个人简介
2017年-至今 中山大学生命科学学院 教授 2015-2017 加拿大农业部 伦敦研发中心 研究科学家 2015 加拿大the University of Western Ontario生物系 博士后 2010-2014 加拿大the University of Western Ontario生物系 博士 2006-2009 中山大学生命科学学院 硕士
研究领域
表观遗传的生物信息学分析。 基因表达调控的表观遗传机制。 染色体重塑因子识别靶标基因的分子机理。 种子寿命与活力的表观遗传调控。
近期论文
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Hung FY, Chen FF, Li C, Chen C, Lai YC, Chen JH, Cui Y, Wu K. (2018) The Arabidopsis LDL1/2-HDA6 histone modification complex is functionally associated with CCA1/LHY in regulation of circadian clock genes. Nucleic Acids Research. doi: 10.1093/nar/gky749 Li C#*, Chen C*, Chen H, Wang S, Chen X, and Cui Y. (2018) Verification of DNA motifs in Arabidopsis using CRISPR/Cas9 mediated mutagenesis. Plant Biotechnology Journal. *: co-first author; #: Corresponding author Chen C*, Li C*, Wang Y, Tian G, Saatian B, Nguyen V, Hannoufa A, Austin R. S., Kohalmi S.E., Wu K, Huang S and Cui Y. (2017) Cytosolic acetyl-CoA promotes histone H3 lysine 27 acetylation in Arabidopsis. Nature Plants 3, 814–824. *: co-first author Li C and Cui Y. (2016) A DNA element that remembers winter. Nature Genetics 48(12): 1451-1452. Li C,Gu L, Gao L, Chen C,Wei, C-Q, Qi Q, Chien C-W, Wang S, Jiang L, Ai L-F, Chen C-Y, Yang S,Nguyen V, Qi Y, Snyder M.P., Burlingame A.L., Kohalmi S.E., Huang S, Cao X, Wang Z-Y., Wu K, Chen X, and Cui Y. (2016) Concerted genomic targeting of H3K27 demethylase REF6 and chromatin-remodeling ATPase BRM in Arabidopsis. Nature Genetics 48(6): 687-693. doi:10.1038/ng.3555. Xu Y, Guo C, Wang H, Zhou B, Zheng B, Ding H, Zhu Z, Peragine A, Poethig R, S, Li C, Cui Y and Wu G. (2016) Regulation of vegetative phase change by SWI2/SNF2 chromatin remodeling ATPase BRAHMA in Arabidopsis. Plant Physiology 172:2416-2428. Li C, Chen C,Gao L, Yang S, Nguyen V, Shi X, Siminovitch K, Kohalmi S.E., Huang S, Wu K, Chen X, and Cui Y. (2015) The Arabidopsis SWI2/SNF2 chromatin remodeler BRAHMA regulates polycomb function during vegetative development and directly activates the flowering repressor gene SVP. PLoS Genetics 11(1): e1004944. Yang S*, Li C*, Zhao L*, Gao S, Lu J, Zhao M, Chen C-Y, Liu X, Luo M, Cui Y, Yang C and Wu K. (2015) The Arabidopsis SWI2/SNF2 chromatin remodeling ATPase BRAHMA targets directly to PINs and is required for root stem cell niche maintenance. Plant Cell 27:1670-1680. *: co-first author Zhao M, Yang S, Chen C-Y, Li C, Shan W, Lu W, Cui Y, Liu X, and Wu K. (2015) Arabidopsis BREVIPEDICELLUS interacts with the SWI2/SNF2 chromatin remodeling ATPase BRAHMA to regulate KNAT2 and KNAT6 expression in control of inflorescence architecture. PLoS Genetics 11(3): e1005125. Zhou Y, Tan B, Luo M, Li Y, Liu C, Chen C, Yu CW, Yang S, Dong S, Ruan J, Yuan L, Zhang Z, Zhao L, Li C, Chen H, Cui Y, Wu K, and Huang S. (2013) HISTONE DEACETYLASE19 interacts with HSL1 and participates in the repression of seed maturation genes in Arabidopsis seedlings. Plant Cell 25:134-148. Elhiti M, Hebelstrup KH, Wang A, Li C, Cui Y, Hill RD, and Stasolla C. (2013) Function of type-2 Arabidopsis hemoglobin in the auxin-mediated formation of embryogenic cells during morphogenesis. Plant Journal 74: 946-958. Fu G, Zhong Y, Li C, Li Y, Lin X, Liao B, Tsang EW, Wu K, and Huang S. (2010) Epigenetic regulation of peanut allergen gene Ara h 3 in developing embryos. Planta 231:1049-1060. Li C*, Wu K*, Fu G, Li Y, Zhong Y, Lin X,Zhou Y, Tian L, and Huang S. (2009) Regulation of oleosin expression in developing peanut (Arachis hypogaea L.) embryos through nucleosome loss and histone modifications. Journal of Experimental Botany 60: 4371-4382. *: co-first author.