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个人简介

2004年 获中山大学理学学士学位; 2009年 获中山大学理学博士学位,破格晋升中山大学副教授; 2011年 入选教育部新世纪优秀人才支持计划; 2012年 晋升教授,博士生指导教师, 入选首批中山大学优秀青年教师培养计划 ; 2013年 获广东省自然科学杰出青年基金项目资助; 2014年 获国家优青项目资助,入选首批广东省特支计划青年拔尖人才,入选广东省高等学校优秀青年教师培养计划; 2016年 获聘教育部长江青年学者,获聘广东省珠江学者特聘教授; 2017年 入选中组部万人计划青年拔尖人才,广东省特支计划千百万领军人才。

研究领域

肿瘤免疫编辑与疾病进展; 炎性免疫微环境; B细胞生物学功能; 肿瘤相关体液免疫反应网络。

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

【1】Wei Y, Lao XM, Xiao X, Wang X, Wu ZJ, Zeng QH, Wu CY, Wu RQ, Chen ZX, Zheng L, Li B, Kuang DM*. 2019. Plasma Cell Polarization to the Immunoglobulin G Phenotype in Hepatocellular Carcinomas Involves Epigenetic Alterations and Promotes Hepatoma Progression in Mice. Gastroenterology, in press.(IF:20.8). 【2】Ouyang FZ, Wu RQ, Wei Y, Liu RX, Yang D, Xiao X, Zheng L, Li B, Lao XM*, Kuang DM*. 2017. Dendritic cell-elicited B-cell activation fosters immune privilege via IL-10 signals in hepatocellular carcinoma. Nat Commun 7:13453.(IF:12.4). 【3】Chen MM, Xiao X, Lao XM, Wei Y, Liu RX, Zeng QH, Wang JC, Ouyang FZ, Chen DP, Chan KW, Shi DC, Zheng L, Kuang DM*. 2016. Polarization of Tissue-Resident TFH-Like Cells in Human Hepatoma Bridges Innate Monocyte Inflammation and M2b Macrophage Polarization. Cancer Discov 6:1182-95.(IF:24.4)杂志评述 【4】 Xiao X, Lao XM, Chen MM, Liu RX, Wei Y, Ouyang FZ, Chen DP, Zhao XY, Zhao Q, Li XF, Liu CL, Zheng L, Kuang DM*. 2016. PD-1hi Identifies a Novel Regulatory B-cell Population in Human Hepatoma That Promotes Disease Progression. Cancer Discov 6:546-59.(IF:24.4)杂志评述,专家亮点评述 【5】 Liu RX, Wei Y, Zeng QH, Chan KW, Xiao X, Zhao XY, Chen MM, Ouyang FZ, Chen DP, Zheng L, Lao XM, Kuang DM*. 2015. Chemokine (C-X-C motif) receptor 3-positive B cells link interleukin-17 inflammation to protumorigenic macrophage polarization in human hepatocellular carcinoma. Hepatology 62:1779-90.(IF:14.1)主编推送 【6】Kuang DM*, Xiao X, Zhao Q, Chen MM, Li XF, Liu RX, Wei Y, Ouyang FZ, Chen DP, Wu Y, Lao XM, Deng H, Zheng L*. 2014. B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets. J Clin Invest 124:4657-67. (IF:13.3)F1000推荐 【7】Kuang DM, Zhao Q, Wu Y, Peng C, Wang J, Xu Z, Yin XY, Zheng L*. 2011. Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma. J Hepatol 54:948-55.(IF:14.9)专家亮点评述,ESI高被引论文 【8】Kuang DM, Peng C, Zhao Q, Wu Y, Chen M, Zheng L*. 2010. Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote the expansion of memory T helper 17 cells. Hepatology 51:154-64.(IF:14.1) 【9】Kuang DM, Zhao Q, Peng C, Xu J, Zhang JP, Wu C, Zheng L*. 2009. Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1. J Exp Med 206:1327-37.(IF:10.8)ESI高被引论文 【10】Kuang DM, Wu Y, Chen N, Cheng J, Zhuang SM, Zheng L. 2007. Tumor-derived hyaluronan induces formation of immunosuppressive macrophages through transient early activation of monocytes. Blood 110:587-95. (IF:15.1)

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