朱文博 - 中山大学 - 中山医学院

个人简介

受教育经历： 2005/09-2010/06，中山大学，中山医学院药理系，博士； 2000/09-2005/06，首都医科大学，临床医学系，本科生。研究工作经历： 2013/01-至今，中山大学，中山医学院药理系，副教授； 2010/07-2012/12，中山大学，中山医学院药理系，讲师。

研究领域

研究领域为肿瘤药理，主要研究方向为肿瘤治疗新策略,包括恶性胶质瘤诱导分化治疗和溶瘤病毒疗法。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

(1) Fan Xing, Yizhao Luan, Jing Cai, Sihan Wu, Jialuo Mai, Jiayu Gu, Haipeng Zhang, Kai Li, Yuan Lin, Xiao Xiao, Jiankai Liang, Yuan Li, Wenli Chen, Yaqian Tan,Longxiang Sheng, Bingzheng Lu, Wanjun Lu, Mingshi Gao，Pengxin Qiu, Xingwen Su,Wei Yin, Jun Hu, Zhongping Chen, Ke Sai , Jing Wang, Furong Chen, Yinsheng Chen, Shida Zhu， Dongbing Liu, Shiyuan Cheng, Zhi Xie*, Wenbo Zhu*, Guangmei Yan*. Anti-Warburg Effect Elicited by cAMP-PGC1α Pathway Drives Differentiation of Glioblastoma Cells into Astrocytes. Cell Reports, 2016, accepted. （中科院一区） (2) Wenbo Zhu#, Yanqiu Ou, Yan Li,Ru Xiao, Minfeng Shu, Yuehan Zhou, Jun Xie, Songmin He, Pengxin Qiu,and Guangmei Yan*. A Small-Molecule Triptolide Suppresses Angiogenesis and Invasion of Human Anaplastic Thyroid Carcinoma cells via Down-Regulation of the Nuclear Factor-κB Pathway. Molecular Pharmacology, 2009, 75:1-8.（中科院二区） (3) Wenbo Zhu , Songmin He , Yan Li , Pengxin Qiu, Minfeng Shu, Yanqiu Ou, Yuehan Zhou, Tiandong Leng, Jun Xie, Xiaoke Zheng, Dong Xu, Xingwu Su, Guangmei Yan. Anti-angiogenic activity of triptolide in anaplastic thyroid carcinoma is mediated by targeting vascular endothelial and tumor cells. Vascular Pharmacology, 2010, 52: 46-54. （中科院二区） (4) Songmin He#, Wenbo Zhu#, Yuxi Zhou, Yijun Huang, Yanqiu Ou, Yan Li, Guangmei Yan*. Transcriptional and post-transcriptional downregulation of cyclin D1 contributes to C6 glioma cell differentiation induced by Forskolin. Journal of Cellular Biochemistry, 2011, 112:2241-2249. （中科院二区） (5) Xiaoqiang Sun #*, Xiaoke Zheng#, Jiajun Zhang, Tianshou Zhou, Guangmei Yan, Wenbo Zhu*. Mathematical modeling reveals a critical role for cyclin D1 dynamics in phenotype switching during glioma differentiation. FEBS Letters, 2015, 589: 2304-2311. （中科院三区） (1) Wenbo Zhu and Guangmei Yan (2011). The Molecular Mechanism for Differentiation Therapy of Malignant Glioma, Brain Tumors - Current and Emerging Therapeutic Strategies, Ana L. Abujamra (Ed.), ISBN: 978-953-307-588-4, InTech. (2) Sihan Wu, Wenbo Zhu and Guangmei Yan (2012). Evolvement of microRNAs as therapeutic targets for malignant gliomas- Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications, Terry Lichtor (Ed.), ISBN 980-953-307-523-0, InTech.