颜光美 - 中山大学 - 中山医学院

个人简介

颜光美，现任中山大学副校长，中山大学药理学教授, 博士生导师。颜教授于1987年任职于中山大学药理教研室，1991年赴美国国立卫生研究所精神卫生研究所(NIMH/NIH)作访问科学家，1994年后先后在美国礼来公司中枢神经系统研究所和美国印第安那大学药理和毒理系做访问科学家，1996年回国享受国务院特殊津贴，并获“国家杰出青年科学基金”资助。现任教育部科学技术委员会学部委员，中山大学中山医学院药理学国家重点学科学术带头人之一，药理国家级精品课程带头人，神经科学研究中心主任，《中国药理学与毒理学杂志》编委和教育部规划教材《药理学》主编，美国药典顾问。

研究领域

恶性肿瘤治疗新策略溶瘤病毒疗法和诱导分化疗法”和“缺血缺氧性脑损伤的分子遗传学机制研究”。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1 Guangmei Yan*, Guojie Zhang, Xiaodong Fang, Yanfeng Zhang, Cai Li, Fei Ling, David N Cooper, Qiye Li, Yan Li, Alain J van Gool, Hongli Du, Jiesi Chen, Ronghua Chen, Pei Zhang, Zhiyong Huang, John R Thompson, Yuhuan Meng, Yinqi Bai, Jufang Wang, Min Zhuo, Tao Wang, Ying Huang, Liqiong Wei, Jianwen Li, Zhiwen Wang, Haofu Hu, Pengcheng Yang, Liang Le, Peter D Stenson, Bo Li, Xiaoming Liu, Edward V Ball, Na An, Quanfei Huang, Yong Zhang, Wei Fan, Xiuqing Zhang, Yingrui Li, Wen Wang, Michael G Katze, Bing Su, Rasmus Nielsen, Huanming Yang, Jun Wang, Xiaoning Wang & Jian Wang. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Nature Biotechnology, 2011, 29: 1019-1025. (IF = 39.08) 2 Yuan Lin#, Haipeng Zhang#, Jiankai Liang#, Kai Li, Wenbo Zhu, Liwu Fu, Fang Wang, Xiaoke Zheng, Huijuan Shi, Sihan Wu, Xiao Xiao, Lijun Chen, Lipeng Tang, Min Yan, Xiaoxiao Yang, Yaqian Tan, Pengxin Qiu, Yijun Huang, Wei Yin, Xinwen Su, Haiyan Hu, Jun Hu*, and Guangmei Yan*. Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers.PNAS, 2014,111(42):4504-4512.. (IF: 9.809) 3 Yan Li, Wei Yin, Xia Wang, Wenbo Zhu, Yijun Huang and Guangmei Yan*: Cholera toxin induces malignant glioma cell differentiation via the PKA/CREB pathway. PNAS, 2007, 104: 13438-43. (IF: 9.809) 4 Sihan Wu, Yuan Lin, Dong Xu, Jiesi Chen, Minfeng Shu, Yuehan Zhou, Wenbo Zhu, Xingwen Su, Yuxi Zhou, Pengxin Qiu and Guangmei Yan*. MiR-135a Functions as a Selective Killer of Malignant Glioma. Oncogene, 2012, 31: 3866-3874. (IF = 8.559) 5 Haiyan Hu, Yuehan Zhou, Tiandong Leng, Ailing Liu, Youqiong Wang, Xiuhua You, Jingkao Chen, Lipeng Tang, Wenli Chen, Pengxin Qiu, Wei Yin, Yijun Huang, Jingxia Zhang, Liwei Wang, Hanfei Sang and Guangmei Yan*. A major cholesterol metabol i te cholestane-3β, 5α, 6β-triolfunctions as an endogenous neuroprotectant. The Journal of Neuroscience, August 20, 2014, 34(34): 11426 –11438. (IF: 6.747) 6 Kai Li#, Haipeng Zhang#, Jianguang Qiu, Yuan Lin, Jiankai Liang, Xiao Xiao,Liwu Fu, Fang Wang, Jing Cai, Yaqian Tan, Wenbo Zhu, Wei Yin, Bingzheng Lu, Fan Xing, Lipeng Tang, Min Yan, Jialuo Mai, Yuan Li, Wenli Chen, Pengxin Qiu, Xingwen Su, Guangping Gao, Phillip W L Tai, Jun Hu* and Guangmei Yan*. Activation of cyclic adenosine monophosphate pathway increases the sensitivity of cancer cells to the oncolytic virus M1. Molecular Therapy, 2016, 24(1): 156–165. (IF =6.227) 1.Wenbo Zhu and Guangmei Yan (2011). The Molecular Mechanism for Differentiation Therapy of Malignant Glioma, Brain Tumors - Current and Emerging Therapeutic Strategies, Ana L. Abujamra (Ed.), ISBN: 978-953-307-588-4, InTech. Available from: http://www.intechopen.com /articles /show /title /the-molecular-mechanism-for-differentiation-therapy-of-malignant-glioma. 2.Sihan Wu, Wenbo Zhu and Guangmei Yan (2012). Evolvement of microRNAs as therapeutic targets for malignant gliomas, Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications. Terry Lichtor. (Ed.),ISBN 980-953-307-523-0, InTech.