陈海洋 - 中山大学 - 生命科学学院

个人简介

教育经历： 1.2005/9–2010/7，中国科学院遗传与发育生物学研究所，发育生物学，博士，导师：黄勋 2.2001/9–2005/7，新疆大学，生物科学，学士科研与学术工作经历： 1.2015/9-至今，中山大学，生命科学学院，教授 2.2011/4-2015/7，美国约翰霍普金斯大学—卡内基科学研究所胚胎学部，博士后，合作导师：郑诣先 3.2010/8-2011/4，四川省人民医院，器官及细胞移植研究所，研究助理

研究领域

1、干细胞在器官建成、组织损伤再生及衰老过程中的功能调控机理; 2、干细胞功能异常诱发个体衰老及衰老相关疾病发生的生物学机制研究；

近期论文

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Haiyang Chen, Xiaobin Zheng, Danqin Xiao, Yixian Zheng. 2016. Age-associated de-repression of retrotransposons in the Drosophila fat body, its potential cause and consequence. Aging Cell. Volume 15, Issue 3, p542-52. Haiyang Chen, Xiaobin Zheng and YixianZheng. (2015). Lamin-B in systemic inflammation, tissue homeostasis, and aging. Nucleus; Apr 15:1-4; Yihan Wan, Xiaobin Zheng, Haiyang Chen, Yuxuan Guo, Hao Jiang, Xiaonan He, Xueliang Zhu, and Yixian Zheng. (2015). Splicing function of mitotic regulators links R-loop-mediated DNA damage to tumor cell killing. Journal of Cell Biology; vol. 209 no.2 235-246 ; Haiyang Chen, Xiaobin Zheng, Yixian Zheng. (2014). Systemic inflammation due to lamin-B loss in old Drosophila causes gut hyperplasia. Cell, 2014 Nov 6;159(4):829-43. Haiyang Chen, Yixian Zheng. (2014). Nuclear lamina builds tissues from the stem cell niche. Fly, 2014; 8:0 - -1. Extra view. Haiyang Chen, Xin Chen, Yixian Zheng. (2013). The Nuclear Lamina Regulates Germline Stem Cell Niche Organization via Modulation of EGFR Signaling. Cell Stem Cell, Volume 13, Issue 1, 3 July 2013, Pages 73–86. Haiyang Chen, Zhonghua Liu, Xun Huang. (2010). Drosophila models of peroxisomal biogenesis disorder: Peroxins are required for spermatogenesis and very long chain fatty acid metabolism. Human Molecular Genetics, 2010, 19(3):494-505. Haiyang Chen, Zhiguo Ma, Zhonghua Liu, Yuan Tian, Yanhui Xiang, Chao Wang, Matthew P. Scott, and Xun Huang. (2009). Case Studies of Ends-Out Gene Targeting in Drosophila. Genesis, 2009, 47(5):305-8. Bi, J., Xiang, Y., Haiyang Chen, Liu, Z., Gronke, S., Kuhnlein, R. P. and Huang, X. (2012). Opposite and redundant roles of the two Drosophila Perilipins in lipid mobilization. J Cell Sci. 2012 Aug 1;125(Pt 15):3568-77. Zhou, B., Yang, L., Li, S., Huang, J., Haiyang Chen, Hou, L., Wang, J., Green, C.D., Yan, Z., Huang, X., et al. (2012). Midlife gene expressions identify modulators of aging through dietary interventions. Proc Natl Acad Sci U S A 109, E1201-1209. Tuxworth, R.I., Haiyang Chen, Vivancos, V., Carvajal, N., Huang, X., and Tear, G. (2011). The Batten disease gene CLN3 is required for the response to oxidative stress. Human Molecular Genetics, 20, 2037-2047. Song, S., Ge, Q., Wang, J., Haiyang Chen, Tang, S., Bi, J., Li, X., Xie, Q., and Huang, X. (2011). TRIM-9 functions in the UNC-6/UNC-40 pathway to regulate ventral guidance. J Genet Genomics 38, 1-11.