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个人简介

2002年获微生物学博士学位;2002-2004年,于美国弗吉尼亚州立大学(VCU)接受博士后培训;2005-2008年,在美国加利福尼亚大学(UCSB)任研究助理。

研究领域

研究方向是宿主细胞与登革病毒之间的相互作用,及细胞抗病毒感染的固有免疫应答调控机制。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Xiaoyan Chen, Jun Xia, Qirui Zhao, Yi Wang, Jingyu Liu, Lianqiang Feng, Junfang He*, Ping Zhang*. Eukaryotic initiation factor 4AI interacts with NS4A of Dengue virus and plays an antiviral role. Biochemical and Biophysical Research Communications, 2015, 461 (2015): 148-153 2. Yuye Li, Siyu Wu, Jieying Pu, Xi Huang, Ping Zhang*. Dengue Virus Upregulates Expression of Notch Ligands Dll1 and Dll4 Through IFN-β Signaling Pathway. Immunology, 2015, 144(1):127-38 3. Peifen Zhang#, Yuye Li#, Jun Xia, Junfang He, Jieying Pu, Jiong Xie, Siyu Wu, Lianqiang Feng, Xi Huang, Ping Zhang*. IPS-1 plays an essential role in dsRNA-induced stress granule formation by interacting with PKR and promoting its activation. Journal of Cell Science, 2014, 127: 2471-2482 4. Siyu Wu, Li He, Yuye Li, Tinglong Wang, Lianqiang Feng, Lifang Jiang, Ping Zhang*, Xi Huang*. miR-146a facilitates replication of dengue virus by dampening interferon induction by targeting TRAF6. Journal of Infection. 2013, 67, ( 4): 329–341 5. Yuye Li, Jiong Xie, Siyu Wu, Jun Xia, Peifen Zhang, Chao Liu, Ping Zhang*, Xi Huang*. Protein Kinase Regulated by dsRNA Downregulates the Interferon Production in Dengue Virus- and dsRNA-stimulated Human Lung Epithelial Cells. PLoS One. 2013, 8(1):e55108 6. Ping Zhang,Siyu Wu, Lietao Li, Zhaoduan Liang , Yuye Li, Lianqiang Feng, Xi Huang*. Adjuvant PIKA protects hepatoma cells from dengue virus infection by promoting TBK-1 dependent innate immune response. Archives of Virology, 2013, 158(4):829-38 7. Zhaoduan Liang, Siyu Wu, Yuye Li, Li He, Minhao Wu, Lifang Jiang, Lianqiang Feng, Ping Zhang*, Xi Huang*. Activation of Toll-Like Receptor 3 Impairs the Dengue Virus Serotype 2 Replication through Induction of IFN-b in Cultured Hepatoma Cells. PLoS One. 2011, 6(8):e23346 8. Minhao Wu, Anping Peng, Mingxia Sun, Qiuchan Deng, Linda D. Hazlett, Jin Yuan, Xialin Liu, Qianying Gao, Lianqiang Feng, Junfang He, Ping Zhang*, Xi Huang*. TREM-1 Amplifies Corneal Inflammation after Pseudomonas aeruginosa Infection by Modulating Toll-Like Receptor Signaling and Th1/Th2-Type Immune Responses. Infection and Immunity. 2011, 79(7):2709-16. 9. Ping Zhang, Jeffrey Langland, Bertram Jacobs, Charles Samuel*. Protein Kinase PKR-Dependent Activation of Mitogen-Activated Protein Kinases Occurs through Mitochondrial Adapter IPS-1 and Is Antagonized by Vaccinia Virus E3L. Journal of Virology, 2009, 83: 5718-5725. 10. Ping Zhang, Charles Samuel*. Induction of protein kinase PKR-dependent activation of interferon regulatory factor 3 by vaccinia virus occurs through adapter IPS-1 signaling. Journal of Biological Chemistry, 2008, 283: 34580-34587. 11. Ping Zhang, Bertram Jacobs,Charles Samuel*. Loss of protein kinase PKR expression in human cells complements the vaccinia virus E3L deletion mutant phenotype by restoration of viral protein synthesis. Journal of Virology, 2008, 82: 840-848. 12. Ping Zhang, Charles Samuel*. Protein Kinase PKR Plays a Stimulus- and Virus-dependent Role in Apoptotic Death and Virus Multiplication in Human Cells. Journal of Virology, 2007, 81: 8192-8200. 13. Christopher McAllister, Ann Toth, Ping Zhang, Patricia Devaux, Roberto Cattaneo, Charles E. Samuel*. Mechanisms of Protein Kinase PKR-Mediated Amplification of Beta Interferon Induction by C Protein-Deficient Measles Virus. Journal of Virology, 2010, 84(1):380-386.

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