Randolph, Theodore W. - University of Colorado - Chemical and Biological Engineering

个人简介

B.S., University of Colorado (1983) Ph.D. University of California, Berkeley (1987)

近期论文

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Hassett KJ, Meinerz NM, Semmelmann F, Cousins MC, Garcea RL, Randolph TW 2015. Development of a highly thermostable, adjuvanted human papillomavirus vaccine. Eur J Pharm Biopharm 94:220-228. Chisholm CF, Nguyen BH, Soucie KR, Torres RM, Carpenter JF, Randolph TW 2015. In Vivo Analysis of the Potency of Silicone Oil Microdroplets as Immunological Adjuvants in Protein Formulations. J Pharm Sci 104(11):3681-3690. Shomali M, Tanriverdi S, Freitag AJ, Engert J, Winter G, Siedler M, Kaymakcalan Z, Carpenter JF, Randolph TW 2015. Dose Levels in Particulate-Containing Formulations Impact Anti-drug Antibody Responses to Murine Monoclonal Antibody in Mice. Journal of Pharmaceutical Sciences 104(5):1610-1621. Gerhardt, A; Nguyen, BH; Lewus, R; Carpenter, JF; Randolph, TW 2015. Effect of the Siliconization Method on Particle Generation in a Monoclonal Antibody Formulation in Pre-filled Syringes. Journal of Pharmaceutical Sciences Volume: 104 Issue: 5 Pages: 1601-1609 DOI: 10.1002/jps.24387 Mehta SB, Lewus R, Bee JS, Randolph TW, Carpenter JF 2015. Gelation of a Monoclonal Antibody at the Silicone Oil-Water Interface and Subsequent Rupture of the Interfacial Gel Results in Aggregation and Particle Formation. Journal of Pharmaceutical Sciences 104(4):1282-1290. Hassett KJ, Cousins MC, Rabia LA, Chadwick CM, O'Hara JM, Nandi P, Brey RN, Mantis NJ, Carpenter JF, Randolph TW 2013. Stabilization of a recombinant ricin toxin A subunit vaccine through lyophilization. Eur J Pharm Biopharm. 85(2):279-286. Xu Y, Carpenter JF, Cicerone MT, Randolph TW 2013. Contributions of local mobility and degree of retention of native secondary structure to the stability of recombinant human growth hormone (rhGH) in glassy lyophilized formulations. Soft Matter 9(32):7855-7865. Bee, J.S., et al., Production of particles of therapeutic proteins at the air-water interface during compression/dilation cycles. Soft Matter, 2012. 8(40): p. 10329-10335. Britt, K.A., et al., Excipient effects on humanized monoclonal antibody interactions with silicone oil emulsions. Journal of Pharmaceutical Sciences, 2012. 101(12): p. 4419-4432.