朱曲波 - 中南大学 - 湘雅药学院

个人简介

同年赴美，于Texas A&M University Dr. Robert Tsai课题组从事干细胞及癌症方面的研究。2009年5月获得BiomedicalSciences的博士学位。2009年9月至2011年8月在美国CaseWestern Reserve University药理学系Dr. Krzysztof Palczewski实验室从事博士后研究工作

研究领域

主要从事microRNA在癌症中以及眼科疾病中的研究工作以及药物胃肠道转运的研究

近期论文

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Li P, Sheng C, Huang L, Zhang H, Huang L, Cheng Z,Zhu Q*.MiR-183/-96/-182 cluster isup-regulated in most breast cancers and increases cell proliferation andmigration. Breast Cancer Research. 2014 JWF MS ID: 13058_2014_473 Zhu Q, Liu Z, Li P, Cheng Z*. Druginteraction studies reveal that simotinib upregulates intestinal absorption byincreasing the paracellular permeability of intestinal epithelial cells. DrugMetab Pharmacokinet. 2014;29(4):317-24. Meng L, Hsu JK,Zhu Q, Lin T, Tsai RY*. Nucleostemin inhibitsTRF1 dimerization and shortens its dynamic association with the telomere. JCell Sci. 2011 Nov 1;124(Pt 21):3706-14. Zhu Q, Sun W, Okano K, Chen Y, Zhang N,Maeda T, Palczewski K*. Sponge transgenic mouse model reveals important rolesfor the microRNA-183 (miR-183)/96/182 cluster in postmitotic photoreceptors ofthe retina. J Biol Chem. 2011 Sep 9;286(36):31749-60. Zhu Q, Meng L, Hsu JK, Lin T, TeishimaJ, Tsai RY*. GNL3L stabilizes the TRF1 complex and promotes mitotic transition.J Cell Biol. 2009 Jun 1;185(5):827-39. Meng L,Zhu Q, Tsai RY*. Nucleolar trafficking ofnucleostemin family proteins: common versus protein-specific mechanisms. MolCell Biol. 2007 Dec;27(24):8670-82.·Yasumoto H, Meng L, Lin T, Zhu Q, Tsai RY*.GNL3L inhibitsactivity of estrogen-related receptor gamma by competing for coactivatorbinding.J Cell Sci. 2007 Aug 1;120(Pt 15):2532-43. Zhu Q, Yasumoto H, Tsai RY*.Nucleostemin delays cellular senescence and negatively regulates TRF1 proteinstability. Mol Cell Biol. 2006 Dec;26(24):9279-90.