Mohanty, Smita - Oklahoma State University

个人简介

B.S. in Chemistry, Utkal University, Orissa, India, 1981 M.S. in Chemistry, Univeristy of Delhi, Delhi, India, 1983 Ph. D. in Organic Chemistry, University of Delhi, Delhi, India, 1988

研究领域

Structure-function studeis of both membrane and soluble protiens having critical biological function High-resolution NMR spectroscopy and protien crystallography for protien structure determination Computational chemistry for modelling, docking and small molecule library screening Protien-ligand interaction studies by biochemical and biophysical methods Molecular Biology including cloning and mutagenesis

近期论文

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Sevil Zencir, Monimoy Banerjee, Melanie J. Dobson, Ferhan Ayaydin, Elfrieda Ayaydin Fodor, Zeki Topcu,* and Smita Mohanty, New partner proteins containing novel internal recognition motif for human Glutaminase Interacting Protein (hGIP), Biochemical and Biophysical Research Communications, 2013, 432 (1), 10 – 15. * Dr. Zeki Topcu received Fulbright Fellowship and worked in my laboratory from 2009-2010. Uma V. Katre, Suman Mazumder, and Smita Mohanty, Structural insights into the ligand binding and releasing mechanism of Antheraea polyphemus PBP1: role of the C-terminal tail, Biochemistry, 2013, 52, 1037-1044. Chengdong Huang, Rajgopalan Bhaskaran and Smita Mohanty, Eukaryotic N-glycosylation Occurs Via Membrane-anchored C-terminal Domain of Stt3p Subunit of Oligosaccharyl Transferase, Journal of Biological Chemistry, 2012, 287 (39), 32450-32458. Monimoy Banerjee, David Zoetewey, Mohiudeen Ovee, Suman Mazumder, Valerie Petrenko, Tatiana Samoylove and Smita Mohanty, Specificity and promiscuity in human Glutaminase Interacting Protein (GIP) recognition: Insight from the binding of internal and C-terminal motif, Biochemistry, 2012, 51 (35), 6950–6960. Smita Mohanty, Moth Olfaction: A Model of Exquisite Sensitivity and Specificity, Biochem Physiol, 2012, 1:e106. doi:10.4172/bcpc.1000e106. Amit Kumar*, Priscilla Ward, Uma Katre and Smita Mohanty, A Novel Method of Production and Biophysical Characterization of a Mini-Membrane protein, Ost4p: A Subunit of Yeast Oligosaccharyl Transferase, Biopolymers, 2012,97, 499-507. *A. Kumar worked in the laboratory as a high school student. Currently an undergraduate student class of 2016 at NYU. Sevil Zencir, Mohiudeen Ovee, Melanie Donson, Monimoy Banerjee, Zeki Topcu* and Smita Mohanty, Identification of brain-specific angiogenesis inhibitor 2 as an ınteraction partner of glutaminase interacting protein, Biochem. Biophys. Res. Commun. 2011, 411, 792-797. *Dr. Zeki Topcu received Fulbright Fellowship and worked in my laboratory from 2009-2010. Janarthanan Krishnamoorthy and Smita Mohanty, Open-ITC: An alternate computational approach to analyze the ITC data of complex binding mechanisms, Journal of Molecular Recognition, 2011, 24 (6), 1056-1066. David Zoetewey, Mohiuddin Ovee, Monimoy Banerjee, Rajagopalan Bhaskaran and Smita Mohanty, Promiscuous Binding at the Crossroads of Numerous Cancer Pathways: Insight from the Binding of GIP with Glutaminase L, Biochemistry, 2011, 50, 3528-3539. Chengdong Huang and Smita Mohanty, Challenging the Limits: NMR Assignment of a 31 kDa Helical Membrane Protein, Journal of American Chemical Society, 2010, 132 (11),3662–3663. Chengdong Huang, Smita Mohanty and Monimoy Banerjee, A Novel Method of Production and Biophysical Characterization of the Catalytic Domain of Yeast Oligosaccharyl Transferase,Biochemistry, 2010, 49, 1115-1126. Uma V. Katre, Suman Mazumder, Rabi K. Prusti, and Smita Mohanty, Ligand Binding Turns Moth Pheromone-binding Protein into a pH Sensor: Effect On The Antheraea Polyphemus PBP1 Conformation, Journal of Biological Chemistry , 2009 , 284 (46), 32167-32177. Monimoy Banerjee, Chengdong Huang, Javier Marquez, and Smita Mohanty, Probing the structure, function and dynamics of human gulataminase-interacting protein (GIP): A possible target for drug design, Biochemistry, 2008, 47 (35), 9208-9219. Monimoy Banerjee, Erich Meyerowitz, Chengdong Huang & Smita Mohanty, Probing the Conformation and Dynamics of Allatostatin Neuropeptides: A Structural Model for Functional Differences, Peptides, 2008, 29(3):375-385. Priscilla Ward, Chengdong Huang, Monimoy Banerjee & Smita Mohanty, Interaction of Metal Ions with Glutaminase Interacting Protein (GIP): A Potential Role of GIP in Brain Diseases,Spectroscopy, 2008, Volume 22, No. 4, page 213-221 Joshua Ring, Rabi K. Prusti & Smita Mohanty, Chemical Communication: A visit with insects,Current Chemical Biology, 2008, 2, Number 1, 83-96. Sergey Zubkov, A. Gronenborn, I. L. Byeon & S. Mohanty, Structural consequences of the pH-induced conformational switch in A. polyphemus pheromone-binding protein: mechanisms of ligand release, Journal of Molecular Biology, 2005, 354, 1081-1090.