赵蔚 - 中山大学 - 中山医学院

个人简介

赵蔚，教授。2004年和2009年于南京大学获生物学士和博士学位。2009年8月至2015年3月分别在美国Baylor College of Medicine从事博士后研究和康奈尔大学Weill医学院附属Methodist医院从事助理研究员工作。

研究领域

从事干细胞与癌症表观遗传学和表观遗传分子药理学的研究工作，在干细胞和肿瘤表观遗传调控与分子药理学等领域取得重要成果。

近期论文

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Chensong Huang (#); Junjun Chu(#) ; Xiaoxu Zhu; Jianhui Li; Xitai Huang; Jianpeng Cai; Wei Zhao(*) ; Xiaoyu Yin (*). The C/EBPβ-LINC01133 axis promotes cell proliferation in pancreatic ductal adenocarcinoma through upregulation of CCNG1, Cancer Lett., 2018.2.16, S0304-3835(18): 30153~30158 Wei Zhao(#) ; Peng Tan(#) ; Qingyuan Zhu(#) ; Adebusola Ajibade; Teng Long; Wenyong Long; Qingtian Li; Pinghua Liu; Bo Ning; Helen Y Wang; Rongfu Wang (*) Tgfbr2 inactivation facilitates cellular plasticity and development of Pten-null prostate cancer, J Mol Cell Biol., 2017.12.8, Epub ahead of print Jingxin Mo(#) ; Li Wang(#) ; Xiaojia Huang; Bing Lu; Changye Zou; Lili Wei; Junjun Chu; Paul K. Eggers; Shen Chen; Colin L. Raston; Jun Wu(*) ; Lee Yong Lim(*); Wei Zhao (*). Multifunctional nanoparticles for co-delivery of paclitaxel and carboplatin against ovarian cancer by inactivating the JMJD3-HER2 axis, Nanoscale, 2017.9.14, 9(35): 13142~13152 Lili Wei(#) ; Yunfang Yang(#) ; Kun Shi; Jun Wu; ; Wei Zhao(*), Jingxin Mo(*). Preparation and Characterization of Loperamide-Loaded Dynasan 114 Solid Lipid Nanoparticles for Increased Oral Absorption In the Treatment of Diarrhea, Front Pharmacol, 2016.09.21, 7 Wei Zhao(#) ; Qingtian Li; Stephen Ayers; Yifeng Gu; Zhong Shi; Qingyuan Zhu; Yidong Chen; Helen Wang; Rongfu Wang(*) , Jmjd3 Inhibits Reprogramming by Upregulating Expression of INK4a/ Arf and Targeting PHF20 for Ubiquitination, Cell, 2013.2.28, 152(5): 1037~1050 Qingyuan Zhu(#) ; Peng Tan(#) ; Yinyin Li; Meng Lin; Chaoran Li; Jingrong Mao; Jun Cui; Wei Zhao; Helen Y Wang; Rongfu Wang(*). DHX29 functions as a RNA co-sensor for MDA5-mediated EMCV-specific antiviral immunity, PLoS Pathog, 2018.2.20, 14(2) Wenyong Long(#); Wei Zhao (#); Bo Ning; Jing Huang; Junjun Chu; Linfeng Li; Qianquan Ma; Changsheng Xing; Helen Y Wang; Qing Liu; Rongfu Wang (*). PHF20 collaborates with PARP1 to promote stemness and aggressiveness of neuroblastoma cells through activation of SOX2 and OCT4., J Mol Cell Biol., 2018.2.14, Epub ahead of print Chenglei Wu; Zexiong Su; Meng Lin; Jiayu Ou; Wei Zhao; Jun Cui(*) ; Rongfu Wang (*), NLRP11 attenuates Toll-like receptor signalling by targeting TRAF6 for degradation via the ubiquitin ligase RNF19A, Nat Commun., 2017.12.7, 8(1). Chunliu Huang; Junjie Shi; Yibin Guo; Weijun Huang; Shanshan Huang; Siqi Ming; Xingui Wu; Rui Zhang; Junjun Ding; Wei Zhao; Jie Jia; Xi Huang; Andy Peng Xiang; Yongsheng Shi; Chengguo Yao (*), A snoRNA modulates mRNA 3' end processing and regulates the expression of a subset of mRNAs., Nucleic Acids Res., 2017.9.6, 45(15): 8647~8660 Bo Ning; Wei Zhao; Chen Qian; Pinghua Liu; Qingtian Li; Wenyuan Li; Rongfu Wang (*), USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components, Nat Commun, 2017.8.24, 8 (1) Wenyong Long(#) ; Yang Yi(#) ; Shen Chen; Qi Cao; Wei Zhao (*); Qing Liu (*). Potential New Therapies for Pediatric Diffuse Intrinsic Pontine Glioma, Front Pharmacol., 2017.7.25, 8(495) Fangkun Liu (#); Jing Huang(#); Bo Ning; Zhixiong Liu; Shen Chen(*) ; Wei Zhao(*). Drug Discovery via Human-Derived Stem Cell Organoids Front Pharmacol 2016.09.22, 7 Chenglei Wu; Yexin Yang; Jiayu Ou; Liang Zhu; Wei Zhao; Jun Cui(*). LRRC14 attenuates Toll-like receptor-mediated NF-kappaB signaling through disruption of IKK complex. , Exp Cell Res, 2016.9.10, 347(1): 65~73 Bing Lu; Xiaojia Huang; Jingxin Mo (*); Wei Zhao (*). Drug Delivery Using Nanoparticles for Cancer Stem-Like Cell Targeting, Frontiers in Pharmacology, 2016.04.12, 7. Bo Ning; Wenyuan Li; Wei Zhao; Rongfu Wang (*). Targeting epigenetic regulations in cancer. , Acta Biochim Biophys Sin (Shanghai), 2016.1, 48(1): 97~109 Qingtian Li; Jia Zou; Mingjun Wang; Xilai Ding; Iouri Chepelev; Xikun Zhou; Wei Zhao; Gang Wei; Jun Cui; Keji Zhao; Helen Y Wang; Rong-Fu Wang (*). Critical role of histone demethylase Jmjd3 in the regulation of CD4+ T-cell differentiation. , Nat Commun, 2014.12.22, 5: 5780~5780 Mingjun Wang; Bingnan Yin; Satoko Matsueda; Lijuan Deng; Ying Li; Wei Zhao; Jia Zou; Qingtian Li; Christopher Loo; Rong-Fu Wang; Helen Y Wang (*). Identification of special AT-rich sequence binding protein 1 as a novel tumorantigen recognized by CD8+ T cells: implication for cancer immunotherapy. PLoS One, 2013, 8(2): e56730~e56730