment. This includes several varied projects in cell and microbial biology. A current one is a study of the role of M1-aminopeptidases in cell cycle control in yeast. Aminopeptidase functions or mutations have been linked to several cancers and other disorders in humans. The yeast system provides a student-friendly organism for studying cell cycle regulation. My studies have also included the interaction of CD147 and MCT1 proteins in rat brain endothelial cells. MCT-1 is a transporter whose function may play a crucial role in dealing with stroke or Alzheimer's disease. By using simple systems in the laboratory we can gather information relating to cellular functions in health and disease. My research linked to industry has included testing effectiveness of antimicrobial coatings and polymers generated through nanotechnology. Past work has included studies of small blood vessel remodeling and extracellular matrix composition in response to the hypertensive state in rats, and ethanol tolerance in yeast.

近期论文

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N. Jaksic, E. K. Sinkhorn, M. Druelinger, D. Lehmpuhl, H. Caprioglio, Y. Long, P. Chacon, M. Mincic, J. Mclean, J. Borton, and J. Piquette, Multidisciplinary Cohorts of STEM Scholars: Challenges and Rewards, Proceedings of 2009 ASEE Rocky Mountain Section Annual Conference, Orem, UT, April, 2009. H. Caprioglio and B. Huff, Microbiology Laboratory Manual. Bent Tree Press, 2008. D. Caprioglio and H. Caprioglio, Cell Biology Laboratory Manual. Bent Tree Press, 2008. D. Caprioglio, H. Caprioglio and B. Huff, General Microbiology Laboratory Manual. Bent Tree Press, 2008. R. Chandler, M.M. Diawara, H.M. Walker-Caprioglio, D.E. Williams. 1999. Examination of psoralen-induced photodermatitis in Wistar rats under scanning electron microscopy. J Natural Toxins 8:167-177. R. Rankin and H.Caprioglio. Building Bridges and TriBeta Clubs. 1998. BIOS 69:79-80. H.M. Walker-Caprioglio, D.D. Hunter, P.G. McGuire, S.A. Little and L.J. McGuffee, 1995. Composition in situ and in vitro of vascular smooth muscle laminin in the rat. Cell and Tissue Research 281:187-196. P.G. McGuire, H.M. Walker-Caprioglio, S.A. Little and L.J. McGuffee, 1993. Isolation and culture of rat superior mesenteric artery smooth muscle cells. In Vitro Cell. Devel. Biol. 29A:135-139. H.M. Walker-Caprioglio, J.A. Trotter, S.A. Little and L.J. McGuffee, 1992. Organization of smooth muscle cells and matrix in hypertensive rat arteries. Cell and Tissue Research 269:141-149. H.M. Walker-Caprioglio, T.J. Koob and L.J. McGuffee, 1992. Proteoglycan synthesis in normotensive and spontaneously hypertensive rat arteries in vitro. Matrix 12:308-320. H.M. Walker-Caprioglio, J.A. Trotter, J. Mercure, S.A. Little and L.J. McGuffee, 1991. Organization of rat mesenteric artery after removal of cells or extracellular matrix components. Cell and Tissue Research 264:63-77. H.M. Walker-Caprioglio, W.M. Casey and L.W. Parks, 1990. Yeast membrane sterol modifications in response to growth in the presence of ethanol. Applied and Environmental Microbiology 56:2853-2857. H.M. Walker-Caprioglio, J.M. MacKenzie and L.W. Parks, 1989. Antibodies to nystatin demonstrate polyene sterol specificity and allow immunolabelling of sterols in S. cerevisiae. Antimicrobial Agents and Chemotherapy 33:2092-2095. H.M. Walker-Caprioglio and L.W. Parks, 1987. Autoconditioning factor relieves ethanol-induced growth inhibition of Saccharomyces cerevisiae. Applied and Environmental Microbiology 53:33-35.