时光 - 中山大学 - 生命科学学院

个人简介

2013/08-至今，中山大学生命科学学院，讲师 2012/07-2013/07，中国科学院广州生物医药与健康研究院，华南干细胞与再生医学研究所，助理研究员 2007/09-2012/06，华东师范大学生命医学研究所博士 2003/09-2007/06，吉林师范大学生命科学学院学士

研究领域

1.表观遗传修饰和基因表达调控方向研究； 2.胚胎干细胞维持自我更新和分化的表观遗传学研究。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

(1) Fang Yu#, Guang Shi#, Shimeng Chen, Jiwei Chen, Shwu-Yuan Wu, Zhiqiang Wang, nansong xia, Yunhao Zhai, Zhenxing Wang, Yu Peng, Dong Wang, James X. Du, Lujian Liao, Sheng-Zhong Duan, Tieliu Shi, Jinke Cheng, Cheng-Ming Chiang, Jiwen Li, Jiemin Wong. SUMO Suppresses and MYC Amplifies Transcription Globally by Regulating CDK9 Sumoylation. Cell Research, 2018. Feb 11(Accepted). (2) Yang Hu#, Guang Shi# *, Laichen Zhang, Feng Li, Yuanling Jiang, Shuai Jiang, Wenbin Ma, Yong Zhao, Zhou Songyang, Junjiu Huang*. Switch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX. Scientific Report.2016. Aug 31; 6:32280. (3) Guang Shi#, Meng Wu#, Lan Fang, Fang Yu, Shimeng Cheng, Jiwen Li, James X. Du, Jiemin Wong*. PHD Finger Protein 2 (PHF2) Represses Ribosomal RNA Gene Transcription by Antagonizing PHD Finger Protein 8 (PHF8) and Recruiting Methyltransferase SUV39H1. Journal of Biological Chemistry. 2014. 289(43): 29691-700 (4) Jihui Qiu#, Guang Shi#, Yuanhui Jia#, Jing Li, Meng Wu, Jiwen Li, Shuo Dong, Jiemin Wong*, The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation. Cell Research, 2010. 20(8): 908-918. (5) Kaimeng Huang#, Xiaobai Zhang#, Jiejun Shi#, Mingze Yao, Jiannan Lin, Jiao Li, He Liu, Huanhuan Li, Guang Shi, Zhibin Wang, Biliang Zhang, Jiekai Chen, Guangjin Pan, Cizhong, Jiang, Duanqing Pei*, Hongjie Yao*. Dynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent cells. Scientific Reports. 2015, 5:17691. (6) Sijie Zhang#, Zhenhua Luo, Guang Shi, Dan Liu, Zhou Songyang*, Junjiu Huang*. TPP1 as a versatile player at the ends of chromosomes. Front. Biol 2014. (7) Junjiang Fu#, Jun Jiang, Jiwen Li, Shanshan Wang, Guang Shi, Qin Feng, Eileen White, Jun Qin, Jiemin Wong*. Deleted in breast cancer 1, a novel androgen receptor (AR) coactivator that promotes AR DNA-binding activity. Journal of Biological Chemistry, 2009. 284(11): 6832-6840.