向秋玲 - 中山大学 - 中山医学院

个人简介

中山大学干细胞与组织工程研究中心、中山医学院生理学教研室副教授，硕导。1996-2006年就读于中山大学中山医学院，分别获临床医学学士、生理学博士学位。2007年访问香港中文大学。2009年访问美国印第安纳大学。2015-2016年美国耶鲁大学访问学者。

研究领域

主要从事干细胞在心血管疾病、恶性肿瘤等重大疾病中的作用机制及转化研究。

近期论文

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Xiang Q, Liao Y, Chao H, Huang W, Liu J, Chen H, Hong D, Zou Z, Xiang AP, Li W*. ISL1 overexpression enhances the survival of transplanted human mesenchymal stem cells in a murine myocardial infarction model. Stem Cell Res Ther. 2018 Feb 26;9(1):51. Xiang Q, Hong D, Liao Y, Cao Y, Liu M, Pang J, Zhou J, Wang G, Yang R, Wang M*, Xiang AP*. Overexpression of gremlin1 in mesenchymal stem cells improves hindlimb ischemia in mice by enhancing cell survival. J Cell Physiol. 2017 May;232(5):996-1007. Xu J#, Xiang Q#(co-first author), Lin G, Fu X, Zhou K, Jiang P, Zheng S, Wang T*. Estrogen improved metabolic syndrome through down-regulation of VEGF and HIF-1α to inhibit hypoxia of periaortic and intra-abdominal fat in ovariectomized female rats. Mol Biol Rep. 2012 Aug;39(8):8177-85. Xiang Q, Lin G, Xu J, Zheng S, Chen S, Zhou K, Wang T*. The role of caveolin1 and sprouty1 in genistein's regulation of vascular smooth muscle cell and endothelial cell proliferation. Eur J Pharmacol. 2010 Dec 1;648(1-3):153-61. Xiang Q, Lin G, Fu X, Wang S, Wang T*. The role of peroxisome proliferator- activated receptor-gamma and estrogen receptors in genistein-induced regulation of vascular tone in female rat aortas.Pharmacology. 2010;86(2):117-24 Xiang Q, Chen Y, Lin G, Tan Z, Wang T*. Effects of selective estrogen receptor modulator raloxifene plus 17-beta estradiol in aorta and mammary gland of female experimental atherosclerosis rabbits and possible involvement of ERK signal transduction pathway. Chin J Physiol. 2006 Jun 30;49(3):132-40. Wang T*, Xiang Q, Chen J, Pan H, Cui Y. Raloxifene plus 17beta-estradiol inhibits proliferation of primary cultured vascular smooth muscle cells and human mammary endothelial cells via the janus kinase/signal transducer and activator of transcription3 cascade. Eur J Pharmacol. 2007 Apr 30;561(1-3):7-13. Lin G, Xiang Q, Fu X, Wang S, Wang S, Chen S, Shao L, Zhao Y, Wang T*. Heart rate variability biofeedback decreases blood pressure in prehypertensive subjects by improving autonomic function and baroreflex. J Altern Complement Med. 2012 Feb;18(2):143-52. Cui Y, Tan Z, Fu X, Xiang Q, Xu J, Wang T*. 17 beta-estradiol attenuates pressure overload-induced myocardial hypertrophy through regulating caveolin-3 protein in ovariectomized female rats. Mol Biol Rep. 2011 Nov;38(8):4885-92. Tan Z, Zhou L, Li Y, Cui Y, Xiang Q, Lin G, Wang T*. E₂-BSA activates caveolin-1 via PI₃K/ERK1/2 and lysosomal degradation pathway and contributes to EPC proliferation. Int J Cardiol. 2012 Jun 28;158(1):46-53. Chen Y, Cui Y, Lin J, Xiang Q, Liu W, Wang T*. Modulatory role of estradiol in nicotinic antinociception in adult female rats. Life Sci. 2009 Jul 3;85(1-2):91-6. Jiang P, Xu J, Zheng S, Huang J, Xiang Q, Fu X, Wang T*. 17beta-estradiol down-regulates lipopolysaccharide-induced MCP-1 production and cell migration in vascular smooth muscle cells. J Mol Endocrinol. 2010 Aug;45(2):87-97. Zheng S, Huang J, Zhou K, Zhang C, Xiang Q, Tan Z, Wang T*, Fu X*. 17β-Estradiol enhances breast cancer cell motility and invasion via extra-nuclear activation of actin-binding protein ezrin.PLoS One. 2011;6(7):e22439. Zheng S, Huang J, Zhou K, Xiang Q, Zhang Y, Tan Z, Simoncini T, Fu X*, Wang T*. Progesterone enhances vascular endothelial cell migration via activation of focal adhesion kinase. J Cell Mol Med. 2012 Feb;16(2):296-305.