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个人简介

1998至2002年就读于上海交通大学动力与能源工程学院,获核工程与核技术专业学士学位。2002至2007年在中国科学技术大学近代物理系金革教授实验室攻读博士期间参与国家大科学工程项目"大天区面积多目标光纤光谱望远镜"(LAMOST),并承担其中的巡天战略系统的研发工作,在计算机算法和大型工程软件设计开发方面具有丰富的经验。2007年7月获得物理电子学工学博士学位之后进入中国科学技术大学生命科学学院温龙平研究组进行博士后研究工作,将计算机和天文学算法以及工程学思想成功运用到生物信息学领域,在蛋白质组生物信息学方面取得了丰富成果。主要包括设计出高效的GPS(Group-based Prediction System)预测算法,并基于该算法开发出十多种蛋白质翻译后修饰位点预测工具,此外还构建多个蛋白质相关数据库及辅助工具。2010 年3月获中山大学生命科学学院“百人计划”引进,2011年12月晋升教授。 1998.09 – 2002.07 学士 上海交通大学动力与能源工程学院核工程与自动化专业 2002.09 – 2007.06 博士 中国科学技术大学近代物理系物理电子学专业 2007.07 – 2010.03 博士后 中国科学技术大学生命科学学院 2010.03 – 2011.12 副教授 中山大学生命科学学院 2011.12 – 今 教授中山大学生命科学学院 2012.05 – 今 部长 高性能计算2011协同创新中心应用研发部 2012.11 – 今 主任 中山大学生命科学学院生物信息学中心 2014.07– 今 教授(双聘) 中山大学肿瘤防治中心

