个人简介
A.B. Genetics, U.C. Berkeley, 1986
Ph.D. Molecular Biology, University of Pennsylvania, 1996
近期论文
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Michael, W. M. (2016). Cyclin CYB-3 controls both S-phase and mitosis and is asymmetrically distributed in the early C. elegans embryo. Development. Vol. 143 (17), pp. 3119-3127. PubMed Web Address
Acevedo, J., Yan, S., Michael, W. M. (2016). Direct Binding to Replication Protein A (RPA)-coated Single-stranded DNA Allows Recruitment of the ATR Activator TopBP1 to Sites of DNA Damage. The Journal of Biological Chemistry. Vol. 291 (25), pp. 13124-31. PubMed Web Address
Butuci, M., Williams, A. B., Wong, M. M., Kramer, B., Michael, W. M. (2015). Zygotic Genome Activation Triggers Chromosome Damage and Checkpoint Signaling in C. elegans Primordial Germ Cells. Developmental Cell. Vol. 34 (1), pp. 85-95. PubMed Web Address
Butuci, M., Wong, M. M., Michael, W. M. (2015). Trouble in Transitioning: activation of zygotic transcription can lead to DNA breakage and genome instability. Worm. Vol. 4 (4), pp. e1115946. PubMed Web Address
Bai, L., Michael, W. M., Yan, S. (2014). Importin ?-dependent nuclear import of TopBP1 in ATR-Chk1 checkpoint in Xenopus egg extracts. Cellular Signalling. Vol. 26 (5), pp. 857-67. PubMed Web Address
Murphy, C. M., Michael, W. M. (2013). Control of DNA replication by the nucleus/cytoplasm ratio in Xenopus. The Journal of Biological Chemistry. Vol. 288 (41), pp. 29382-93. PubMed Web Address
Van, C., Yan, S., Michael, W. M., Waga, S., Cimprich, K. (2010). Continued primer synthesis at stalled replication forks contributes to checkpoint activation. The Journal of Cell Biology. Vol. 189 (2), pp. 233-46. PubMed Web Address
Williams, A. B., Michael, W. M. (2010). Eviction notice: new insights into Rad51 removal from DNA during homologous recombination. Molecular Cell. Vol. 37 (2), pp. 157-8. PubMed Web Address
Yan, S., Michael, W. M. (2009). TopBP1 and DNA polymerase alpha-mediated recruitment of the 9-1-1 complex to stalled replication forks: implications for a replication restart-based mechanism for ATR checkpoint activation. Cell Cycle. Vol. 8 (18), pp. 2877-84. PubMed Web Address
Yan, S., Michael, W. M. (2009). TopBP1 and DNA polymerase-alpha directly recruit the 9-1-1 complex to stalled DNA replication forks. The Journal of Cell Biology. Vol. 184 (6), pp. 793-804. PubMed Web Address
Kim, S. H., Michael, W. M. (2008). Regulated proteolysis of DNA polymerase eta during the DNA-damage response in C. elegans. Molecular Cell. Vol. 32 (6), pp. 757-66. PubMed Web Address