个人简介
2016/01-至今,中山大学,生命科学学院,副教授 2013/04-2014/04,英国爱丁堡大学罗斯林研究所,国家公派访问学者 2010/07-2015/12,中山大学,生命科学学院,讲师 2008/07-2010/06,中山大学,生命科学学院,博士后,合作导师:陈瑶生教授 2003/09-2008/06,中国农业大学,生物学院,博士
近期论文
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1. Liu, X., H. Liu, M. Wang, R. Li, J. Zeng, D. Mo, P. Cong, X. Liu, Y. Chen and Z. He (2018). "Disruption of the ZBED6 binding site in intron 3 of IGF2 by CRISPR/Cas9 leads to enhanced muscle development in Liang Guang Small Spotted pigs." Transgenic Res. 2. Yuan, P., Z. He, S. Sun, Y. Li, W. Wang, X. Liang, X. Xie, Y. Jiang and D. Yang (2018). "Bi-allelic recessive loss-of-function mutations in FIGLA cause premature ovarian insufficiency with short stature." Clin Genet. 3. Liu, X., M. Wang, Y. Qin, X. Shi, P. Cong, Y. Chen and Z. He (2018). "Targeted integration in human cells through single crossover mediated by ZFN or CRISPR/Cas9." BMC Biotechnol 18(1): 66. 4. Yuan P, He Z, Zheng L, Wang W, Li Y, Zhao H, Zhang VW, Zhang Q, Yang D. 2017. Genetic evidence of 'genuine' empty follicle syndrome: a novel effective mutation in the LHCGR gene and review of the literature. Hum Reprod 32:944-953. 5. Nie Y, Cong P, Liu X, Wang M, Chen Y, He Z. 2017. Development of a bacterial-based negative selection system for rapid screening of active single guide RNAs. Biotechnol Lett 39:351-358. 6. He Z, Shi X, Liu M, Sun G, Proudfoot C, Whitelaw CB, Lillico SG, Chen Y. 2016. Comparison of surrogate reporter systems for enrichment of cells with mutations induced by genome editors. J Biotechnol 221:49-54. 7. He Z, Proudfoot C, Whitelaw CB, Lillico SG. 2016. Comparison of CRISPR/Cas9 and TALENs on editing an integrated EGFP gene in the genome of HEK293FT cells. Springerplus 5:814. 8. He Z, Shi X, Du B, Qin Y, Cong P, Chen Y. 2015. Highly efficient enrichment of porcine cells with deletions induced by CRISPR/Cas9 using dual fluorescence selection. J Biotechnol 214:69-74. 9. He Z, Proudfoot C, Mileham AJ, McLaren DG, Whitelaw CB, Lillico SG. 2015. Highly efficient targeted chromosome deletions using CRISPR/Cas9. Biotechnol Bioeng 112:1060-1064.