Blumenthal, Tom - University of Colorado - Molecular, Cellular, and Developmental Biology

个人简介

Ph.D., John Hopkins University, 1970

研究领域

Current: Regulation of gene expression in aneuploidy. How is gene expression altered due to an extra chromosome 21 in Down Syndrome? Past: Mechanisms of pre-mRNA processing: splicing and 3' end formation; logic of gene organization on C. elegans chromosomes: eukaryotic operons.

近期论文

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A global analysis of C. elegans trans-splicingAllen, MA, Hillier, LW, Waterston, RH, and Blumenthal, T Genome Research, 21(2):255–264. 2011 Identification of transcription start sites of trans-spliced genes: uncovering unusual operon arrangementsMorton, JJ and Blumenthal, T RNA (New York, N.Y.), 17(2):327–337. 2011 Polycistronic pre-mRNA processing in vitro: snRNP and pre-mRNA role reversal in trans-splicingLasda, EL, Allen, MA, and Blumenthal, T Genes & Development, 24(15):1645–1658. 2010 RNA polymerase II C-terminal domain phosphorylation patterns in Caenorhabditis elegans operons, polycistronic gene clusters with only one promoterGarrido-Lecca, A and Blumenthal, T Molecular and Cellular Biology, 30(15):3887–3893. 2010 RNA processing in C. elegansMorton, JJ and Blumenthal, T Methods in Cell Biology, 106:187–217. 2011 Trans-splicingLasda, EL and Blumenthal, T Wiley Interdisciplinary Reviews. RNA, 2(3):417–434. 2011 The Transcription Start Site Landscape of C. elegans.Saito, T.L., Hashimoto, S., Gu, S.G., Morton, J.J., Stadler, M., Blumenthal, T., Fire, A. and Morishita, S., Genome Research. 23(8):134‐1361.