个人简介
教育经历
1979-1983北京医学院药学系(现北京大学药学院)药物化学专业毕业,获学士学位
2009-2010 Rutgers, The State University of New Jersey药学院访问学者
研究领域
合成药物化学:抗纤维化药物和抗糖尿病肾病药物的设计与合成;基于新机制的抗肿瘤药物的设计与合成;基于新靶点的抗炎药物的设计与合成。
近期论文
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1.Ling Wu , Bin Liu , Qianbin Li , Jun Chen , Lijian Tao and Gaoyun Hu* , Design, Synthesis and Anti-fibrosis Activity Study of N1-Substituted Phenylhydroquinolinone Derivatives Molecules 2012, 17, 1373-1387
2.Jun Chen, Miao-Miao Lu, Bin Liu, Zhuo Chen, Qian-Bin Li, Li-Jian Tao, Gao-Yun Hu*, Synthesis and strrelationship of 5-substituent-2(1H)-pyridone derivatives as anti-fibrosis agents Bioorganic & Medicinal Chemistry Letters 2012, 22, 2300–2302
3.Chun Wu, Yanpeng Hu, Qianbin Li, Limei He, Jun Chen, Zeneng Cheng, Yuanjian Li,and Gaoyun Hu*, Synthesis, Pharmacokinetics, and Pharmacodynamics Studies of Valsartan Peptide Derivatives Arch. Pharm. Chem. Life Sci. 2012, 345, 393–400
4.Zhuo Chen , Gaoyun Hu,*, Dai Li , Jun Chen , Yuanjian Li , Huayong Zhou , Ye Xie, Synthesis and vasodilator effects of rutaecarpine analogues which might be involved transient receptor potential vanilloid subfamily, member 1 (TRPV1) Bioorganic & Medicinal Chemistry 2009, 17 , 2351–2359
5.Hua Yang, Gao-Yun Hu,* Jun Chen, Yi Wang and Zhong-Hua Wang, Synthesis, resolution, and antiplatelet activity of 3-substituted 1(3H)-isobenzofuranone Bioorganic & Medicinal Chemistry Letters 2007, 17 , 5210–5213