个人简介
彭军, 男,1968年8月出生,研究员、二级教授,博士生导师, 中南大学“升华学者计划”特聘教授。1991年毕业于湖南医科大学, 1997年获湖南医科大学生物化学硕士学位, 2002年获中南大学药理学博士学位。 2002-2007年在美国华盛顿州立大学从事博士后工作。现为中南大学湘雅药学院药理学系主任,兼任《中国动脉硬化杂志》编委、国际动脉硬化学会中国分会理事、中国动脉硬化专业委员会委员、中国药理学学会心血管专业委员会委员、中药与天然药物药理专业委员会委员、湖南省药学会理事、湖南省生理学会常务理事、湖南省药理学会秘书长等职。
研究领域
主要方向为内源性活性物质在心脑血管疾病中作用和机制及药物防治
近期论文
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Zhang YZ, Wang L, Zhang JJ, Xiong XM, Zhang D, Tang XM, Luo XJ, Ma QL, Peng J*(彭军,通讯作者). Vascular peroxide 1 promotes ox-LDL-induced programmed necrosis in endothelial cells through a mechanism involving β-catenin signaling. Atherosclerosis. 2018; 274:128-138. Zhang YS, Tang LJ, Tu H, Wang SJ, Liu B, Zhang XJ, Li NS, Luo XJ, Peng J*(彭军,通讯作者). Fasudil ameliorates the ischemia/reperfusion oxidative injury in rat hearts through suppression of myosin regulatory light chain/NADPH oxidase 2 pathway. Eur J Pharmacol. 2018;822:1-12. Zhang JJ, Zhang YZ, Peng JJ, Li NS, Xiong XM, Ma QL, Luo XJ, Liu B, Peng J*(彭军,通讯作者). Atorvastatin exerts inhibitory effect on endothelial senescence in hyperlipidemic rats through a mechanism involving down-regulation of miR-21-5p/203a-3p. Mech Ageing Dev. 2018; 169:10-18. Tian J, Guo S, Chen H, Peng JJ, Jia MM, Li NS, Zhang XJ, Yang J, Luo XJ, Peng J*(彭军,通讯作者). Combination of Emricasan with Ponatinib Synergistically Reduces Ischemia/Reperfusion Injury in Rat Brain Through Simultaneous Prevention of Apoptosis and Necroptosis. Transl Stroke Res. 2018; 9(4): 382-392. Peng JJ, Liu B, Xu JY, Peng J*(彭军,通讯作者), Luo XJ*. NADPH oxidase: its potential role in promotion of pulmonary arterial hypertension. Naunyn Schmiedebergs Arch Pharmacol. 2017; 390(4): 331-338 Li TB, Zhang JJ, Liu B, Luo XJ, Ma QL*, Peng J*(彭军,通讯作者). Dysfunction of endothelial progenitor cells in hyperlipidemic rats involves the increase of NADPH oxidase-derived reactive oxygen species production. Can J Physiol Pharmacol. 2017; 95(5):474-480. Liu B, Ren KD, Peng JJ, Li T, Luo XJ, Fan C, Yang JF, Peng J*(彭军,通讯作者). Suppression of NADPH oxidase attenuates hypoxia-induced dysfunctions of endothelial progenitor cells. Biochem Biophys Res Commun. 2017; 482(4):1080-1087. Li JH, Ju GX, Jiang JL, Li NS, Peng J*(彭军,通讯作者), Luo XJ*. Lipoic acid protects gastric mucosa from ethanol-induced injury in rat through a mechanism involving aldehyde dehydrogenase 2 activation. Alcohol. 2016; 56:21-28. doi: 10.1016/j.alcohol.2016.10.004. 9.Yang ZB, Li TB, Zhang Z, Ren KD, Zheng ZF, Peng J, Luo XJ. The Diagnostic Value of Circulating Brain-specific MicroRNAs for Ischemic Stroke. Intern Med. 2016;55(10):1279-86. Peng J*(彭军,并列第一), Ren KD*, Yang J, Luo XJ. Mitochondrial E3 ubiquitin ligase 1: A key enzyme in regulation of mitochondrial dynamics and functions. Mitochondrion. 2016; 28:49-53. Li TB, Zhang JJ, Liu B, Liu WQ, Wu Y, Xiong XM, Luo XJ, Ma QL, Peng J*(彭军,通讯作者). Involvement of NADPH oxidases and non-muscle myosin light chain in senescence of endothelial progenitor cells in hyperlipidemia. Naunyn Schmiedebergs Arch Pharmacol. 2016; 389(3):289-302. Wu Y, Zhang JJ, Li TB, Liu WQ, Li LS, Luo XJ, Jiang JL, Ma QL, Yang ZC, Peng J*(彭军,通讯作者). Phosphorylation of Nonmuscle Myosin Light Chain Promotes Endothelial Injury in Hyperlipidemic Rats Through a Mechanism Involving Downregulation of Dimethylarginine Dimethylaminohydrolase 2. J Cardiovasc Pharmacol Ther. 2016; 21(6):536-548. Liu B, Li T, Peng JJ, Zhang JJ, Liu WQ, Luo XJ, Ma QL, Gong ZC, Peng J*(彭军,通讯作者). Non-muscle myosin light chain promotes endothelial progenitor cells senescence and dysfunction in pulmonary hypertensive rats through up-regulation of NADPH oxidase. Eur J Pharmacol. 2016;775:67-77. Yang ZB, Luo XJ, Ren KD, Peng JJ, Tan B, Liu B, Lou Z, Xiong XM, Zhang XJ, Ren X, Peng J*(彭军,通讯作者). Beneficial effect of magnesium lithospermate B on cerebral ischemia-reperfusion injury in rats involves the regulation of miR-107/glutamate transporter 1 pathway. Eur J Pharmacol. 2015; 766: 91-98. Zhang HF, Li TB, Liu B, Lou Z, Zhang JJ, Peng JJ, Zhang XJ, Ma QL, Peng J*, Luo XJ. Inhibition of myosin light chain kinase reduces NADPH oxidase-mediated oxidative injury in rat brain following cerebral ischemia/reperfusion. Naunyn Schmiedebergs Arch Pharmacol. 2015; 388(9): 953-632.