研究领域

主要从事生物大分子修饰(蛋白质翻译后修饰,RNA修饰)、基因编辑、肿瘤基因组学和生物图像识别相关生物信息学与实验研究。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Ren J, Wen LP, Gao XJ, Jin CJ, Xue Y, Yao XB. DOG 1.0: illustrator of protein domain structures. Cell Research. 2009;19(2):271-273. (IF: 15.606, cited by 195) 2. Zhao Q, Xie YB, Zheng YY, Jiang S, Liu WZ, Mu WP, Liu ZX, Zhao Y, Xue Y* and Ren J*. GPS-SUMO: a tool for the prediction of sumoylation sites and SUMO-interaction motifs. Nucleic Acids Research. 2014;42(W1): W325-330. (IF: 10.162, cited by 99,ESI HCP) 3. Liu WZ, Xie YB, Ma JY, Luo XT, Nie P, Zuo ZX, Lahrmann U, Zhao Q, Zheng YY, Zhao Y, Xue Y* and Ren J*. IBS: an illustrator for the presentation and visualization of biological sequences. Bioinformatics. 2015; 31(20):3359-3361(IF: 7.307, cited by 65,ESI Hot Paper) 4. Zheng YY, Nie P, Peng D, He ZH, Liu MN, Xie YB, Miao YY, Zuo ZX* and Ren J*. m6AVar: a database of functional variants involved in m6A modification. Nucleic Acids Research. 2018; 46(D1): D139-145 (IF: 10.162) 5. Ren J, Wen LP, Gao XJ, Jin CJ, Xue Y, Yao XB. CSS-Palm 2.0: an updated software for palmitoylation sites prediction. Protein Eng Des Sel. 2008;21(11):639-644. (IF: 3.023, cited by 246,ESI HCP) 6. Xue Y#, Ren J#, Gao XJ, Jin CJ, Wen LP, Yao XB. GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy. Molecular & Cellular Proteomics. 2008;7(9):1598-1608. ( IF: 8.834, cited by 339) 7. Ren J, Gao XJ, Jin CJ, Zhu M, Wang XW, Shaw A, Wen LP, Yao XB, Xue Y. Systematic study of protein sumoylation: Development of a site-specific predictor of SUMOsp 2.0. Proteomics. 2009;9(12):3409-3412. (IF: 4.815, cited by 140) 8. Xue Y*, Liu ZX, Gao XJ, Jin CJ, Wen LP, Yao XB, Ren J*. GPS-SNO: Computational Prediction of Protein S-Nitrosylation Sites with a Modified GPS Algorithm. Plos One. 2010;5(6): e11290. (IF: 4.411, cited by 90) 9. Xue Y*, Liu ZX, Cao J, Ma Q, Gao X, Wang QQ, Jin CJ, Zhou YH, Wen LP, Ren J*. GPS 2.1: enhanced prediction of kinase-specific phosphorylation sites with an algorithm of motif length selection. Protein Eng Des Sel. 2011;24(3):255-260. (IF: 3.023, cited by 91) 10. Ren J, Jiang CH, Gao XJ, Liu ZX, Yuan ZN, Jin CJ, Wen LP, Zhang ZL, Xue Y, Yao XB. PhosSNP for Systematic Analysis of Genetic Polymorphisms That Influence Protein Phosphorylation. Molecular & Cellular Proteomics. 2010;9(4):623-634. (IF: 8.354, cited by 46) 11. Ren J, Liu ZX, Gao XJ, Jin CJ, Ye ML, Zou HF, Wen LP, Zhang ZL, Xue Y, Yao XB. MiCroKit 3.0: an integrated database of midbody, centrosome and kinetochore. Nucleic Acids Research. 2010;38(D1):D155-D160. (IF: 10.162, cited by 16) 12. Xie YB, Zheng YY, Li HY, Luo XT, He ZH, Cao S, Shi Y, Zhao Q, Xue Y, Zuo ZX, Ren J*. GPS-Lipid: a robust tool for the prediction of multiple lipid modification sites. Scientific Reports. 2016;6:28249. (IF: 5.228, cited by 15) 13. Liu ZX, Cao J, Gao XJ, Zhou YH, Wen LP, Yang X, Yao XB, Ren J*, Xue Y*. CPLA 1.0: an integrated database of protein lysine acetylation. Nucleic Acids Research. 2011; 39(D1):D1029-1034. (IF: 10.162, cited by 27) 14. Xie SQ, Nie P, Wang Y, Wang H, Li H, Yang Z, Liu Y*, Ren J*, Xie Z*. RPFdb: a database for genome wide information of translated mRNA generated from ribosome profiling. Nucleic Acids Research. 2016;44(D1):D254-D258. (IF: 10.162, cited by 13) 15. Song CX, Ye ML, Jiang XN, Han GH, Songyang Z, Tan YX, Wang HY, Ren J*, Xue Y* & Zou HF*. Systematic analysis of protein phosphorylation networks from phosphoproteomic data. Molecular & Cellular Proteomics. 2012;11(10):1070-1083. (IF: 7.398, cited by 58) 16. Liu ZX#, Ren J#, Cao J#, He J, Yang Q, Ma Q, Gao XJ, Yao XB, Jin CJ, Xue Y. Systematic analysis of the Plk-mediated phosphoregulation in eukaryotes. Briefings in Bioinformatics. 2013;14 (3):344-360 (IF: 8.399, cited by 11) 17. Xue Y*, Gao XJ, Cao J, Liu ZX, Jin CJ, Wen LP, Yao XB, Ren J*. A Summary of Computational Resources for Protein Phosphorylation. Current Protein & Peptide Science. 2010;11(6):485-496. (IF: 3.83, cited by 38) 18. Zheng YY, Guo JJ, Li X, Xie YB, Hou MM, Fu XY, Dai SK, Diao RC, Miao YY* and Ren J*. An integrated overview of spatiotemporal organization and regulation in mitosis in terms of the proteins in the functional supercomplexes. Frontiers in Microbiology. 2014;5:573 (IF: 4.076) 19. Xie YB, Luo XT, He ZH, Zheng YY, Zuo ZX, Zhao Q*, Miao YY* and Ren J*. VirusMap: A visualization database for the influenza A virus. Journal of Genetics and Genomics. 2017;44(4):281-284. (IF: 4.051) 20. Liu ZX, Gao X, Ma Q, Cao J, Ren J*, Xue Y*. GPS-CCD: A novel computational program for prediction of calpain cleavage sites. Plos One.2011;6(4):e19001. (IF: 4.411, cited by 38) 21. Liu ZX, Cao J, Ma Q, Gao XJ, Ren J*, Xue Y*. GPS-YNO2: computational prediction of tyrosine nitration sites in proteins. Mol Biosyst. 2011;7(4):1197-1204. (IF: 3.825, cited by 35) 22. Liu ZX, Ma Q, Cao J, Gao XJ, Ren J*, Xue Y*. GPS-PUP: computational prediction of pupylation sites in prokaryotic proteins. Mol Biosyst. 2011;7(10):2737-2740. (IF: 3.825, cited by 24) 23. Ren J, Gao XJ, Liu ZX, Cao J, Ma Q, Xue Y. Computational Analysis of Phosphoproteomics: Progresses and Perspectives. Current Protein & Peptide Science. 2011;7(12):591-601.(IF: 3.83, cited by 11)

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