李春凌 - 中山大学 - 中山医学院

个人简介

1999年初以访问学者身份赴丹麦奥胡斯大学，从事肾脏病理生理学研究，2001年至2004年在奥胡斯大学水盐研究中心及skyjby医院临床研究所攻读医学博士学位，并于2004年获得肾脏病理生理医学博士学位。2004年9月以博士后身份赴美国科罗拉多州大学医学院高血压与肾脏疾病科继续从事肾脏的生理和病理生理学研究。2006年晋职研究型讲师

研究领域

从事肾脏生理学和病理生理学

近期论文

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1. Wang W, Li C, Yang T*, Protection of Nitro-Fatty Acid against Kidney Diseases. Am J Physiol Renal Physiol. 2015 Dec 30:ajprenal.00321.2015. Review. Accepted (IF：3.248). 2. Li C#, Lin Y#, Luo R, Chen S, Wang F, Zheng P, Levi M, Yang T, Wang W*. Intrarenal Renin-Angiotensin System Mediates Fatty Acid-Induced ER Stress in the Kidney. Am J Physiol Renal Physiol. 2015 Dec 16, accepted (IF：3.248). 3. Wang W#,, Luo R#,, Lin Y, Wang F, Zheng P, Levi M, Yang T, Li C*. Aliskiren Restores Renal AQP2 Expression during Unilateral Ureteral Obstruction by Inhibiting the Inflammasome, Am J Physiol Renal Physiol. 2015 Apr 15;308(8):F910-22. (IF：3.248). 4. Li C and Wang W*, Urea transport mediated by water channel protein aquaporins. Subcell Biochem. 2014;73:227-65.（英文论著章节） 5. Li C, Wang W, Rivard C, Lanaspa M, Summer S, Schrier RW. Molecular mechanisms of angiotensin II stimulation on aquaporin-2 expression and trafficking. Am J Physiol Renal Physiol. 2011 May;300(5):F1255-61 6. Wang W, Li C, Summer SN, Falk S, Schrier RW. Interaction between vasopressin and angiotensin in vivo and in vitro: effect on aquaporins and urine concentration. Am J Physiol Renal Physiol. 2010 Sep; 299(3):F577-84 7. Li C, Wang W, Summer SN, Falk S, Schrier RW. Downregulation of UT-A1/UT-A3 is associated with urinary concentrating defect in glucocorticoid-excess state. J Am Soc Nephrol. 2008 Oct;19(10):1975-81. IF：9.343 8. Li C, Wang W, Summer SN, Westfall TD, Brooks DP, Falk S, Schrier RW. Molecular Mechanisms of Antidiuretic Effect of Oxytocin. J Am Soc Nephrol. 2008 Feb;19(2):225-32. IF：9.343 9. Li C, Wang W, Norregaard R, Knepper MA, Nielsen S, Frokiaer J. Altered expression of epithelial sodium channel (ENaC) in rats with bilateral or unilateral ureteral obstruction. Am J Physiol Renal Physiol. 2007 Jul;293(1):F333-41. 10. Li C, Wang W, Summer SN, Cadnapaphornchai MA, Falk S, Umenishi F, Schrier RW. Hyperosmolality In Vivo Upregulates Aquaporin 2 Water Channel and Na-K-2Cl Co-Transporter in Brattleboro Rats. J Am Soc Nephrol. 2006 Jun;17(6):1657-64 . IF：9.343 11. Li C, Shi Y, Wang W, Sardeli C, Kwon TH, Thomsen K, Jonassen T, Djurhuus JC, Knepper MA, Nielsen S, Frokiaer J. alpha-MSH prevents impairment in renal function and dysregulation of AQPs and Na-K-ATPase in rats with bilateral ureteral obstruction.Am J Physiol Renal Physiol. 2006 Feb;290(2):F384-96. 12.Li C, Klein JD, Wang W, Knepper MA, Nielsen S, Sands JM, Frokiaer J. Altered expression of urea transporters in response to ureteral obstruction. Am J Physiol Renal Physiol. 2004 Jun;286(6):F1154-62 13.Li C, Wang W, Kwon T-H, Knepper MA, Nielsen S, Frokiaer J. Altered expression of major renal Na transporters in rats with bilateral ureteral obstruction and release of obstruction. Am J Physiol Renal Physiol. 2003 Nov;285(5):F889-F901. 14.Li C, Wang W, Knepper MA, Nielsen S, Frokiaer J. Downregulation of renal aquaporins in response to unilateral ureteral obstruction. Am J Physiol Renal Physiol. 2003 May; 284(5): F1066-F1079. 15.Li C, Wang W, Kwon TH, Knepper MA, Nielsen S, Frokiaer J. Altered expression of major renal Na transporters in rats with unilateral ureteral obstruction. Am J Physiol Renal Physiol. 2003 Jan;284(1):F155-66. 16.Li C, Wang W, Kwon TH, Isikay L, Wen JG, Marples D, Djurhuus JC, Stockwell A, Knepper MA, Nielsen S, Frokiaer J. Downregulation of AQP1, -2, and -3 after ureteral obstruction is associated with a long-term urine-concentrating defect. Am J Physiol Renal Physiol. 2001 Jul;281(1):F163-71.