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细菌耐药与逆转调节的代谢机制 宿主抗耐药菌感染的代谢机制

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Yang J, Cheng ZX#, Zeng ZH, Yang MJ, Li D, Lai SS, Peng XX, Li H*. NaCl promotes antibiotic resistance through reducing redox states in Vibrio alginolyticus. Environ. Microbiol. 2018,in press Peng B, Lin XP, Wang SN, Yang MJ, Peng XX, Li H*. Polyvalent protective immunogens identified from outer membrane proteins of Vibrio parahaemolyticus and their induced innate immune response. Fish Shellfish Immunol. 2018,72:104-110 Wang SN, Cheng ZX, Ling XP, Chu X, Peng XX*, Li H* Construction, immune protection and innate immune response of shuffled polyvalent ompAs vaccines. Fish Shellfish Immunol. 2018,74:325-331 Su YB#, Peng B#, Li H#, Cheng ZX#, Zhang TT, Zhu JX, Li D, Li MY, Ye JZ, Du CC, Zhang S, Zhao XL, Yang MJ, Peng XX*. Pyruvate cycle increases aminoglycoside efficacy and provides respiratory energy in bacteria. PNAS 2018,115 (7): E1578-E1587 Cheng ZX, Chu X, Wang SN, Peng XX*, Li H*. Six of ompA genes family shuffling for development of polyvalent vaccines against Vibrio alginolyticus and Edwardsiella tarda. Fish Shellfish Immunol. 2018,75:308-315 Yang MJ, Cheng ZX, Jiang M, Zeng ZH, Peng B, Peng XX, Li H*. Boosted TCA cycle enhances survival of zebrafish to Vibrio alginolyticus infection. Virulence,2018.9(1):634-644 Zhang DF, Ye JZ, Dai HH, Lin XM, Li H*, Peng XX*. Identification of ethanol tolerant outer membrane proteome reveals OmpC-dependent mechanism in a manner of EnvZ/OmpR regulation in Escherichia coli. J Proteomics 2018,179:92-99 Cheng ZX, Yang MJ, Peng B, Peng XX, Lin XM*, Li H*. The depressing central carbon and energy metabolisms mediate levofloxacin resistance in Vibrio alginolyticus. J Proteomics 2018, 181:83-91 Liu X, Yang MJ, Li H*, Peng XX*. Differential antibody responses to outer membrane proteins contribute to differential immune protections between live and inactivated Vibrio parahaemolyticus. J Proteome Res. 2018,17:2987-2994 Li H#, Zhu QF#, Peng XX, Peng B*. Interactome of E. piscicida and grouper liver proteins reveals strategies of bacterial infection and host immune response. Sci. Rep.2017, 7:39824 Li H#*, Chu X, Li D, Zeng ZH, Peng XX*. Construction and immune protection evaluation of recombinant polyvalent OmpAs derived from genetically divergent ompA by DNA shuffling. Fish Shellfish Immunol.2016,49:230-236 Peng B#, Su YB#, Li H#, Han Y, Guo C, Tian YM, Peng XX*. Exogenous alanine and/or Glucose plus kanamycin kills antibiotic-resistant bacteria. Cell Metab. 2015, 21(2):249-261 Peng B, Ma YM, Zhang JY, Li H*. Metabolome strategy against Edwardsiella tarda infection through glucose-enhanced metabolic modulation in tilapias. Fish Shellfish Immunol. 2015,45:869-876 Ma YM, Yang MJ, Wang SY, Li H*, Peng XX*. Liver functional metabolomics discloses an action of L-leucine against Streptococcus iniae infection in tilapias. Fish Shellfish Immunol. 2015,45:414-421 Peng B, Li H, Peng XX*. Functional metabolomics: from biomarker discovery to metabolome reprogramming. Protein cell 2015,6(9):628-637 Guo C, Peng B, Song M, Wu CW, Yang MJ, Zhang JY, Li H*. Live Edwardsiella tarda vaccine enhances innate immunity by metabolic modulation in zebrafish. Fish Shellfish Immunol. 2015,47(2):664-673 Zhao XL, Wu CW, Peng XX*, Li H*. Interferon-α2b against microbes through promoting biosynthesis of unsaturated fatty acids. J Proteome Res. 2014,13(9):4155-4163 Cheng ZX, Ma YM, Li H*, Peng XX*. N-acetylglucosamine enhances survival ability of tilapias infected by Streptococcus iniae. Fish Shellfish Immunol. 2014,40:524-530 Song M, Xie J, Peng XX, Li H*. Identification of protective immunogens from extracellular secretome of Edwardsiella tarda. Fish Shellfish Immunol. 2013,35(6): 1932-1936 Liu X, She XT, Zhu QF, Li H*, Peng XX*. Heterogeneous interactome between Litopenaeus vannamei plasma proteins and Vibrio parahaemolyticus outer membrane proteins. Fish Shellfish Immunol. 2013,34(1):192-198 Zhang HL, Liu XJ, Zhang BW, Peng XX, Li H*. Amphioxus CaVPT and creatine kinase are crucial immune-related molecules in response to bacterial infection and mmunization. Fish Shellfish Immunol. 2012, 33:1139-1148 Li H, Pan JY, Liu XJ, Gao JX, Wu HK, Wang C, Peng XX*.Alterations of protein complexes and pathways in genetic information flow and response to stimulus contribute to Escherichia coli resistance to balofloxacin. Mol. BioSyst. 2012, 8, 2303–2311 Lin XM, Wang C, Guo C, Tian YM, Li H*, Peng XX*. Differential regulation of OmpC and OmpF by AtpB in Escherichia coli exposed to nalidixic acid and chlortetracycline. J Proteomics 2012,75:5898-5910 Li PP, Liu XJ, Li H, Peng XX*. Downregulation of Na(+)–NQR complex is essential for Vibro Alginolyticus in resistance to balofloxacin. J Proteomics 2012; 75(4):2638-2648

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