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个人简介

Ph.D.:Cell and Molecular Biology, University of Pennsylvania School of Medicine, Philadelphia, PA (2003)

研究领域

We are interested in how stem cells are maintained in an undifferentiated state over the lifetime of the organism, and how the niche influences the choice between staying as a stem cell (“self-renewing”) or undergoing differentiation.

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Shaffer,C, …Leatherman, J, ...Elgin, SA (83 authors)., A Course-Based Research Experience: How Benefits Change with Increased Investment in Instructional Time. CBE Life Sciences, 2014. 13(1): 111-130. Leatherman, J.L. and S. DiNardo, Germline self-renewal requires cyst stem cells, while stat regulates niche adhesion in Drosophila testes. Nature Cell Biology, 2010, 12(8): 806-11. with cover Leatherman, J.L. and S. Dinardo, Zfh-1 controls somatic stem cell self-renewal in the Drosophila testis and nonautonomously influences germline stem cell self-renewal. Cell Stem Cell, 2008, 3(1): 44-54. Leatherman, J.L., L. Levin, J. Boero, and T.A. Jongens, germ cell-less acts to repress transcription during the establishment of the Drosophila germ cell lineage. Current Biology, 2002, 12(19): 1681-5. Leatherman, J.L., K.H. Kaestner, and T.A. Jongens, Identification of a mouse germ cell-less homologue with conserved activity in Drosophila. Mech Dev, 2000, 92(2): 145-53. Kelly, C., A.J. Chin, J.L. Leatherman, D.J. Kozlowski, and E.S. Weinberg, Maternally controlled (beta)-catenin-mediated signaling is required for organizer formation in the zebrafish. Development, 2000, 127(18): 3899-911. Robertson, S.E., T.C. Dockendorff, J.L. Leatherman, D.L. Faulkner, and T.A. Jongens, germ cell-less is required only during the establishment of the germ cell lineage of Drosophila and has activities which are dependent and independent of its localization to the nuclear envelope. Dev Biol, 1999, 215(2): 288-97.

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