个人简介
中南大学药学院副院长,中南大学分子影像研究中心探针室主任。荣获教育部新世纪优秀人才,湖南省自然科学杰出青年,湖南省高校药物化学学科带头人等荣誉。现担任国际SCI期刊Anti-Cancer Agents in Med Chem、British J Pharma Res和International J Drug Discovery等学术期刊副主编。2004年毕业于德国明斯特大学,获得理学博士学位;2005-2006年作为访问学者留学美国密苏里-哥伦比亚大学;2006-2009年担任美国田纳西大学高级科研助理;2009年3月起在中南大学药学院工作。
教育和工作经历
1994.9-1998.6:吉林大学化学系,学士
1998.9-2001.6:中国科学院上海有机化学研究所,硕士
2001.11-2004.11:德国明斯特大学,博士
2005.3-2006.3:美国密苏里-哥伦比亚大学,访问学者
2006.3-2009.2:美国田纳西大学医学院
2009.3-现在:中南大学药学院,升华学者特聘教授,博士生导师
研究领域
研究方向为分子影像药物和分子探针的设计、合成和评价;天然活性化合物的合成及先导药物的发现等。
近期论文
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1.Wenbin Zeng*, Xiaobo Wang, Pengfei Xu, Gang Liu, Henry S. Eden and Xiaoyuan Chen*. Molecular imaging of apoptosis: from micro to macro. Theranostics,2015, 5(6), 559-582. DOI: 10.7150/thno.11548. (SCI, IF=7.827)
2.Pengfei Xu, Tang Gao, Meihui Liu, Hailiang Zhang and Wenbin Zeng*. A novel excited-state intramolecular proton transfer (ESIPT) dye with unique near-IR keto emission and its application in detection of hydrogen sulfide. Analyst,2015, 140, 1814-1816. DOI: 10.1039/C4AN02285H. (SCI, IF=3.906)
3.Kunzhu Huang,Lun Yu,Pengfei Xu,Xintong ZhangandWenbin Zeng*. A novel FRET-based ratiometric fluorescent probe for highly sensitive detection of hydrogen sulfide. RSC Adv,2015, 5, 17797-17801. DOI: 10.1039/C4RA16578K. (SCI, IF=3.708)
4.Min Tang, Jiaguo Huang, Xinxian Weng, Lifang Yang, Meihui Liu, Ming Zhou, Xiaobo Wang, Jinghe Gao, Wei Yi, Wenbin Zeng*, Lunquan Sun* and Ya Cao*. Evaluation of a dansyl-based amino acid DNSBA as an imaging probe for apoptosis detection. Apoptosis,2015, 20, 410-420. (SCI, IF=3.614)
5.Kunzhu Huang, Meihui Liu, Zhiguo Liu, Dongsheng Cao, Jing Hou and Wenbin Zeng*. Ratiometric and colorimetric detection of hydrogen sulfide with high selectivity and sensitivity using a novel FRET-based fluorescence probe. Dyes Pigm,2015, 118, 88-95. DOI:10.1016/j.dyepig.2015.03.007. (SCI, IF=3.468)
6.Tang Gao, Pengfei Xu, Meihui Li, Anyao Bi, Pengzhi Hu, Wei Wang and Wenbin Zeng*. A novel water-soluble ESIPT fluorescent probe with high quantum yield and red emission for ratiometric detectionto inorganic andorganic palladium.Chem – An AsianJ,2015, 10, DOI: 10.1002/asia.201500114. (SCI, IF=3.935)
7.Pengfei Xu, Kunzhu Huang, Dongsheng Cao and Wenbin Zeng*. A green and efficient one-pot synthesis of 1, 2, 3-trisubstituted pyrroles via iodine-catalyzed tandem reaction. Lett in Org Chem,2015, 12(4), 290-298. (SCI)