曹开源 - 中山大学 - 中山医学院

个人简介

曹开源，教授，医学博士，中山大学中山医学院免疫学和临床检验诊断学博士导师和硕士导师，中山大学临床检验标准化研究中心主任，中山大学-香港大学（粤港）传染病监测联合实验室执行主任，广东省微生物与免疫学学会副主任委员，广东省检验医学学会委员，广东省免疫学会理事，广东省政府人感染H7N9禽流感病毒防控专家组专家。

研究领域

主要从事肿瘤免疫和病毒免疫及免疫干预与个体化健康管理的研究。成功建立了基因工程抗体及肿瘤基因及免疫治疗研究平台，对病毒和肿瘤的免疫机制和分子诊断等方面进行了深入研究。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1） New Hepatitis E Virus Genotype in Bactrian Camels, Xinjiang, China, 2013. Emerg Infect Dis. 2016 Dec 22(12):2219-2221 2）Clinical epidemiology and molecular proﬁling of human bocavirus in faecal samples from children with diarrhoea in Guangzhou, China Epidemiol. Infect., 2014 Dec 3:1-15 3）Epidemiology characteristics of respiratory viruses found in children and adults with respiratory tract infections in southern China. International Journal of Infectious Diseases,2014,25 159–164. 4）Outbreak of PER-1 and diversity of β-lactamases among ceftazidime-resistant Pseudomonas aeruginosa clinical isolates.J Med Microbiol. 2014 Mar;63(3):386-992 5）OprD mutations and inactivation in imipenem-resistant Pseudomonas aeruginosa isolates from China.Infect Genet Evol. 2014 Jan;21:124-128 6) Surveillance and Genome Analysis of Human Bocavirus in Patients with Respiratory Infection in Guangzhou,China. PLOS ONE,2012,7(9) :e44876 7) A two-year surveillance of 2009 pandemic influenza A (H1N1) in Guangzhou, China: from pandemic to seasonal influenza?PLOS ONE,2011,6(11): e28027 8) A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection. Journal of Viral Hepatitis.2009,16:45-52 9) Detection of serum neopterin for early assessment of dengue virus infection.Journal of Infection,2006,Sep;53(3):152-8 10) Amino acid sequence analysis and identiﬁcation of mutations under positive selection in hemagglutinin of 2009 inﬂuenza A (H1N1) isolates. Virus Genes,2010,41(3):3329-340 11) 广州地区新型H1N1流感病毒PB1-F2基因进化和变异分析.病毒学报，2012,28(4):317-323 12） Bax-interacting factor-1 inhibits cell proliferation and promotes apoptosis in prostate cancer cells. Oncol Rep. 2016，36：3513-3521 13）Screening and identification of significant genes related to tumor metastasis and PSMA in prostate cancer using microarray analysis. Oncol Rep. 2013，30：1920-1928 14) New alternatively spliced variant of prostate-specific membrane antigen PSM-E suppresses the proliferation, migration and invasiveness of prostate cancer cells. International Journal of Oncology ,2012,40(6):1977-1985 15) High Expression of PSM-E Correlated With Tumor Grade in Prostate Cancer:A New Alternatively Spliced Variant of Prostate-Specific Membrane Antigen The Prostate,2007,67:1791-1800 16) The expression and role of protein kinase C (PKC) epsilon in clear cell renal cell carcinoma. Journal of Experimental & Clinical Cancer Research, 2011, 30:88-97. 17) The Antitumor Activity of Homoharringtonine against Human Mast Cells Harboring the KIT D816V Mutation. Molecular Cancer Therapeutics,2010, 9(1):211-223 18) Predominant immature CD8alpha+ dendritic cells prevent graft-versus-host disease but do not increase the risk of leukemia recurrence. European Journal of Haematology,2007,78(3):235-245 19) Complementary activation of peripheral natural killer cell immunity in nasopharyngeal carcinoma. Cancer Sci,2006,Sep;97(9):912-9