个人简介
1994年于吉林医学院预防医学专业毕业，获医学学士学位 1999年于中国科学院微生物研究所研究生毕业，获理学硕士学位 2002年于德国杜塞尔多夫大学儿童血液肿瘤研究所，获得医学博士学位 2002 -2005 中国科学院微生物研究所工作 科研工作 助理研究员 2005-2007 中国科学院大学生命科学院 教学与科研工作 讲师 2007-2014 中国科学院大学生命科学院 教学与科研工作 副教授 2014-至今 中山大学 教学与科研工作 副教授
研究领域
纳米材料做为疫苗佐剂及载体的研究，纳米材料在自身免疫性疾病治疗中应用研究。
近期论文
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1. Xing Y, Chu Q, Feng R, Wang W, Liu L*, Lu Z*. hCLP46 increases Smad3 protein stability via inhibiting its ubiquitin-proteasomal degradation. Protein Cell. 2015 Jun 10
2. Zhang S, Bai R, Feng R, Zhang H, Liu LX*. Detection and evolutionary analysis of picobirnaviruses in treated wastewater. Microb Biotechnol. 2014, Dec 27. doi: 10.1111/1751-7915.12239
3. Wang, J.; Liu, L.X.*; Zhu, W.; Chen, Y.M.*; Wang, C.* “Cancer Cell Uptake of Polymer Hydrogel Nanotubes”, J. Biomed. Nanotechnol. 2014, 10, 3329-3336.
4. Qiaoyun Chua, Lixin Liua,* and Wei Wang*. Overexpression of hCLP46 enhances Notch activation and regulates cell proliferation in a cell type-dependent manner. Cell Prolif. 2013, 46, 254-62.
5. Ru Bai, Xing-Jie Zhang, Yan-Li Li, Jing-Ping Liu, Hong-Bin Zhang, Wei-Lie Xiao, Jian-Xin Pu, Han-Dong Sun, Yong-Tang Zheng, and Li-Xin Liu .SJP-L-5, a novel small-molecule compound, inhibits HIV-1 infection by blocking viral DNA nuclear entry. BMC Microbiology (2015) 15:274-287.
6. Zhao, P.; Yan, Y. C.; Feng, X. Q.; Liu, L. X.;* Wang, C.; Chen, Y. M.* Highly efficient synthesis of polymer brushes with PEO and PCL as side chains via click chemistry. Polymer, 53(2012)1992-2000.
7. Zhao, P.; Liu, L. X.;* Feng, X. Q.; Wang, C.;* Shuai, X. T.; Chen, Y. M.* Molecular Nanoworm with PCL Core and PEO Shell as Non-spherical Carrier for Drug Delivery. Macromol. Rapid Commun. 33(2012):1351-5
8. Yanli Li, Guangxia Gao, Yongtang Zheng, Lixin Liua,*. A simple method for exploring the mechanisms for anti-HIV compounds. Int J Infect Dis 2010,14:S77-S77
9. Zhu, W.; Li, Y. L.; Liu, L. X.;* Chen, Y. M.;* Wang, C.; Xi, F. Biamphiphilic triblock copolymer micelles as a multifunctional platform for anticancer drug delivery. J. Biomed. Mater. Res. Part A. 96A (2011) 330-340.
10. Zhang, W. L.; Li, Y. L.; Liu, L. X.*; Sun, Q.; Shuai, X. T.; Zhu, W.; Chen, Y. M.* Amphiphilic Toothbrush-like Copolymers Based on Poly(ethylene glycol) and Poly(ε-caprolactone) as Drug Carriers with Enhanced Properties. Biomacromolecules 11 (2010) 1331-1338.
11. Zhu, W.; Li, Y. L; Liu, L. X.*; Zhang, W.; Chen, Y. M.*; Xi, F. Supramolecular Hydrogels from Cisplatin-Loaded Block Copolymer Nanoparticles and α-Cyclodextrins with a Stepwise Delivery Property. Biomacromolecules. 11 (2010) 3086-3092.
12. Li, Z. Q.; Liu, L. X.; Lv, F. X.; Ma, J.; Gao, G. X.* Fusing ZAP to HIV RNA binding proteins to inhibit HIV. Progress in Biochemistry and Biophysics 34 (2007) 50-56.
13. Ye, J.; Liu, L. X.; Gao, G. X.;* Fang, R. X.* Inhibition of SARS by small interfering RNAs targeting the leader RNA. Progress in Biochemistry and Biophysics 34 (2007) 1092-1100. (共为第一作者)
14. Borrowski, A.;* Dirkson, U.;* Liu, L. X.; Shi, R. L; Goebal, U. Structure and function of ETAA-16: A novel cell surface antigen in Ewing tumors. Cancer Immunology Immunotherapy 55 (2006) 363-374.
15. Liu, L. X.; Chen, G. F.; Ji, X.; Gao, G. X.* ZAP is a CRM1 dependent protein. Biochemical and Biophysical Research Communications 321 (2004) 517-523.
16. Jie Lan, Manshu Song, Chunhui Pan, Guoqing Zhuang, Youxin Wang, Wenzhan Ma, Qiaoyun Chu, Qingxuan Lai, Feng Xu, Yanli Li, Lixin Liu and Wei Wang. Association between dopaminergic genes (SLC6A3 and DRD2) and stuttering among Han Chinese, Journal of Human Genetics (Nature Publishing Group). 2009. 54: 457-460.
17. Wenzhan Ma, Jie Du, Qiaoyun Chu, Youxin Wang, Lixin Liu, Manshu Song, Wei Wang. hCLP46 regulates U937 cell proliferation via Notch signaling pathway. Biochemical and Biophysical Research Communication 2011:408:84-88.
18. Youxin Wang, Naibai Chang,Tian zhang, Hui Liu, Wenzhan Ma, Qiaoyun Chu, Qingxuan Lai, Lixin Liu, Wei Wang . Overexpression of human CAP10-like protein 46 KD in T-acute lymphoblastic leukemia and acute myelogenous leukemia. Genetic Testing and Molecular Biomarkers 2010:14:127-33.
19. Sheng A, Lan J, Wu H, Lu J, Wang Y, Chu Q, Jia Z, Song M, Liu L, Wang W. (2010) A clinical case control study on the association between mannose-binding lectin and susceptibility to HIV-1 infection among northern Han Chinese population. International Journal of Immunogentics. Int J Immunogenet. 2010 Dec;37(6):445-54. doi: 10.1111/j.1744-313X.2010.00946.x.
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