方坚鸿 - 中山大学 - 生命科学学院

个人简介

教育经历 2008.9-2013.6博士中山大学 2004.9-2008.6学士中山大学工作经历 2017.1-present副教授 2013.7-2017.1 讲师

研究领域

肿瘤血管生成及转移调控机制

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. JH Fang#, L Xu#, LR Shang#, CZ Pan, J Ding, YQ Tang, H Liu, CX Liu, JLZheng, YJ Zhang, ZG Zhou, J Xu, L Zheng, MS Chen*, SM Zhuang*. Vessels that encapsulate tumor clusters (VETC) pattern is a predictor of sorafenib benefit in patients with hepatocellular carcinoma. Hepatology. Accepted. (IF 14.2) 2. JH Fang*, ZJ Zhang, LR Shang, YW Luo, YF Lin, Y Yuan*, SM Zhuang*. Hepatoma cell-secreted exosomal microRNA-103 increases vascular permeability and promotes metastasis by targeting junction proteins. Hepatology. 2018,68(4):1459-1475. (Research Highlights, IF 14.2) 3. XJ Lin#, JH Fang#, XJ Yang, C Zhang, Y Yuan, L Zheng, SM Zhuang*. Hepatocellular Carcinoma Cell-Secreted Exosomal MicroRNA-210 Promotes Angiogenesis In Vitro and In Vivo. Mol Ther Nucleic Acids. 2018,1;11:243-252 (IF 6.4) 4. JH Fang#, ZY Zheng#, JY Liu, C Xie, ZJ Zhang, SM Zhuang*. Regulatory Role of the MicroRNA-29b-IL-6 Signaling in the Formation of Vascular Mimicry. Molecular Therapy: Nucleic Acids 2017,8:90-100 (IF 6.4) 5. HC Zhou#, JH Fang#, LR Shang, ZJ Zhang, Y Sang, L Xu, Y Yuan, MS Chen, L Zheng, Y Zhang, SM Zhuang*. MicroRNA-125b and microRNA-100 suppress metastasis of hepatocellular carcinoma by disrupting the formation of vessels that encapsulated tumour clusters. J Pathol. 2016.240(4):450-460 (Shared First Authorship, IF 6.9) 6. C Zhang, M Wu, L Zhang, LR Shang, JH Fang*, SM Zhuang*. Fibrotic microenvironment promotes the metastatic seeding of tumor cells via activating the fibronectin 1/secreted phosphoprotein 1-integrin signaling. Oncotarget 2016,7 (29): 45702-45714 (Shared Corresponding Authorship, IF 5.2) 7. JH Fang#, HC Zhou#, C Zhang, LR Shang, L Zhang, J Xu, L Zheng, Y Yuan, RP Guo, WH Jia, JP Yun, MS Chen, Y Zhang, SM Zhuang*. A novel vascular pattern promotes metastasis of hepatocellular carcinoma in an EMT-independent manner. Hepatology 2015,62(2):452-65 (Cover Article, Research Highlights, Editorial, IF 14.2) 8. HC Zhou#, JH Fang#, X Luo, L Zhang, J Yang, C Zhang, SM Zhuang*. Downregulation of MicroRNA-100 Enhances the ICMT-Rac1 Signaling and Promotes Metastasis of Hepatocellular Carcinoma Cells. Oncotarget 2014,5(23):12177-88 (Shared First Authorship, IF 5.2) 9. JH Fang, HC Zhou, C Zeng, J Yang, Y Liu, X Huang, JP Zhang, XY Guan, SM Zhuang*.MicroRNA-29b suppresses tumor angiogenesis, invasion and metastasis by regulating MMP-2 expression. Hepatology 2011,54(5):1729-40 (Highly Cited Papers based on ESI, IF 14.2) 10. Y Xiong#, JH Fang#, JP Yun, J Yang, Y Zhang, WH Jia, SM Zhuang*. Effects of microRNA-29 on apoptosis, tumorigenicity and prognosis of hepatocellular carcinoma. Hepatology 2010, 51(3): 836-45 (Shared First Authorship, Highly Cited Papers based on ESI, IF 14.2)